amsacrine has been researched along with Chromosome Inversion in 2 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Chromosome Inversion: An aberration in which a chromosomal segment is deleted and reinserted in the same place but turned 180 degrees from its original orientation, so that the gene sequence for the segment is reversed with respect to that of the rest of the chromosome.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghaddar, HM | 1 |
| Plunkett, W | 2 |
| Kantarjian, HM | 1 |
| Pierce, S | 1 |
| Freireich, EJ | 2 |
| Keating, MJ | 2 |
| Estey, EH | 2 |
| McCredie, KB | 1 |
1 trial available for amsacrine and Chromosome Inversion
| Article | Year |
|---|---|
Long-term results following treatment of newly-diagnosed acute myelogenous leukemia with continuous-infusion high-dose cytosine arabinoside.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocol | 1994 |
1 other study available for amsacrine and Chromosome Inversion
| Article | Year |
|---|---|
Cellular ara-CTP pharmacokinetics, response, and karyotype in newly diagnosed acute myelogenous leukemia.
Topics: Amsacrine; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Chromosome Deletion; Chromosom | 1990 |