amsacrine has been researched along with Chromosome-Defective Micronuclei in 4 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stopper, H | 2 |
| Eckert, I | 1 |
| Wagener, P | 1 |
| Schulz, WA | 1 |
| Boos, G | 1 |
| Ferguson, LR | 2 |
| Hill, CL | 1 |
| Morecombe, P | 1 |
| Hill, CM | 1 |
| Baguley, BC | 1 |
4 other studies available for amsacrine and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Formation of micronuclei and inhibition of topoisomerase II in the comet assay in mammalian cells with altered DNA methylation.
Topics: Amsacrine; Animals; Azacitidine; Carcinoma, Embryonal; Cell Differentiation; DNA Methylation; DNA, N | 1997 |
Genotoxicity of several clinically used topoisomerase II inhibitors.
Topics: Amsacrine; Animals; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Enzyme Inhibitors; Et | 2000 |
Induction of resistance to 6-thioguanine and cytarabine by a range of anticancer drugs in Chinese hamster AA8 cells.
Topics: Amsacrine; Animals; Antineoplastic Agents; Bleomycin; Carmustine; CHO Cells; Clone Cells; Cricetinae | 1992 |
Genetic toxicology of tricyclic carboxamides, a new class of DNA binding antitumour agent.
Topics: Acridines; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cells, Cultured; Cricetinae; C | 1990 |