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amsacrine and Cell Transformation, Neoplastic

amsacrine has been researched along with Cell Transformation, Neoplastic in 4 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cunningham, JM1
Francis, GE1
Holland, MJ1
Pirollo, KF1
Chang, EH1
Ferguson, LR2
van Zijl, P2
Baguley, BC1
Nesnow, S1
Jensen, CG1
Wilson, WR1
Bleumink, AR1

Other Studies

4 other studies available for amsacrine and Cell Transformation, Neoplastic

ArticleYear
Aberrant DNA topoisomerase II activity, radioresistance and inherited susceptibility to cancer.
    British journal of cancer, 1991, Volume: 63, Issue:1

    Topics: Amsacrine; Ataxia Telangiectasia; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cytarabi

1991
Comparison of the mutagenicity of amsacrine with that of a new clinical analogue, CI-921.
    Mutation research, 1988, Volume: 204, Issue:2

    Topics: Amsacrine; Animals; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Chromosome Aberrations

1988
Morphological transformation and chromosome damage by amsacrine in C3H/10T1/2 clone 8 cells.
    Mutation research, 1986, Volume: 170, Issue:3

    Topics: Aminoacridines; Amsacrine; Animals; Cell Line; Cell Nucleus; Cell Survival; Cell Transformation, Neo

1986
Effects of amsacrine and other DNA-intercalating drugs on nuclear and nucleolar structure in cultured V79 Chinese hamster cells and PtK2 rat kangaroo cells.
    Cancer research, 1985, Volume: 45, Issue:2

    Topics: Aminacrine; Aminoacridines; Amsacrine; Animals; Anthraquinones; Cell Nucleolus; Cell Nucleus; Cell S

1985