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amsacrine and Carcinoma, Lewis Lung

amsacrine has been researched along with Carcinoma, Lewis Lung in 4 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baguley, BC4
Leteurtre, F1
Riou, JF1
Finlay, GJ4
Pommier, Y1
Moreland, N1
Dragunow, M1
Holdaway, KM1
Turnbull, RM1
Meczes, EL1
Perenna Rogers, M1
Lock, RB1
Sullivan, DM1
Austin, CA1

Other Studies

4 other studies available for amsacrine and Carcinoma, Lewis Lung

ArticleYear
A carbamate analogue of amsacrine with activity against non-cycling cells stimulates topoisomerase II cleavage at DNA sites distinct from those of amsacrine.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:2

    Topics: Amsacrine; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; DNA Fragmentation; DNA Topoisomera

1997
Cellular responses to methyl-N-[4-9-acridinylamino)-2-methoxyphenyl] carbamate hydrochloride, an analogue of amsacrine active against non-proliferating cells.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:10

    Topics: Amsacrine; Animals; Antineoplastic Agents; Aphidicolin; Carcinoma, Lewis Lung; Cell Cycle; Cell Surv

1997
Carbamate analogues of amsacrine active against non-cycling cells: relative activity against topoisomerases IIalpha and beta.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:4

    Topics: Acridines; Amsacrine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Lewis Lung; Cel

1999
Effects of protein binding on the in vitro activity of antitumour acridine derivatives and related anticancer drugs.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:5

    Topics: Amsacrine; Animals; Antineoplastic Agents; Blood Proteins; Carcinoma, Lewis Lung; Cattle; Doxorubici

2000