amsacrine has been researched along with Carcinoma, Lewis Lung in 4 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baguley, BC | 4 |
| Leteurtre, F | 1 |
| Riou, JF | 1 |
| Finlay, GJ | 4 |
| Pommier, Y | 1 |
| Moreland, N | 1 |
| Dragunow, M | 1 |
| Holdaway, KM | 1 |
| Turnbull, RM | 1 |
| Meczes, EL | 1 |
| Perenna Rogers, M | 1 |
| Lock, RB | 1 |
| Sullivan, DM | 1 |
| Austin, CA | 1 |
4 other studies available for amsacrine and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
A carbamate analogue of amsacrine with activity against non-cycling cells stimulates topoisomerase II cleavage at DNA sites distinct from those of amsacrine.
Topics: Amsacrine; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; DNA Fragmentation; DNA Topoisomera | 1997 |
Cellular responses to methyl-N-[4-9-acridinylamino)-2-methoxyphenyl] carbamate hydrochloride, an analogue of amsacrine active against non-proliferating cells.
Topics: Amsacrine; Animals; Antineoplastic Agents; Aphidicolin; Carcinoma, Lewis Lung; Cell Cycle; Cell Surv | 1997 |
Carbamate analogues of amsacrine active against non-cycling cells: relative activity against topoisomerases IIalpha and beta.
Topics: Acridines; Amsacrine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Lewis Lung; Cel | 1999 |
Effects of protein binding on the in vitro activity of antitumour acridine derivatives and related anticancer drugs.
Topics: Amsacrine; Animals; Antineoplastic Agents; Blood Proteins; Carcinoma, Lewis Lung; Cattle; Doxorubici | 2000 |