amsacrine has been researched along with Body Weight in 4 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Excerpt | Relevance | Reference |
---|---|---|
" The toxic effect was also lower for liposome preparations." | 1.28 | [Examination of the toxicity of the liposomal form of amsacrine and retinoic acid]. ( Tarasiuk, A, 1992) |
"Amsacrine was administered intraperitoneally to groups of 12 male rats in single weekly doses of 12, 6, and 3 mg/m2 for 13 weeks." | 1.27 | Cardiotoxicity study of amsacrine in rats. ( Anderson, JA; de la Iglesia, FA; Fitzgerald, JE; Jayasekara, U; Kim, SN; Watkins, JR, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 3 (75.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Tarasiuk, A | 1 |
Bailly, C | 1 |
Collyn-d'Hooghe, M | 1 |
Lantoine, D | 1 |
Fournier, C | 1 |
Hecquet, B | 1 |
Fosse, P | 1 |
Saucier, JM | 1 |
Colson, P | 1 |
Houssier, C | 1 |
Hénichart, JP | 1 |
Boven, E | 1 |
Winograd, B | 1 |
Berger, DP | 1 |
Dumont, MP | 1 |
Braakhuis, BJ | 1 |
Fodstad, O | 1 |
Langdon, S | 1 |
Fiebig, HH | 1 |
Kim, SN | 1 |
Watkins, JR | 1 |
Jayasekara, U | 1 |
Anderson, JA | 1 |
Fitzgerald, JE | 1 |
de la Iglesia, FA | 1 |
1 trial available for amsacrine and Body Weight
Article | Year |
---|---|
Phase II preclinical drug screening in human tumor xenografts: a first European multicenter collaborative study.
Topics: Amsacrine; Animals; Antineoplastic Agents; Biphenyl Compounds; Body Weight; Doxorubicin; Drug Screen | 1992 |
3 other studies available for amsacrine and Body Weight
Article | Year |
---|---|
[Examination of the toxicity of the liposomal form of amsacrine and retinoic acid].
Topics: Amsacrine; Animals; Body Weight; Drug Carriers; Liposomes; Male; Mice; Survival Rate; Tretinoin | 1992 |
Biological activity and molecular interaction of a netropsin-acridine hybrid ligand with chromatin and topoisomerase II.
Topics: Amsacrine; Animals; Body Weight; Cell Division; Chromatin; DNA Damage; Drug Design; Female; Fluorour | 1992 |
Cardiotoxicity study of amsacrine in rats.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Body Weight; Creatine Kinase; Heart; Male | 1985 |