amsacrine has been researched along with Autosomal Chromosome Disorders in 2 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We propose two mechanisms for aneuploidy by amsacrine (or related topo II poisons), either of which can be readily detected using FISH." | 1.29 | Application of fluorescence in situ hybridisation to study the relationship between cytotoxicity, chromosome aberrations, and changes in chromosome number after treatment with the topoisomerase II inhibitor amsacrine. ( Baguley, BC; Ferguson, LR; Holdaway, KM; Whiteside, G, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilson, WR | 1 |
| Harris, NM | 1 |
| Ferguson, LR | 2 |
| Whiteside, G | 1 |
| Holdaway, KM | 1 |
| Baguley, BC | 1 |
2 other studies available for amsacrine and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Comparison of the mutagenic and clastogenic activity of amsacrine and other DNA-intercalating drugs in cultured V79 Chinese hamster cells.
Topics: Aminoacridines; Amsacrine; Animals; Carcinogens; Cell Division; Cell Line; Cell Survival; Chromosome | 1984 |
Application of fluorescence in situ hybridisation to study the relationship between cytotoxicity, chromosome aberrations, and changes in chromosome number after treatment with the topoisomerase II inhibitor amsacrine.
Topics: Amsacrine; Analysis of Variance; Aneuploidy; Animals; Antineoplastic Agents; Cell Cycle; Cell Divisi | 1996 |