Page last updated: 2024-10-22

amsacrine and Ataxia Telangiectasia Syndrome

amsacrine has been researched along with Ataxia Telangiectasia Syndrome in 5 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaufmann, WK1
Boyer, JC1
Estabrooks, LL1
Wilson, SJ1
Cunningham, JM1
Francis, GE1
Holland, MJ1
Pirollo, KF1
Chang, EH1
Henner, WD1
Blazka, ME1
Smith, PJ1
Makinson, TA1
Davies, SM1
Harris, AL1
Hickson, ID1

Other Studies

5 other studies available for amsacrine and Ataxia Telangiectasia Syndrome

ArticleYear
Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes.
    Molecular and cellular biology, 1991, Volume: 11, Issue:7

    Topics: Amsacrine; Ataxia Telangiectasia; Camptothecin; Cell Line; DNA; DNA Damage; DNA Replication; Drug Re

1991
Aberrant DNA topoisomerase II activity, radioresistance and inherited susceptibility to cancer.
    British journal of cancer, 1991, Volume: 63, Issue:1

    Topics: Amsacrine; Ataxia Telangiectasia; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cytarabi

1991
Hypersensitivity of cultured ataxia-telangiectasia cells to etoposide.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:6

    Topics: Aminoacridines; Amsacrine; Ataxia Telangiectasia; Bleomycin; Cell Survival; Cells, Cultured; DNA; Et

1986
Cellular consequences of overproduction of DNA topoisomerase II in an ataxia-telangiectasia cell line.
    Cancer research, 1989, Mar-01, Volume: 49, Issue:5

    Topics: Amsacrine; Ataxia Telangiectasia; Cell Line; DNA; DNA Damage; DNA Topoisomerases, Type II; Humans

1989
Overproduction of topoisomerase II in an ataxia telangiectasia fibroblast cell line: comparison with a topoisomerase II-overproducing hamster cell mutant.
    Nucleic acids research, 1989, Feb-25, Volume: 17, Issue:4

    Topics: Amsacrine; Animals; Ataxia Telangiectasia; Blotting, Western; Camptothecin; Cell Line; Cell Survival

1989