amsacrine has been researched along with Arrhythmias, Cardiac in 7 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amsacrine is an antileukemia drug being widely used in North America, Europe, Australia, and New Zealand." | 5.06 | Amsacrine-associated cardiotoxicity: an analysis of 82 cases. ( Grillo-López, AJ; Hess, F; Marsoni, S; Posada, JG; Ross, BJ; Weiss, RB, 1986) |
| "The ECG effect of amsacrine (m-AMSA) was evaluated in 12 consecutive patients with leukemia." | 3.67 | Acute electrocardiographic changes induced by amsacrine. ( Hasin, Y; Shinar, E, 1984) |
| "There is emerging clinical evidence that amsacrine (m-AMSA) administration may be associated with cardiotoxic effects such as severe, even fatal, ventricular arrhythmias and impairment of the inotropic performance of the heart." | 3.66 | Effects of amsacrine (m-AMSA), a new aminoacridine antitumor drug, on the rabbit heart. ( Crescimanno, M; D'Alessandro, N; Flandina, C; Gebbia, N; Leto, G; Messina, L; Tumminello, FM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, BY | 1 |
| Coult, J | 1 |
| Blackwood, J | 1 |
| Kwok, H | 1 |
| Rajah, A | 1 |
| Goldenberg, I | 1 |
| Sotoodehenia, N | 1 |
| Harris, JR | 1 |
| Kudenchuk, PJ | 1 |
| Rea, TD | 1 |
| Weiss, RB | 2 |
| Moquin, D | 1 |
| Adams, JD | 1 |
| Griffin, JD | 1 |
| Zimbler, H | 1 |
| Shinar, E | 1 |
| Hasin, Y | 1 |
| D'Alessandro, N | 1 |
| Gebbia, N | 1 |
| Crescimanno, M | 1 |
| Flandina, C | 1 |
| Leto, G | 1 |
| Tumminello, FM | 1 |
| Messina, L | 1 |
| Grillo-López, AJ | 1 |
| Marsoni, S | 1 |
| Posada, JG | 1 |
| Hess, F | 1 |
| Ross, BJ | 1 |
| Feldman, EJ | 1 |
| Arlin, ZA | 1 |
| Sullivan, P | 1 |
| Engelking, C | 1 |
| Civin, CI | 1 |
| Krischer, JP | 1 |
| Land, VJ | 1 |
| Nitschke, R | 1 |
| Kamen, B | 1 |
| Vats, T | 1 |
1 trial available for amsacrine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Amsacrine-associated cardiotoxicity: an analysis of 82 cases.
Topics: Adolescent; Aminoacridines; Amsacrine; Antineoplastic Agents; Arrhythmias, Cardiac; Cardiomyopathies | 1986 |
6 other studies available for amsacrine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Age, sex, and survival following ventricular fibrillation cardiac arrest: A mechanistic evaluation of the ECG waveform.
Topics: Aged; Amsacrine; Arrhythmias, Cardiac; Biological Products; Cardiopulmonary Resuscitation; Cohort St | 2023 |
Electrocardiogram abnormalities induced by amsacrine.
Topics: Aminoacridines; Amsacrine; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Leukemia, Lymp | 1983 |
Acute electrocardiographic changes induced by amsacrine.
Topics: Acute Disease; Adolescent; Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic C | 1984 |
Effects of amsacrine (m-AMSA), a new aminoacridine antitumor drug, on the rabbit heart.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Arrhythmias, Cardiac; Depression, Chemica | 1983 |
Preventing amsacrine-induced cardiac arrhythmias.
Topics: Amsacrine; Arrhythmias, Cardiac; Humans; Potassium Chloride | 1987 |
Pediatric oncology group phase II trial of amsacrine in children with solid tumors.
Topics: Age Factors; Aminoacridines; Amsacrine; Arrhythmias, Cardiac; Child; Child, Preschool; Drug Evaluati | 1985 |