amsacrine has been researched along with Arrhythmia in 7 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amsacrine is an antileukemia drug being widely used in North America, Europe, Australia, and New Zealand." | 5.06 | Amsacrine-associated cardiotoxicity: an analysis of 82 cases. ( Grillo-López, AJ; Hess, F; Marsoni, S; Posada, JG; Ross, BJ; Weiss, RB, 1986) |
| "The ECG effect of amsacrine (m-AMSA) was evaluated in 12 consecutive patients with leukemia." | 3.67 | Acute electrocardiographic changes induced by amsacrine. ( Hasin, Y; Shinar, E, 1984) |
| "There is emerging clinical evidence that amsacrine (m-AMSA) administration may be associated with cardiotoxic effects such as severe, even fatal, ventricular arrhythmias and impairment of the inotropic performance of the heart." | 3.66 | Effects of amsacrine (m-AMSA), a new aminoacridine antitumor drug, on the rabbit heart. ( Crescimanno, M; D'Alessandro, N; Flandina, C; Gebbia, N; Leto, G; Messina, L; Tumminello, FM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, BY | 1 |
| Coult, J | 1 |
| Blackwood, J | 1 |
| Kwok, H | 1 |
| Rajah, A | 1 |
| Goldenberg, I | 1 |
| Sotoodehenia, N | 1 |
| Harris, JR | 1 |
| Kudenchuk, PJ | 1 |
| Rea, TD | 1 |
| Weiss, RB | 2 |
| Moquin, D | 1 |
| Adams, JD | 1 |
| Griffin, JD | 1 |
| Zimbler, H | 1 |
| Shinar, E | 1 |
| Hasin, Y | 1 |
| D'Alessandro, N | 1 |
| Gebbia, N | 1 |
| Crescimanno, M | 1 |
| Flandina, C | 1 |
| Leto, G | 1 |
| Tumminello, FM | 1 |
| Messina, L | 1 |
| Grillo-López, AJ | 1 |
| Marsoni, S | 1 |
| Posada, JG | 1 |
| Hess, F | 1 |
| Ross, BJ | 1 |
| Feldman, EJ | 1 |
| Arlin, ZA | 1 |
| Sullivan, P | 1 |
| Engelking, C | 1 |
| Civin, CI | 1 |
| Krischer, JP | 1 |
| Land, VJ | 1 |
| Nitschke, R | 1 |
| Kamen, B | 1 |
| Vats, T | 1 |
1 trial available for amsacrine and Arrhythmia
| Article | Year |
|---|---|
Amsacrine-associated cardiotoxicity: an analysis of 82 cases.
Topics: Adolescent; Aminoacridines; Amsacrine; Antineoplastic Agents; Arrhythmias, Cardiac; Cardiomyopathies | 1986 |
6 other studies available for amsacrine and Arrhythmia
| Article | Year |
|---|---|
Age, sex, and survival following ventricular fibrillation cardiac arrest: A mechanistic evaluation of the ECG waveform.
Topics: Aged; Amsacrine; Arrhythmias, Cardiac; Biological Products; Cardiopulmonary Resuscitation; Cohort St | 2023 |
Electrocardiogram abnormalities induced by amsacrine.
Topics: Aminoacridines; Amsacrine; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Leukemia, Lymp | 1983 |
Acute electrocardiographic changes induced by amsacrine.
Topics: Acute Disease; Adolescent; Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic C | 1984 |
Effects of amsacrine (m-AMSA), a new aminoacridine antitumor drug, on the rabbit heart.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Arrhythmias, Cardiac; Depression, Chemica | 1983 |
Preventing amsacrine-induced cardiac arrhythmias.
Topics: Amsacrine; Arrhythmias, Cardiac; Humans; Potassium Chloride | 1987 |
Pediatric oncology group phase II trial of amsacrine in children with solid tumors.
Topics: Age Factors; Aminoacridines; Amsacrine; Arrhythmias, Cardiac; Child; Child, Preschool; Drug Evaluati | 1985 |