amsacrine has been researched along with Aneuploid in 5 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possible risk of aneuploidy induction by the cancer chemotherapeutic drugs amsacrine (AMSA) and nocodazole (NOC) was investigated in male mice." | 1.35 | The chemotherapeutic agents nocodazole and amsacrine cause meiotic delay and non-disjunction in spermatocytes of mice. ( Adler, ID; Attia, SM; Badary, OA; Hamada, FM; Hrabé de Angelis, M, 2008) |
| "We propose two mechanisms for aneuploidy by amsacrine (or related topo II poisons), either of which can be readily detected using FISH." | 1.29 | Application of fluorescence in situ hybridisation to study the relationship between cytotoxicity, chromosome aberrations, and changes in chromosome number after treatment with the topoisomerase II inhibitor amsacrine. ( Baguley, BC; Ferguson, LR; Holdaway, KM; Whiteside, G, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parry, JM | 1 |
| Fowler, P | 1 |
| Quick, E | 1 |
| Parry, EM | 1 |
| Attia, SM | 1 |
| Badary, OA | 1 |
| Hamada, FM | 1 |
| Hrabé de Angelis, M | 1 |
| Adler, ID | 1 |
| Thomas, X | 1 |
| Archimbaud, E | 1 |
| Charrin, C | 1 |
| Magaud, JP | 1 |
| Fiere, D | 1 |
| Ferguson, LR | 1 |
| Whiteside, G | 1 |
| Holdaway, KM | 1 |
| Baguley, BC | 1 |
| Freireich, EJ | 1 |
1 review available for amsacrine and Aneuploid
| Article | Year |
|---|---|
New strategies in the management of acute leukemias.
Topics: Acute Disease; Amsacrine; Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pr | 1987 |
4 other studies available for amsacrine and Aneuploid
| Article | Year |
|---|---|
Investigations into the biological relevance of in vitro clastogenic and aneugenic activity.
Topics: Alkylating Agents; Amsacrine; Aneuploidy; Cells, Cultured; Chromosome Aberrations; Chromosomes, Huma | 2004 |
The chemotherapeutic agents nocodazole and amsacrine cause meiotic delay and non-disjunction in spermatocytes of mice.
Topics: Amsacrine; Aneuploidy; Animals; Antineoplastic Agents; In Situ Hybridization, Fluorescence; Injectio | 2008 |
CD34 expression is associated with major adverse prognostic factors in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Amsacrine; Aneuploidy; Antibiotics, Antineoplastic; Antigens, CD; Antigens, | 1995 |
Application of fluorescence in situ hybridisation to study the relationship between cytotoxicity, chromosome aberrations, and changes in chromosome number after treatment with the topoisomerase II inhibitor amsacrine.
Topics: Amsacrine; Analysis of Variance; Aneuploidy; Animals; Antineoplastic Agents; Cell Cycle; Cell Divisi | 1996 |