Page last updated: 2024-10-22

amsacrine and Acute Liver Injury, Drug-Induced

amsacrine has been researched along with Acute Liver Injury, Drug-Induced in 9 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Kell, WJ1
Burnett, AK1
Chopra, R1
Yin, JA1
Clark, RE1
Rohatiner, A1
Culligan, D1
Hunter, A1
Prentice, AG1
Milligan, DW1
Tan, RM1
Quah, TC1
Aung, L1
Liang, S1
Kirk, RC1
Yeoh, AE1
Goldsmith, MA1
Bhardwaj, S1
Ohnuma, T1
Greenspan, EM1
Holland, JF1
Arlin, ZA1
Flomenberg, N1
Gee, TS1
Kempin, SJ1
Dellaquila, C1
Mertelsmann, R1
Straus, DJ1
Young, CW1
Clarkson, BD1
Dhaliwal, HS1
Shannon, MS1
Barnett, MJ1
Prentice, HG1
Bragman, K1
Malpas, JS1
Lister, TA1

Trials

1 trial available for amsacrine and Acute Liver Injury, Drug-Induced

ArticleYear
A feasibility study of simultaneous administration of gemtuzumab ozogamicin with intensive chemotherapy in induction and consolidation in younger patients with acute myeloid leukemia.
    Blood, 2003, Dec-15, Volume: 102, Issue:13

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aminoglycosides; Amsacrine; Antibodies, Monoclonal; A

2003

Other Studies

8 other studies available for amsacrine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and

2007
Phase I study of m-AMSA in patients with solid tumors and leukemias.
    Cancer clinical trials, 1980,Fall, Volume: 3, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Chemical and Drug Induced Liver I

1980
Treatment of acute leukemia in relapse with 4'(9-acridinylamino) methanesulfon-m-anisidide (AMSA) in combination with cytosine arabinoside and thioguanine.
    Cancer clinical trials, 1981,Fall, Volume: 4, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Chemical a

1981
Treatment of acute leukaemia with m-AMSA in combination with cytosine arabinoside.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:1

    Topics: Aged; Amsacrine; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Gastrointestinal Diseas

1986