amsacrine has been researched along with Acute Liver Injury, Drug-Induced in 9 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (33.33) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (22.22) | 29.6817 |
2010's | 4 (44.44) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fourches, D | 1 |
Barnes, JC | 1 |
Day, NC | 1 |
Bradley, P | 1 |
Reed, JZ | 1 |
Tropsha, A | 1 |
Liu, Z | 1 |
Shi, Q | 1 |
Ding, D | 1 |
Kelly, R | 1 |
Fang, H | 1 |
Tong, W | 1 |
Sakatis, MZ | 1 |
Reese, MJ | 1 |
Harrell, AW | 1 |
Taylor, MA | 1 |
Baines, IA | 1 |
Chen, L | 1 |
Bloomer, JC | 1 |
Yang, EY | 1 |
Ellens, HM | 1 |
Ambroso, JL | 1 |
Lovatt, CA | 1 |
Ayrton, AD | 1 |
Clarke, SE | 1 |
Morgan, RE | 1 |
van Staden, CJ | 1 |
Chen, Y | 1 |
Kalyanaraman, N | 1 |
Kalanzi, J | 1 |
Dunn, RT | 1 |
Afshari, CA | 1 |
Hamadeh, HK | 1 |
Kell, WJ | 1 |
Burnett, AK | 1 |
Chopra, R | 1 |
Yin, JA | 1 |
Clark, RE | 1 |
Rohatiner, A | 1 |
Culligan, D | 1 |
Hunter, A | 1 |
Prentice, AG | 1 |
Milligan, DW | 1 |
Tan, RM | 1 |
Quah, TC | 1 |
Aung, L | 1 |
Liang, S | 1 |
Kirk, RC | 1 |
Yeoh, AE | 1 |
Goldsmith, MA | 1 |
Bhardwaj, S | 1 |
Ohnuma, T | 1 |
Greenspan, EM | 1 |
Holland, JF | 1 |
Arlin, ZA | 1 |
Flomenberg, N | 1 |
Gee, TS | 1 |
Kempin, SJ | 1 |
Dellaquila, C | 1 |
Mertelsmann, R | 1 |
Straus, DJ | 1 |
Young, CW | 1 |
Clarkson, BD | 1 |
Dhaliwal, HS | 1 |
Shannon, MS | 1 |
Barnett, MJ | 1 |
Prentice, HG | 1 |
Bragman, K | 1 |
Malpas, JS | 1 |
Lister, TA | 1 |
1 trial available for amsacrine and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
A feasibility study of simultaneous administration of gemtuzumab ozogamicin with intensive chemotherapy in induction and consolidation in younger patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aminoglycosides; Amsacrine; Antibodies, Monoclonal; A | 2003 |
8 other studies available for amsacrine and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and | 2007 |
Phase I study of m-AMSA in patients with solid tumors and leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Chemical and Drug Induced Liver I | 1980 |
Treatment of acute leukemia in relapse with 4'(9-acridinylamino) methanesulfon-m-anisidide (AMSA) in combination with cytosine arabinoside and thioguanine.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Chemical a | 1981 |
Treatment of acute leukaemia with m-AMSA in combination with cytosine arabinoside.
Topics: Aged; Amsacrine; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Gastrointestinal Diseas | 1986 |