amrinone has been researched along with Pulmonary Embolism in 3 studies
Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.
Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amrinone, an inotrope with vasodilating properties, is of potential use in managing the right ventricular failure and pulmonary vasoconstriction induced by massive pulmonary embolism (PE)." | 7.68 | Hemodynamic effects of amrinone in a canine model of massive pulmonary embolism. ( Saad, RM; Spence, TH; Wolfe, MW, 1992) |
| "Amrinone, an inotrope with vasodilating properties, is of potential use in managing the right ventricular failure and pulmonary vasoconstriction induced by massive pulmonary embolism (PE)." | 3.68 | Hemodynamic effects of amrinone in a canine model of massive pulmonary embolism. ( Saad, RM; Spence, TH; Wolfe, MW, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Layish, DT | 1 |
| Tapson, VF | 1 |
| Wolfe, MW | 1 |
| Saad, RM | 1 |
| Spence, TH | 2 |
| Newton, WD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism[NCT03988842] | Phase 4 | 4 participants (Actual) | Interventional | 2019-07-25 | Terminated (stopped due to COVID-19 pandemic) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amrinone and Pulmonary Embolism
| Article | Year |
|---|---|
Pharmacologic hemodynamic support in massive pulmonary embolism.
Topics: Amrinone; Animals; Cardiotonic Agents; Dobutamine; Dopamine; Epinephrine; Hemodynamics; Humans; Isop | 1997 |
2 other studies available for amrinone and Pulmonary Embolism
| Article | Year |
|---|---|
Hemodynamic effects of amrinone in a canine model of massive pulmonary embolism.
Topics: Amrinone; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Pulmonary Artery; | 1992 |
Pulmonary embolism: improvement in hemodynamic function with amrinone therapy.
Topics: Amrinone; Coronary Artery Bypass; Hemodynamics; Humans; Male; Middle Aged; Pulmonary Embolism; Time | 1989 |