amrinone has been researched along with Kidney Failure, Chronic in 4 studies
Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amrinone has potent inodilator effects because of its dual mechanism of action." | 2.68 | [Hemodynamic effects of amrinone combined with dopamine in patients undergoing living renal transplantation]. ( Hagihira, S; Inagaki, Y; Mashimo, T; Mori, T; Okuno, Y; Takashina, M; Yoshiya, I, 1997) |
| " We found a shift in the dose-response curve of only phosphodiesterase 5 inhibitors." | 1.32 | The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips. ( Bagcivan, I; Gokce, G; Kilicarslan, H; Sarac, B; Sarioglu, Y; Yildirim, S, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kilicarslan, H | 1 |
| Yildirim, S | 1 |
| Bagcivan, I | 1 |
| Gokce, G | 1 |
| Sarac, B | 1 |
| Sarioglu, Y | 1 |
| Okuno, Y | 1 |
| Mashimo, T | 1 |
| Takashina, M | 1 |
| Hagihira, S | 1 |
| Inagaki, Y | 1 |
| Mori, T | 1 |
| Yoshiya, I | 1 |
| De Vecchis, R | 1 |
| Pucciarelli, G | 1 |
| Nocerino, L | 1 |
| Cocozza, M | 1 |
| Setaro, A | 1 |
| Torre, G | 1 |
| Imperatore, F | 1 |
| Stengele, E | 1 |
| Trenk, D | 1 |
1 trial available for amrinone and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Hemodynamic effects of amrinone combined with dopamine in patients undergoing living renal transplantation].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Amrinone; Cyclic Nucleotide Phosphodiesterases, Type 3; | 1997 |
3 other studies available for amrinone and Kidney Failure, Chronic
| Article | Year |
|---|---|
The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips.
Topics: Amrinone; Animals; Body Weight; Calcium; Creatinine; Dose-Response Relationship, Drug; Electric Stim | 2003 |
[The dobutamine-dopamine combination versus amrinone in congestive heart failure with a marked edematogenic sign complicated by functional kidney failure. A comparison between 2 different models of inotropic stimulation and diuresis potentiation].
Topics: Aged; Amrinone; Cardiotonic Agents; Diuresis; Dobutamine; Dopamine; Drug Evaluation; Drug Therapy, C | 1998 |
[Use of amrinone in terminal dialysis-dependent renal failure].
Topics: Aged; Amrinone; Electrocardiography; Heart Failure; Hemodynamics; Humans; Kidney Failure, Chronic; M | 1992 |