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amrinone and Injury, Ischemia-Reperfusion

amrinone has been researched along with Injury, Ischemia-Reperfusion in 9 studies

Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"The effects of amrinone, a selective phosphodiesterase III inhibitor, on liver ischaemia reperfusion injury have not yet been clarified."9.09Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1. ( Chang, K; Hanaoka, K; Hayashida, M; Makuuchi, M; Orii, R; Sugawara, Y; Takayama, T; Yamada, Y, 2000)
"The present study was designed to investigate the effect of amrinone, a phosphodiesterase III inhibitor, on hepatic ischemia-reperfusion injury in rats."7.71Effects of amrinone on hepatic ischemia-reperfusion injury in rats. ( Imamura, H; Kobayashi, T; Makuuchi, M; Ohkubo, T; Sugawara, Y, 2002)
"Amrinone was found to be effective in preventing intestinal I/R injury."5.33Effect of amrinone on mucosal permeability in experimental intestinal ischaemia/reperfusion injury. ( Ayayvaci, S; Basaklar, AC; Demirogullari, B; Ekingen, G; Kale, N; Karabulut, R; Ozen, O; Sönmez, K; Türkyilmaz, Z; Yenidünya, S, 2005)
"The effects of amrinone, a selective phosphodiesterase III inhibitor, on liver ischaemia reperfusion injury have not yet been clarified."5.09Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1. ( Chang, K; Hanaoka, K; Hayashida, M; Makuuchi, M; Orii, R; Sugawara, Y; Takayama, T; Yamada, Y, 2000)
"Administration of amrinone or NKH477 maintained hepatic tissue concentrations of cyclic nucleotides, and attenuated ischemia and reperfusion injury of the liver."3.71Role of cyclic nucleotides in ischemia and reperfusion injury of canine livers. ( Fujita, M; Furukawa, H; Horiuchi, H; Ishikawa, H; Jin, MB; Magata, S; Masuko, H; Ogata, K; Ogata, T; Shimamura, T; Suzuki, T; Taniguchi, M; Todo, S, 2002)
"The present study was designed to investigate the effect of amrinone, a phosphodiesterase III inhibitor, on hepatic ischemia-reperfusion injury in rats."3.71Effects of amrinone on hepatic ischemia-reperfusion injury in rats. ( Imamura, H; Kobayashi, T; Makuuchi, M; Ohkubo, T; Sugawara, Y, 2002)
"Amrinone has protections against lung I/R injury, possibly through its anti-oxidation effects and an inhibition of inflammation factors releasing."1.34[Protection of amrinone against lung injury induced by ischemia/reperfusion in rats]. ( Gong, SG; Liu, JM, 2007)
"Amrinone was found to be effective in preventing intestinal I/R injury."1.33Effect of amrinone on mucosal permeability in experimental intestinal ischaemia/reperfusion injury. ( Ayayvaci, S; Basaklar, AC; Demirogullari, B; Ekingen, G; Kale, N; Karabulut, R; Ozen, O; Sönmez, K; Türkyilmaz, Z; Yenidünya, S, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (88.89)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kobayashi, T2
Karabulut, R2
Sönmez, K2
Sancak, B1
Türkyilmaz, Z2
Demiroğullari, B2
Ozen, IO1
Ekingen, G2
Candan, S1
Başaklar, AC2
Kale, N2
Ozen, O1
Yenidünya, S1
Ayayvaci, S1
Yoo, KY1
Kim, H1
Jeong, CW1
Park, HC1
Bae, HB1
Lee, J1
Gong, SG1
Liu, JM1
Kucuk, C1
Akcan, A1
Akyýldýz, H1
Akgun, H1
Muhtaroglu, S1
Sozuer, E1
Orii, R1
Sugawara, Y2
Hayashida, M1
Yamada, Y1
Chang, K1
Takayama, T1
Makuuchi, M2
Hanaoka, K1
Ishikawa, H1
Jin, MB1
Ogata, T1
Taniguchi, M1
Suzuki, T1
Shimamura, T1
Magata, S1
Horiuchi, H1
Ogata, K1
Masuko, H1
Fujita, M1
Furukawa, H1
Todo, S1
Ohkubo, T1
Imamura, H1

Trials

1 trial available for amrinone and Injury, Ischemia-Reperfusion

ArticleYear
Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1.
    British journal of anaesthesia, 2000, Volume: 85, Issue:3

    Topics: Aged; Alprostadil; Amrinone; Analysis of Variance; Female; Hepatectomy; Humans; Indocyanine Green; L

2000

Other Studies

8 other studies available for amrinone and Injury, Ischemia-Reperfusion

ArticleYear
A phosphodiesterase III inhibitor protects rat liver from sinusoidal obstruction syndrome through heme oxygenase-1 induction.
    Annals of surgery, 2010, Volume: 251, Issue:4

    Topics: Amrinone; Animals; Heme Oxygenase-1; Hepatectomy; Hepatic Veno-Occlusive Disease; Imidazoles; Phosph

2010
Effects of amrinone on bilateral renal ischemia/reperfusion injury.
    Urological research, 2002, Volume: 30, Issue:3

    Topics: Amrinone; Animals; Blood Urea Nitrogen; Creatinine; Dose-Response Relationship, Drug; Ischemia; Isom

2002
Effect of amrinone on mucosal permeability in experimental intestinal ischaemia/reperfusion injury.
    ANZ journal of surgery, 2005, Volume: 75, Issue:7

    Topics: Amrinone; Animals; Intestinal Diseases; Intestinal Mucosa; Models, Animal; Permeability; Phosphodies

2005
Effects of inotropic drugs on mechanical function and oxygen balance in postischemic canine myocardium: comparison of dobutamine, epinephrine, amrinone, and calcium chloride.
    Journal of Korean medical science, 2005, Volume: 20, Issue:5

    Topics: Amrinone; Animals; Calcium Chloride; Cardiotonic Agents; Dobutamine; Dogs; Dose-Response Relationshi

2005
[Protection of amrinone against lung injury induced by ischemia/reperfusion in rats].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2007, Volume: 9, Issue:3

    Topics: Amrinone; Animals; Interleukin-1beta; Interleukin-8; Lung; Male; Malondialdehyde; Phosphodiesterase

2007
Effects of amrinone in an experimental model of hepatic ischemia-reperfusion injury.
    The Journal of surgical research, 2009, Volume: 151, Issue:1

    Topics: Adenosine Triphosphate; Alanine Transaminase; Amrinone; Animals; Aspartate Aminotransferases; Biopsy

2009
Role of cyclic nucleotides in ischemia and reperfusion injury of canine livers.
    Transplantation, 2002, Apr-15, Volume: 73, Issue:7

    Topics: Adenosine Triphosphate; Amrinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Energy Metabolis

2002
Effects of amrinone on hepatic ischemia-reperfusion injury in rats.
    Journal of hepatology, 2002, Volume: 37, Issue:1

    Topics: Alanine Transaminase; Amrinone; Animals; Aspartate Aminotransferases; Blotting, Western; Cyclic AMP;

2002