amrinone has been researched along with Hypotension in 7 studies
Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidence of amrinone-induced thrombocytopenia has been reported to be 2." | 7.68 | Pancytopenia secondary to short-term, high-dose intravenous infusion of amrinone. ( Burnette, PK; Manny, RP; Mattingly, PM; Weston, MW, 1990) |
| "Clinical trials of intravenous amrinone were performed in 462 patients severely ill with congestive heart failure." | 5.05 | Clinical safety of intravenous amrinone--a review. ( Treadway, G, 1985) |
| "The incidence of amrinone-induced thrombocytopenia has been reported to be 2." | 3.68 | Pancytopenia secondary to short-term, high-dose intravenous infusion of amrinone. ( Burnette, PK; Manny, RP; Mattingly, PM; Weston, MW, 1990) |
| "We gave intravenous amrinone to 40 patients in heart failure, and oral amrinone to 18 patients." | 3.66 | Side effects of amrinone therapy. ( Webb-Peploe, MM; Wilsmhurst, PT, 1983) |
| " Vasodilator therapy generally fails to reduce pulmonary vascular resistance selectively during long-term administration and frequently leads to systemic hypotension, exacerbation of the pulmonary hypertensive state, worsening of right ventricular failure, and systemic arterial desaturation." | 2.37 | Vasodilator therapy for primary pulmonary hypertension. Limitations and hazards. ( Packer, M, 1985) |
| "Amrinone and glucagon have been used separately and in combination with other agents in the treatment of calcium channel blocker overdose." | 1.29 | Use of amrinone and glucagon in a case of calcium channel blocker overdose. ( Otten, EJ; Spadafora, MP; Wolf, LR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilsmhurst, PT | 1 |
| Webb-Peploe, MM | 1 |
| Love, JN | 1 |
| Leasure, JA | 1 |
| Mundt, DJ | 1 |
| Wolf, LR | 1 |
| Spadafora, MP | 1 |
| Otten, EJ | 1 |
| Tuncok, Y | 1 |
| Apaydin, S | 1 |
| Kalkan, S | 1 |
| Ates, M | 1 |
| Guven, H | 1 |
| Mattingly, PM | 1 |
| Burnette, PK | 1 |
| Weston, MW | 1 |
| Manny, RP | 1 |
| Packer, M | 1 |
| Treadway, G | 1 |
1 review available for amrinone and Hypotension
| Article | Year |
|---|---|
Vasodilator therapy for primary pulmonary hypertension. Limitations and hazards.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Aminopyridines; Amrinone; Blood Pressure; Ca | 1985 |
1 trial available for amrinone and Hypotension
| Article | Year |
|---|---|
Clinical safety of intravenous amrinone--a review.
Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Clinical Trials as Topic; Drug I | 1985 |
5 other studies available for amrinone and Hypotension
| Article | Year |
|---|---|
Side effects of amrinone therapy.
Topics: Administration, Oral; Adult; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Female; Heart Failu | 1983 |
A comparison of combined amrinone and glucagon therapy to glucagon alone for cardiovascular depression associated with propranolol toxicity in a canine model.
Topics: Amrinone; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Depression, Chemical; Dogs; | 1993 |
Use of amrinone and glucagon in a case of calcium channel blocker overdose.
Topics: Adult; Amrinone; Drug Overdose; Drug Therapy, Combination; Female; Glucagon; Humans; Hypotension; Ve | 1993 |
The effects of amrinone and glucagon on verapamil-induced cardiovascular toxicity in anaesthetized rats.
Topics: Amrinone; Animals; Blood Pressure; Bradycardia; Calcium Channel Blockers; Cardiovascular Diseases; D | 1996 |
Pancytopenia secondary to short-term, high-dose intravenous infusion of amrinone.
Topics: Amrinone; Bone Marrow; Dopamine; Heart Failure; Humans; Hypotension; Infusions, Intravenous; Male; M | 1990 |