amrinone has been researched along with Heart Disease, Ischemic in 10 studies
Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myocardial ischemia was induced by left coronary artery branch occlusion and quantitated from epicardial NADH-fluorescence photography." | 5.29 | Effect of amrinone and milrinone on myocardial ischemia extent and infarct size in isolated rabbit hearts. ( Blazincic, B; Klaus, W; Rump, AF, 1993) |
| "Amrinone produced an increase in CO comparable to that of OPC-18790; however, the increase in peak LVdP/dt was smaller while the increase in HR and decrease in mBP were larger than those seen with OPC-18790." | 1.29 | Effects of OPC-18790, a new positive inotropic agent, on energetics in the ischaemic canine heart: a 31P-MRS study. ( Fujiki, H; Ishikawa, M; Itoh, S; Koga, K; Mori, T; Tominaga, M; Yabuuchi, Y, 1995) |
| "Myocardial ischemia was induced by left coronary artery branch occlusion and quantitated from epicardial NADH-fluorescence photography." | 1.29 | Effect of amrinone and milrinone on myocardial ischemia extent and infarct size in isolated rabbit hearts. ( Blazincic, B; Klaus, W; Rump, AF, 1993) |
| "Amrinone did not produce significant increases in preload recruitable stroke work area at 0." | 1.29 | The effects of amrinone versus dobutamine on myocardial mechanics and energetics after hypothermic global ischemia. ( Berman, K; Fahey, AL; Isom, OW; Ko, W; Krieger, KH; Lang, D; Zelano, JA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, M | 2 |
| Mori, T | 2 |
| Itoh, S | 2 |
| Fujiki, H | 1 |
| Koga, K | 2 |
| Tominaga, M | 2 |
| Yabuuchi, Y | 2 |
| Massardo, T | 1 |
| Maiers, E | 1 |
| Zamorano, J | 1 |
| Berr, ML | 1 |
| Ayala, F | 1 |
| Ramírez, A | 1 |
| Arriagada, M | 1 |
| González, P | 1 |
| Alliende, I | 1 |
| Rump, AF | 3 |
| Acar, D | 1 |
| Klaus, W | 3 |
| Watanabe, N | 1 |
| Maekawa, K | 1 |
| Nakase, A | 1 |
| Ookawa, Y | 1 |
| Tanaka, A | 1 |
| Satoh, T | 1 |
| Umami, T | 1 |
| Blazincic, B | 1 |
| Tse, J | 1 |
| Cimini, C | 1 |
| Kedem, J | 1 |
| Rodriquez, E | 1 |
| Gonzalez, M | 1 |
| Weiss, HR | 1 |
| Rösen, R | 1 |
| Sigmund, B | 1 |
| Fuchs, J | 1 |
| Dhein, S | 1 |
| Sidi, A | 1 |
| Pool, JM | 1 |
| Rush, W | 1 |
| Ko, W | 1 |
| Zelano, JA | 1 |
| Fahey, AL | 1 |
| Berman, K | 1 |
| Lang, D | 1 |
| Isom, OW | 1 |
| Krieger, KH | 1 |
10 other studies available for amrinone and Heart Disease, Ischemic
| Article | Year |
|---|---|
Effects of OPC-18790, a new positive inotropic agent, on energetics in the ischaemic canine heart: a 31P-MRS study.
Topics: Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Coronary Circulation; Dogs; Dose-Response Rel | 1995 |
Differential effects of OPC-18790, amrinone and dobutamine on cardiac function and energy metabolism in the guinea-pig isolated ischaemic heart.
Topics: Adenosine Triphosphate; Amrinone; Animals; Cardiac Pacing, Artificial; Cardiotonic Agents; Coronary | 1995 |
[Tomographic myocardial perfusion (SPECT) using 99mTc sestamibi-dipyridamole and 2-d-echocardiography with amrinone pre and post myocardial revascularization in 2 cases].
Topics: Amrinone; Coronary Angiography; Coronary Disease; Dipyridamole; Echocardiography; Follow-Up Studies; | 1994 |
A quantitative comparison of functional and anti-ischaemic effects of the phosphodiesterase-inhibitors, amrinone, milrinone and levosimendan in rabbit isolated hearts.
Topics: Amrinone; Animals; Cardiotonic Agents; Coronary Circulation; Electric Stimulation; Heart; Heart Rate | 1994 |
[Hemodynamic effects of Amrinone in patients following open heart surgery].
Topics: Adolescent; Adult; Aged; Amrinone; Cardiac Surgical Procedures; Female; Hemodynamics; Humans; Male; | 1994 |
Effect of amrinone and milrinone on myocardial ischemia extent and infarct size in isolated rabbit hearts.
Topics: Amrinone; Animals; Cardiotonic Agents; Coronary Circulation; Fluorescence; Hemodynamics; Histocytoch | 1993 |
Role of ischemia-reperfusion on myocardial cyclic AMP and cyclic AMP phosphodiesterase: effects of amrinone on regional myocardial force and shortening.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amrinone; Animals; Blood Pressure; Coronary Vessels; Cyclic AMP | 1993 |
Beneficial effect of amrinone on the size of acute regional ischemia in isolated rabbit hearts.
Topics: Amrinone; Animals; Blood Pressure; Coronary Circulation; Fluorescence; Histocytochemistry; In Vitro | 1993 |
Early administration of amrinone does not impair regional metabolism of O2 or lactate and, by improving myocardial performance, preserves myocardial blood flow in the ischemic canine heart.
Topics: Amrinone; Animals; Coronary Circulation; Dogs; Female; Heart; Lactates; Male; Myocardial Ischemia; O | 1993 |
The effects of amrinone versus dobutamine on myocardial mechanics and energetics after hypothermic global ischemia.
Topics: Amrinone; Animals; Coronary Vessels; Dobutamine; Dogs; Hypothermia, Induced; In Vitro Techniques; My | 1993 |