amrinone has been researched along with Cardiomyopathy, Dilated in 17 studies
Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.
Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hemodynamic measurements were done in 42 patients with congestive heart failure of NYHA classes III and IV after administration of the phosphodiesterase inhibitors amrinone und enoximone." | 9.07 | [The hemodynamic profile of amrinone and enoximone in patients with severe heart failure]. ( Peters, P; Saborowski, F; Schneider, M, 1991) |
| "A prospective randomized study was performed in 46 consecutive patients with refractory congestive heart failure (CHF) due to idiopathic dilated cardiomyopathy to compare the hemodynamic responses to 48-hour infusions of amrinone and dobutamine." | 9.06 | Comparison of intravenous amrinone and dobutamine in congestive heart failure due to idiopathic dilated cardiomyopathy. ( Marcus, RH; Mitha, A; Patel, J; Raw, K; Sareli, P, 1990) |
| "The hemodynamic response to amrinone was analyzed in 19 patients with severe heart failure (NYHA III or IV)." | 7.68 | [The hemodynamic profile of the response to amrinone treatment in severe heart failure]. ( Altimiras Ruiz, J; Bayés de Luna, A; Binia Mizrahi, M; Domínguez de Rozas, J; García Picart, J; Guindo Soldevila, J; Pastor Ramón, E, 1991) |
| "The effects of intravenous amrinone and sodium nitroprusside on haemodynamic indices, left ventricular contractility, and myocardial metabolism were compared in patients with cardiac failure." | 7.67 | Comparison of the effects of amrinone and sodium nitroprusside on haemodynamics, contractility, and myocardial metabolism in patients with cardiac failure due to coronary artery disease and dilated cardiomyopathy. ( Coltart, DJ; Jenkins, BS; Juul, SM; Thompson, DS; Webb-Peploe, MM; Wilmshurst, PT, 1984) |
| "Hemodynamic measurements were done in 42 patients with congestive heart failure of NYHA classes III and IV after administration of the phosphodiesterase inhibitors amrinone und enoximone." | 5.07 | [The hemodynamic profile of amrinone and enoximone in patients with severe heart failure]. ( Peters, P; Saborowski, F; Schneider, M, 1991) |
| "A prospective randomized study was performed in 46 consecutive patients with refractory congestive heart failure (CHF) due to idiopathic dilated cardiomyopathy to compare the hemodynamic responses to 48-hour infusions of amrinone and dobutamine." | 5.06 | Comparison of intravenous amrinone and dobutamine in congestive heart failure due to idiopathic dilated cardiomyopathy. ( Marcus, RH; Mitha, A; Patel, J; Raw, K; Sareli, P, 1990) |
| "The hemodynamic response to amrinone was analyzed in 19 patients with severe heart failure (NYHA III or IV)." | 3.68 | [The hemodynamic profile of the response to amrinone treatment in severe heart failure]. ( Altimiras Ruiz, J; Bayés de Luna, A; Binia Mizrahi, M; Domínguez de Rozas, J; García Picart, J; Guindo Soldevila, J; Pastor Ramón, E, 1991) |
| "The effects of intravenous amrinone and sodium nitroprusside on haemodynamic indices, left ventricular contractility, and myocardial metabolism were compared in patients with cardiac failure." | 3.67 | Comparison of the effects of amrinone and sodium nitroprusside on haemodynamics, contractility, and myocardial metabolism in patients with cardiac failure due to coronary artery disease and dilated cardiomyopathy. ( Coltart, DJ; Jenkins, BS; Juul, SM; Thompson, DS; Webb-Peploe, MM; Wilmshurst, PT, 1984) |
| " Attempts to support cardiovascular function by high-dose dobutamine infusions were complicated by life-threatening cardiac arrhythmias." | 3.67 | Augmentation of cardiac function in end-stage heart failure by combined use of dobutamine and amrinone. ( Guimond, JG; Keating, D; Matuschak, GM; Meyers, F, 1986) |
| "Nine consecutive patients having severe idiopathic dilated cardiomyopathy were studied for their response in ventricular function, coronary sinus blood flow and myocardial oxygen consumption, lactate extraction and efficiency following incremental doses of dobutamine, followed by the combination of dobutamine and the phosphodiesterase inhibitor amrinone." | 1.28 | Myocardial energetics and efficiency in patients with idiopathic cardiomyopathy: response to dobutamine and amrinone. ( Janicki, JS; McElroy, PA; Reddy, HK; Sundram, P; Weber, KT, 1990) |
| ") in combination with dobutamine and dopamine." | 1.28 | [Successful use of amrinone in combination with dobutamine in the treatment of severe heart failure]. ( Firt, P; Málek, I; Vojtísková, J, 1989) |
| "Thus, in patients with idiopathic dilated cardiomyopathy, administration of amrinone has a complex effect on LV diastolic properties." | 1.28 | Comparison of Doppler indexes of left ventricular diastolic function with simultaneous high fidelity left atrial and ventricular pressures in idiopathic dilated cardiomyopathy. ( Borow, KM; David, D; Lang, RM; Marcus, R; Neumann, A; Sareli, P; Spencer, KT, 1989) |
| "Amrinone, a new inotropic drug, was infused at a dosage of 2." | 1.27 | Echocardiographic evaluation of cardiovascular effects of amrinone. ( Benassi, A; Mattioli, G; Modena, MG, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (58.82) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Modena, MG | 1 |
| Benassi, A | 1 |
| Mattioli, G | 2 |
| Kark, P | 1 |
| Gillmer, DJ | 1 |
| Wilmshurst, PT | 2 |
| Thompson, DS | 2 |
| Juul, SM | 2 |
| Jenkins, BS | 2 |
| Coltart, DJ | 2 |
| Webb-Peploe, MM | 2 |
| Takeuchi, M | 1 |
| Sonoda, S | 1 |
| Himeno, E | 1 |
| Tanaka, S | 1 |
| Okazaki, M | 1 |
| Nakashima, Y | 1 |
| Kuroiwa, A | 1 |
| Iskandrian, AE | 1 |
| Nakajima, Y | 1 |
| Hayashi, Y | 1 |
| Miyashita, T | 1 |
| Horinouchi, N | 1 |
| Ohnishi, Y | 1 |
| Kuro, M | 1 |
| Saborowski, F | 1 |
| Peters, P | 1 |
| Schneider, M | 1 |
| Domínguez de Rozas, J | 1 |
| García Picart, J | 1 |
| Guindo Soldevila, J | 1 |
| Altimiras Ruiz, J | 1 |
| Binia Mizrahi, M | 1 |
| Pastor Ramón, E | 1 |
| Bayés de Luna, A | 1 |
| Marcus, RH | 1 |
| Raw, K | 1 |
| Patel, J | 1 |
| Mitha, A | 1 |
| Sareli, P | 2 |
| Sundram, P | 1 |
| Reddy, HK | 1 |
| McElroy, PA | 1 |
| Janicki, JS | 1 |
| Weber, KT | 1 |
| Vojtísková, J | 1 |
| Málek, I | 1 |
| Firt, P | 1 |
| David, D | 1 |
| Lang, RM | 1 |
| Neumann, A | 1 |
| Marcus, R | 1 |
| Spencer, KT | 1 |
| Borow, KM | 1 |
| Cappello, C | 1 |
| Fusaro, MT | 1 |
| Thormann, J | 1 |
| Kramer, W | 1 |
| Kindler, M | 1 |
| Kremer, P | 1 |
| Schlepper, M | 1 |
| Guimond, JG | 1 |
| Matuschak, GM | 1 |
| Meyers, F | 1 |
| Keating, D | 1 |
| Klepzig, M | 1 |
| Kleinhans, E | 1 |
| Büll, U | 1 |
| Strauer, BE | 1 |
| Dittrich, HC | 1 |
| Dawson, JR | 1 |
| Walker, JM | 1 |
2 trials available for amrinone and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
[The hemodynamic profile of amrinone and enoximone in patients with severe heart failure].
Topics: Aged; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Disease; Dobutamine; Dopamine; | 1991 |
Comparison of intravenous amrinone and dobutamine in congestive heart failure due to idiopathic dilated cardiomyopathy.
Topics: Adult; Amrinone; Cardiomyopathy, Dilated; Dobutamine; Female; Heart Failure; Hemodynamics; Humans; I | 1990 |
15 other studies available for amrinone and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Echocardiographic evaluation of cardiovascular effects of amrinone.
Topics: Adult; Aminopyridines; Amrinone; Cardiac Catheterization; Cardiomyopathy, Dilated; Cardiotonic Agent | 1984 |
Dangers of amrinone.
Topics: Aminopyridines; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Heart Failure; Humans | 1984 |
Comparison of the effects of amrinone and sodium nitroprusside on haemodynamics, contractility, and myocardial metabolism in patients with cardiac failure due to coronary artery disease and dilated cardiomyopathy.
Topics: Adult; Aminopyridines; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Disease; Fema | 1984 |
Comparative effects of dobutamine and amrinone on coronary blood flow in patients with idiopathic dilated cardiomyopathy.
Topics: Adult; Aged; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Circulation; Dobutamine | 1997 |
Coronary blood flow in patients with idiopathic dilated cardiomyopathy.
Topics: Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Circulation; Dobutamine; Humans | 1997 |
[Anesthetic management of patients undergoing implantation of left ventricular assist system].
Topics: Adolescent; Adult; Amrinone; Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiomyopathy, Dila | 1999 |
[The hemodynamic profile of the response to amrinone treatment in severe heart failure].
Topics: Amrinone; Cardiomyopathy, Dilated; Drug Evaluation; Female; Heart Failure; Hemodynamics; Humans; Inf | 1991 |
Myocardial energetics and efficiency in patients with idiopathic cardiomyopathy: response to dobutamine and amrinone.
Topics: Amrinone; Cardiomyopathy, Dilated; Dobutamine; Drug Therapy, Combination; Hemodynamics; Humans; Lact | 1990 |
[Successful use of amrinone in combination with dobutamine in the treatment of severe heart failure].
Topics: Amrinone; Cardiomyopathy, Dilated; Dobutamine; Drug Therapy, Combination; Humans; Male; Middle Aged | 1989 |
Comparison of Doppler indexes of left ventricular diastolic function with simultaneous high fidelity left atrial and ventricular pressures in idiopathic dilated cardiomyopathy.
Topics: Adult; Amrinone; Blood Pressure; Cardiomyopathy, Dilated; Diastole; Echocardiography; Echocardiograp | 1989 |
[Congestive cardiomyopathy: basal hemodynamics and hemodynamics after various positive inotropic drugs administered singly or in combinations].
Topics: Adult; Aged; Amrinone; Captopril; Cardiomyopathy, Dilated; Cardiotonic Agents; Deoxyepinephrine; Dig | 1988 |
[Determination of active components of amrinone by analysis of pressure-volume results; use of the conductance (volume) catheter technic and rapid load change by balloon occlusion of the inferior vena cava].
Topics: Amrinone; Cardiac Catheterization; Cardiac Output, Low; Cardiomyopathy, Dilated; Dobutamine; Drug Th | 1987 |
Augmentation of cardiac function in end-stage heart failure by combined use of dobutamine and amrinone.
Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Cardiotonic Agents; Dobutam | 1986 |
[Amrinone in acute and long-term therapy].
Topics: Administration, Oral; Aminopyridines; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronar | 1985 |
Effects of intracoronary and intravenous amrinone infusions in patients with cardiac failure and patients with near normal cardiac function.
Topics: Adult; Aminopyridines; Amrinone; Angina Pectoris; Blood Pressure; Cardiomyopathy, Dilated; Cardioton | 1985 |