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amrinone and Cardiomyopathies

amrinone has been researched along with Cardiomyopathies in 4 studies

Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"The present study compared the effects of amrinone, dobutamine, dibutyryl cAMP, digoxin, and isoproterenol on mechanical performance, the high energy phosphate metabolites, and the [Ca2+]i transients in normal and cardiomyopathic hamster hearts with severe heart failure."3.69Distinct modulation of myocardial performance, energy metabolism, and [Ca2+]i transients by positive inotropic drugs in normal and severely failing hamster hearts. ( Buser, PT; Jasmin, G; Parmley, WW; Wikman-Coffelt, J; Wu, SY, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buser, PT2
Wu, SY1
Parmley, WW2
Jasmin, G2
Wikman-Coffelt, J2
Matsui, S1
Matsumori, A1
Matoba, Y1
Uchida, A1
Sasayama, S1
Lawless, ST1
Zaritsky, A1
Miles, M1
Auffermann, W1
Wu, ST1

Other Studies

4 other studies available for amrinone and Cardiomyopathies

ArticleYear
Distinct modulation of myocardial performance, energy metabolism, and [Ca2+]i transients by positive inotropic drugs in normal and severely failing hamster hearts.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:1

    Topics: Amrinone; Animals; Blood Pressure; Bucladesine; Calcium; Cardiomyopathies; Cardiotonic Agents; Crice

1995
Treatment of virus-induced myocardial injury with a novel immunomodulating agent, vesnarinone. Suppression of natural killer cell activity and tumor necrosis factor-alpha production.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Amrinone; Animals; Cardiomyopathies; Cardiovirus Infections; Encephalomyocarditis virus; Female; Imm

1994
The acute pharmacokinetics and pharmacodynamics of amrinone in pediatric patients.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:9

    Topics: Amrinone; Cardiomyopathies; Child, Preschool; Heart Diseases; Hemodynamics; Humans; Infant; Infant,

1991
Dobutamine potentiates amrinone's beneficial effects in moderate but not in advanced heart failure. 31P-MRS in isolated hamster hearts.
    Circulation research, 1990, Volume: 66, Issue:3

    Topics: Amrinone; Animals; Cardiac Output, Low; Cardiomyopathies; Cricetinae; Dobutamine; Drug Combinations;

1990