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amrinone and Cardiomyopathies, Primary

amrinone has been researched along with Cardiomyopathies, Primary in 4 studies

Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"The present study compared the effects of amrinone, dobutamine, dibutyryl cAMP, digoxin, and isoproterenol on mechanical performance, the high energy phosphate metabolites, and the [Ca2+]i transients in normal and cardiomyopathic hamster hearts with severe heart failure."3.69Distinct modulation of myocardial performance, energy metabolism, and [Ca2+]i transients by positive inotropic drugs in normal and severely failing hamster hearts. ( Buser, PT; Jasmin, G; Parmley, WW; Wikman-Coffelt, J; Wu, SY, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buser, PT2
Wu, SY1
Parmley, WW2
Jasmin, G2
Wikman-Coffelt, J2
Matsui, S1
Matsumori, A1
Matoba, Y1
Uchida, A1
Sasayama, S1
Lawless, ST1
Zaritsky, A1
Miles, M1
Auffermann, W1
Wu, ST1

Other Studies

4 other studies available for amrinone and Cardiomyopathies, Primary

ArticleYear
Distinct modulation of myocardial performance, energy metabolism, and [Ca2+]i transients by positive inotropic drugs in normal and severely failing hamster hearts.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:1

    Topics: Amrinone; Animals; Blood Pressure; Bucladesine; Calcium; Cardiomyopathies; Cardiotonic Agents; Crice

1995
Treatment of virus-induced myocardial injury with a novel immunomodulating agent, vesnarinone. Suppression of natural killer cell activity and tumor necrosis factor-alpha production.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Amrinone; Animals; Cardiomyopathies; Cardiovirus Infections; Encephalomyocarditis virus; Female; Imm

1994
The acute pharmacokinetics and pharmacodynamics of amrinone in pediatric patients.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:9

    Topics: Amrinone; Cardiomyopathies; Child, Preschool; Heart Diseases; Hemodynamics; Humans; Infant; Infant,

1991
Dobutamine potentiates amrinone's beneficial effects in moderate but not in advanced heart failure. 31P-MRS in isolated hamster hearts.
    Circulation research, 1990, Volume: 66, Issue:3

    Topics: Amrinone; Animals; Cardiac Output, Low; Cardiomyopathies; Cricetinae; Dobutamine; Drug Combinations;

1990