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amrinone and Arrhythmia

amrinone has been researched along with Arrhythmia in 17 studies

Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"The use of amrinone, a cardiac inotropic agent with vasodilatory properties, has not been described in human pregnancy."7.68Use of intravenous amrinone in the short-term management of refractory heart failure in pregnancy. ( Bhatia, RK; Ganguly, S; Jelsema, RD, 1991)
"Amrinone, a new inotropic agent, was used to treat 24 patients with chronic congestive heart failure who were classified as clinically stable and who were in New York Heart Association's classes II and III."7.67Clinical effects and side effects of amrinone. A study of 24 patients with chronic congestive heart failure. ( Gerber, L; Merrill, AJ; Silverman, BD, 1985)
"Clinical trials of intravenous amrinone were performed in 462 patients severely ill with congestive heart failure."5.05Clinical safety of intravenous amrinone--a review. ( Treadway, G, 1985)
"5-2% sevoflurane anesthesia, 0."3.69Amrinone is superior to epinephrine in reversing bupivacaine-induced cardiovascular depression in sevoflurane-anesthetized dogs. ( Fukuda, H; Hirabayashi, Y; Saitoh, K; Shimizu, R, 1995)
"The use of amrinone, a cardiac inotropic agent with vasodilatory properties, has not been described in human pregnancy."3.68Use of intravenous amrinone in the short-term management of refractory heart failure in pregnancy. ( Bhatia, RK; Ganguly, S; Jelsema, RD, 1991)
" Attempts to support cardiovascular function by high-dose dobutamine infusions were complicated by life-threatening cardiac arrhythmias."3.67Augmentation of cardiac function in end-stage heart failure by combined use of dobutamine and amrinone. ( Guimond, JG; Keating, D; Matuschak, GM; Meyers, F, 1986)
"Amrinone, a new inotropic agent, was used to treat 24 patients with chronic congestive heart failure who were classified as clinically stable and who were in New York Heart Association's classes II and III."3.67Clinical effects and side effects of amrinone. A study of 24 patients with chronic congestive heart failure. ( Gerber, L; Merrill, AJ; Silverman, BD, 1985)
"Significant proarrhythmia is uncommon, but can occur."1.28Electrophysiology of phosphodiesterase inhibitors. ( Goldstein, RA; Naccarelli, GV, 1989)
"Dobutamine and amrinone were much better tolerated."1.27Comparative vasoactive therapy for heart failure. ( Alpert, JS; Benotti, JR; McCue, JE, 1985)
"Patients with congestive heart failure (CHF) have a high prevalence of complex ventricular arrhythmias."1.27Electrophysiologic effects of amrinone. ( Dougherty, AH; Goldstein, RA; Gray, EL; Naccarelli, GV, 1985)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's4 (23.53)18.2507
2000's1 (5.88)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, Y1
Yuan, J1
Qian, Z1
Zhang, X1
Chen, Y1
Hou, X1
Zou, J1
Ko, Y1
Morita, K1
Nagahori, R1
Kinouchi, K1
Shinohara, G1
Kagawa, H1
Hashimoto, K1
Méndez, R1
Onuaguluchi, G2
Tanz, RD2
McCawley, E1
Saitoh, K1
Hirabayashi, Y1
Shimizu, R1
Fukuda, H1
Trolese-Mongheal, Y1
Barthelemy, J1
Paire, M1
Duchene-Marullaz, P1
Jelsema, RD1
Bhatia, RK1
Ganguly, S1
Xu, D1
Yang, Z1
Naccarelli, GV3
Goldstein, RA3
Tommaso, CL1
Guimond, JG1
Matuschak, GM1
Meyers, F1
Keating, D1
Treadway, G1
Silverman, BD1
Merrill, AJ1
Gerber, L1
Benotti, JR1
McCue, JE1
Alpert, JS1
Gray, EL1
Dougherty, AH1

Reviews

2 reviews available for amrinone and Arrhythmia

ArticleYear
[The old digitalis and the new cardiac inotropic agents].
    Archivos de farmacologia y toxicologia, 1983, Volume: 9, Issue:1

    Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardenolides; Cardiotonic Agents; Digitalis Glycosid

1983
Non-glycoside, non-catecholamine inotropic agents in the treatment of congestive heart failure.
    The American journal of medicine, 1986, Feb-28, Volume: 80, Issue:2B

    Topics: Administration, Oral; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Calcium; Cardiac Output; Cardi

1986

Trials

1 trial available for amrinone and Arrhythmia

ArticleYear
Clinical safety of intravenous amrinone--a review.
    The American journal of cardiology, 1985, Jul-22, Volume: 56, Issue:3

    Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Clinical Trials as Topic; Drug I

1985

Other Studies

14 other studies available for amrinone and Arrhythmia

ArticleYear
β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failure.
    Scientific reports, 2015, Jan-08, Volume: 5

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amrinone; Animals; Arrhythmias, Ca

2015
Myocardial cyclic AMP augmentation with high-dose PDEIII inhibitor in terminal warm blood cardioplegia.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2009, Volume: 15, Issue:5

    Topics: Amrinone; Animals; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Cardiotonic Agents; Coronary Circul

2009
Electromechanical dissociation and possible uncoupling of phosphorylation following tachydysrhythmogenic dose of amrinone in the guinea-pig Langendorff heart preparation.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 271, Issue:1

    Topics: Aminopyridines; Amrinone; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Electrocardiography; Gu

1984
Electrocardiographic changes induced by amrinone in the isolated perfused guinea-pig Langendorff heart preparation.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 264, Issue:2

    Topics: Aminopyridines; Amrinone; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Electrocardiography; Gu

1983
Amrinone is superior to epinephrine in reversing bupivacaine-induced cardiovascular depression in sevoflurane-anesthetized dogs.
    Anesthesiology, 1995, Volume: 83, Issue:1

    Topics: Amrinone; Anesthesia; Anesthetics; Animals; Arrhythmias, Cardiac; Bupivacaine; Dogs; Epinephrine; Et

1995
Arrhythmogenic potencies of amrinone and milrinone in unanesthetized dogs with myocardial infarct.
    General pharmacology, 1992, Volume: 23, Issue:1

    Topics: Amrinone; Analysis of Variance; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Dogs; Heart Rate;

1992
Use of intravenous amrinone in the short-term management of refractory heart failure in pregnancy.
    Obstetrics and gynecology, 1991, Volume: 78, Issue:5 Pt 2

    Topics: Acidosis, Lactic; Adult; Amrinone; Arrhythmias, Cardiac; Endocarditis, Bacterial; Female; Heart Fail

1991
[The effect of China-made amrinone on myocardial infarction and arrhythmia in dogs].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1990, Volume: 21, Issue:4

    Topics: Amrinone; Animals; Arrhythmias, Cardiac; Dogs; Myocardial Contraction; Myocardial Infarction; Stimul

1990
Electrophysiology of phosphodiesterase inhibitors.
    The American journal of cardiology, 1989, Jan-03, Volume: 63, Issue:2

    Topics: Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Electrocardiography; Electrophysiology; Heart Co

1989
Augmentation of cardiac function in end-stage heart failure by combined use of dobutamine and amrinone.
    Chest, 1986, Volume: 90, Issue:2

    Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Cardiotonic Agents; Dobutam

1986
Clinical effects and side effects of amrinone. A study of 24 patients with chronic congestive heart failure.
    Archives of internal medicine, 1985, Volume: 145, Issue:5

    Topics: Adult; Aged; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Chronic Disease; El

1985
Comparative vasoactive therapy for heart failure.
    The American journal of cardiology, 1985, Jul-22, Volume: 56, Issue:3

    Topics: Adult; Aged; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiot

1985
Electrophysiologic effects of amrinone.
    The American journal of cardiology, 1985, Jul-22, Volume: 56, Issue:3

    Topics: Adult; Aged; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiac Output; Cardiac Pacing, Artific

1985
Intravenous amrinone.
    Annals of internal medicine, 1985, Volume: 103, Issue:4

    Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Humans; Infusions, Parenteral

1985