Page last updated: 2024-10-29

amrinone and Aging

amrinone has been researched along with Aging in 3 studies

Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" There was a large variability in the volume of distribution, clearance, and elimination half-life which did not appear to be age-related."1.29Age-related amrinone pharmacokinetics in a pediatric population. ( Allen-Webb, EM; Banner, W; McGough, EC; Pappas, JB; Ross, MP, 1994)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Binah, O1
Legato, MJ1
Danilo, P1
Rosen, MR1
Allen-Webb, EM1
Ross, MP1
Pappas, JB1
McGough, EC1
Banner, W1
Harada, K1
Ohashi, K1
Kumagai, Y1
Ohmori, M1
Fujimura, A1

Trials

1 trial available for amrinone and Aging

ArticleYear
Influence of age on venodilator effect of isoproterenol and amrinone.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Amrinone; Blood Pressure; Cross-Ove

1996

Other Studies

2 other studies available for amrinone and Aging

ArticleYear
Developmental changes in the cardiac effects of amrinone in the dog.
    Circulation research, 1983, Volume: 52, Issue:6

    Topics: Aging; Aminopyridines; Amrinone; Animals; Animals, Newborn; Dogs; Female; Heart Conduction System; M

1983
Age-related amrinone pharmacokinetics in a pediatric population.
    Critical care medicine, 1994, Volume: 22, Issue:6

    Topics: Adolescent; Aging; Amrinone; Child; Child, Preschool; Half-Life; Humans; Infant; Infant, Newborn; In

1994