amrinone has been researched along with Abnormality, Heart in 13 studies
Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "11 infants and children with severe congestive heart failure after cardiac surgery were treated with Amrinone." | 3.67 | [Effects of amrinone in myocardial insufficiency following heart surgery in children]. ( Seiffert, P; Wessel, A, 1989) |
| "Amrinone clearance was 2." | 1.31 | Pharmacokinetics of amrinone in neonates and infants. ( Ahonen, J; Laitinen, P; Olkkola, KT; Peltola, K; Räsänen, J; Rautiainen, P, 2000) |
| "Amrinone was loaded with a dose of 1." | 1.31 | Cardiovascular effects of a phosphodiesterase III inhibitor, amrinone, in infants: non-invasive echocardiographic evaluation. ( Motomura, H; Nakazawa, M; Takeda, A; Teshima, H; Tobita, K; Yamamura, H, 2002) |
| "Amrinone was continuously infused at 10 micrograms/kg/min in 5 patients (Group A), or milrinone was continuously infused at 0." | 1.30 | [Hemodynamic effects of amrinone or milrinone in infant after right heart bypass operation]. ( Fuijmoto, J; Fuijwara, T; Ka, H; Kaneko, Y; Kanemoto, S; Kobayashi, J; Nagata, N; Okabe, H, 1998) |
| "Amrinone was administered, and blood was serially assayed for amrinone levels." | 1.29 | Amrinone loading during cardiopulmonary bypass in neonates, infants, and children. ( Boggs, DP; Lynn, AM; Mulroy, JJ; Oakes, R; Sorensen, GK; Williams, GD, 1995) |
| "Amrinone was used as the sole vasoactive medication in 9 of 14 children (aged 5 months to 8." | 1.29 | Hemodynamic effects of amrinone and colloid administration in children following cardiac surgery. ( Anderson, GD; Lynn, AM; Opheim, KE; Sorensen, GK; Williams, GD, 1993) |
| "Amrinone was administered as a bolus of 1 mg kg-1 body wt." | 1.28 | Hemodynamic effects of amrinone in children after cardiac surgery. ( Berner, M; Friedli, B; Jaccard, C; Oberhansli, I; Rouge, JC, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilmshurst, PT | 1 |
| Walker, JM | 1 |
| Fry, CH | 1 |
| Mounsey, JP | 1 |
| Twort, CH | 1 |
| Williams, BT | 1 |
| Davies, MJ | 1 |
| Webb-Peploe, MM | 1 |
| Williams, GD | 2 |
| Sorensen, GK | 3 |
| Oakes, R | 1 |
| Boggs, DP | 1 |
| Mulroy, JJ | 1 |
| Lynn, AM | 3 |
| Nomura, K | 1 |
| Kurosawa, H | 1 |
| Hashimoto, K | 1 |
| Yamagishi, M | 1 |
| Koyanagi, K | 1 |
| Tanaka, K | 1 |
| Mashiko, K | 1 |
| Nakano, M | 1 |
| Anderson, GD | 1 |
| Opheim, KE | 1 |
| Ramamoorthy, C | 1 |
| French, J | 1 |
| Stevenson, JG | 1 |
| Bailey, JM | 1 |
| Miller, BE | 1 |
| Kanter, KR | 1 |
| Tosone, SR | 1 |
| Tam, VK | 1 |
| Okabe, H | 1 |
| Kaneko, Y | 1 |
| Nagata, N | 1 |
| Kobayashi, J | 1 |
| Kanemoto, S | 1 |
| Ka, H | 1 |
| Fuijmoto, J | 1 |
| Fuijwara, T | 1 |
| Ochiai, Y | 1 |
| Morita, S | 1 |
| Tanoue, Y | 1 |
| Kawachi, Y | 1 |
| Tominaga, R | 1 |
| Yasui, H | 1 |
| Laitinen, P | 1 |
| Ahonen, J | 1 |
| Olkkola, KT | 1 |
| Peltola, K | 1 |
| Rautiainen, P | 1 |
| Räsänen, J | 1 |
| Teshima, H | 1 |
| Tobita, K | 1 |
| Yamamura, H | 1 |
| Takeda, A | 1 |
| Motomura, H | 1 |
| Nakazawa, M | 1 |
| Berner, M | 1 |
| Jaccard, C | 1 |
| Oberhansli, I | 1 |
| Rouge, JC | 1 |
| Friedli, B | 1 |
| Wessel, A | 1 |
| Seiffert, P | 1 |
| Lawless, S | 1 |
| Burckart, G | 1 |
| Diven, W | 1 |
| Thompson, A | 1 |
| Siewers, R | 1 |
1 trial available for amrinone and Abnormality, Heart
| Article | Year |
|---|---|
[Effects of amrinone on left ventricular function following open heart surgery--analysis with left ventricular pressure volume loops].
Topics: Adult; Aged; Amrinone; Cardiac Surgical Procedures; Child; Extracorporeal Circulation; Female; Heart | 1994 |
12 other studies available for amrinone and Abnormality, Heart
| Article | Year |
|---|---|
Inotropic and vasodilator effects of amrinone on isolated human tissue.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Gui | 1984 |
Amrinone loading during cardiopulmonary bypass in neonates, infants, and children.
Topics: Amrinone; Cardiopulmonary Bypass; Child; Child, Preschool; Chromatography, High Pressure Liquid; For | 1995 |
Hemodynamic effects of amrinone and colloid administration in children following cardiac surgery.
Topics: Amrinone; Blood Pressure; Cardiac Output; Child; Child, Preschool; Chromatography, High Pressure Liq | 1993 |
Hemodynamic effects of amrinone in children after Fontan surgery.
Topics: Amrinone; Cardiac Output; Cardiotonic Agents; Child; Child, Preschool; Fontan Procedure; Heart Defec | 1996 |
A comparison of the hemodynamic effects of amrinone and sodium nitroprusside in infants after cardiac surgery.
Topics: Amrinone; Blood Pressure; Cardiac Output; Cardiac Output, Low; Cardiac Surgical Procedures; Cardioto | 1997 |
[Hemodynamic effects of amrinone or milrinone in infant after right heart bypass operation].
Topics: Amrinone; Child; Child, Preschool; Dopamine; Heart Bypass, Right; Heart Defects, Congenital; Hemodyn | 1998 |
Effects of amrinone, a phosphodiesterase inhibitor, on right ventricular/arterial coupling immediately after cardiac operations.
Topics: Adult; Amrinone; Cardiac Output; Cardiac Surgical Procedures; Echocardiography, Transesophageal; Fem | 1998 |
Pharmacokinetics of amrinone in neonates and infants.
Topics: Amrinone; Cardiopulmonary Bypass; Cardiotonic Agents; Female; Half-Life; Heart Defects, Congenital; | 2000 |
Cardiovascular effects of a phosphodiesterase III inhibitor, amrinone, in infants: non-invasive echocardiographic evaluation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amrinone; Cardiac Surgical Procedures; Cardiotonic Agents; Cycl | 2002 |
Hemodynamic effects of amrinone in children after cardiac surgery.
Topics: Adolescent; Amrinone; Cardiac Surgical Procedures; Child; Child, Preschool; Heart Defects, Congenita | 1990 |
[Effects of amrinone in myocardial insufficiency following heart surgery in children].
Topics: Adolescent; Amrinone; Blood Pressure; Cardiac Output; Child; Child, Preschool; Echocardiography; Fem | 1989 |
Amrinone pharmacokinetics in neonates and infants.
Topics: Amrinone; Body Surface Area; Cardiac Output; Cardiopulmonary Bypass; Heart Defects, Congenital; Huma | 1988 |