ampyrone and Hypothermia studies

Ampyrone: A metabolite of AMINOPYRINE with analgesic and anti-inflammatory properties. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates LIVER MICROSOMES and is also used to measure extracellular water.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

Excerpt	Relevance	Reference
"The antipyretic and hypothermic prodrug dipyrone prevents PGE2 -dependent and -independent fever induced by LPS from Escherichia coli and Tityus serrulatus venom (Tsv) respectively."	7.80	Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. ( Aguiar, FA; Assis, DC; Clososki, GC; de Melo, MC; de Souza, GE; Ferreira, SH; Jabor, VA; Kalapothakis, E; Malvar, Ddo C; Vaz, Ade L, 2014)
"The antipyretic and hypothermic prodrug dipyrone prevents PGE2 -dependent and -independent fever induced by LPS from Escherichia coli and Tityus serrulatus venom (Tsv) respectively."	3.80	Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. ( Aguiar, FA; Assis, DC; Clososki, GC; de Melo, MC; de Souza, GE; Ferreira, SH; Jabor, VA; Kalapothakis, E; Malvar, Ddo C; Vaz, Ade L, 2014)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

ampyrone and Hypothermia

Research Excerpts

Research

Studies (1)

Authors

Other Studies

Authors	Studies
Malvar, Ddo C	1
Aguiar, FA	1
Vaz, Ade L	1
Assis, DC	1
de Melo, MC	1
Jabor, VA	1
Kalapothakis, E	1
Ferreira, SH	1
Clososki, GC	1
de Souza, GE	1