amprolium has been researched along with Necrosis in 9 studies
Amprolium: A veterinary coccidiostat that interferes with THIAMINE metabolism.
amprolium : An organic chloride salt having 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium as the counterion. Used for prevention of coccidiosis in poultry and cattle.
amprolium(1+) : A pyridinium ion that is the cationic portion of amprolium, a veterinary drug which is used for prevention of coccidiosis in poultry and cattle.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amprolium was successfully used to induce cerebrocortical necrosis (CCN) in dromedary racing camels, only when they were fed on a barley diet." | 7.70 | Amprolium-induced cerebrocortical necrosis (CCN) in dromedary racing camels. ( Haydn-Evans, J; Kinne, J; Wernery, U, 1998) |
| "Culture of neuroblastoma cells in a medium of low-thiamine concentration (6 nM) and in the presence of the transport inhibitor amprolium leads to the appearance of overt signs of necrosis; i." | 7.69 | Thiamine deficiency--induced partial necrosis and mitochondrial uncoupling in neuroblastoma cells are rapidly reversed by addition of thiamine. ( Bettendorff, L; Goessens, G; Grisar, T; Sluse, F; Wins, P, 1995) |
| "Purposing to get some hints on cause and early diagnosis for cerebrocortical necrosis (CCN), CCN was produced in three healthy calves by the oral administration of amprolium." | 7.67 | Clinical and biochemical findings in bovine cerebrocortical necrosis produced by oral administration of amprolium. ( Ichijo, S; Kasahara, T; Osame, S; Sarashina, T, 1989) |
| "Amprolium was successfully used to induce cerebrocortical necrosis (CCN) in dromedary racing camels, only when they were fed on a barley diet." | 3.70 | Amprolium-induced cerebrocortical necrosis (CCN) in dromedary racing camels. ( Haydn-Evans, J; Kinne, J; Wernery, U, 1998) |
| "Culture of neuroblastoma cells in a medium of low-thiamine concentration (6 nM) and in the presence of the transport inhibitor amprolium leads to the appearance of overt signs of necrosis; i." | 3.69 | Thiamine deficiency--induced partial necrosis and mitochondrial uncoupling in neuroblastoma cells are rapidly reversed by addition of thiamine. ( Bettendorff, L; Goessens, G; Grisar, T; Sluse, F; Wins, P, 1995) |
| "For observing biochemical and morphopathological changes in experimental cerebrocortical necrosis, 6 sheep and 6 calves were given amprolium (600 mg/kg/day)." | 3.69 | Biochemical and pathological findings on sheep and calves dying of experimental cerebrocortical necrosis. ( Hirano, K; Horino, R; Itabisashi, T, 1994) |
| "For observing chronological changes of biochemical and pathological aspects in experimental cerebrocortical necrosis, 14 sheep were given amprolium (600 mg/kg/day), and killed at various clinical stages." | 3.69 | Biochemical and pathological observations on sheep showing various clinical manifestations of experimental cerebrocortical necrosis. ( Hirano, K; Horino, R; Itabisashi, T, 1994) |
| "Purposing to get some hints on cause and early diagnosis for cerebrocortical necrosis (CCN), CCN was produced in three healthy calves by the oral administration of amprolium." | 3.67 | Clinical and biochemical findings in bovine cerebrocortical necrosis produced by oral administration of amprolium. ( Ichijo, S; Kasahara, T; Osame, S; Sarashina, T, 1989) |
| "Cerebrocortical necrosis (CCN) was experimentally induced in three calves with the thiamine antagonist Amprolium." | 3.66 | [Ultrastructural study of experimental cerebrocortical necrosis in calves (author's transl)]. ( Askaa, J; Møller, T, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bettendorff, L | 1 |
| Sluse, F | 1 |
| Goessens, G | 1 |
| Wins, P | 1 |
| Grisar, T | 1 |
| Horino, R | 3 |
| Itabisashi, T | 3 |
| Hirano, K | 3 |
| Wernery, U | 1 |
| Haydn-Evans, J | 1 |
| Kinne, J | 1 |
| Askaa, J | 1 |
| Møller, T | 1 |
| Maeda, M | 1 |
| Kasahara, T | 1 |
| Ichijo, S | 1 |
| Osame, S | 1 |
| Sarashina, T | 1 |
| Deutsch, K | 1 |
| Markson, LM | 1 |
| Lewis, G | 1 |
| Terlecki, S | 1 |
| Edwin, EE | 1 |
| Ford, JE | 1 |
9 other studies available for amprolium and Necrosis
| Article | Year |
|---|---|
Thiamine deficiency--induced partial necrosis and mitochondrial uncoupling in neuroblastoma cells are rapidly reversed by addition of thiamine.
Topics: Amprolium; Microscopy, Electron; Mitochondria; Necrosis; Neuroblastoma; Thiamine; Thiamine Deficienc | 1995 |
Biochemical and pathological findings on sheep and calves dying of experimental cerebrocortical necrosis.
Topics: Amprolium; Animals; Brain Diseases; Cattle; Cerebral Cortex; Electroencephalography; Erythrocytes; F | 1994 |
Biochemical and pathological observations on sheep showing various clinical manifestations of experimental cerebrocortical necrosis.
Topics: Amprolium; Animals; Brain; Brain Diseases; Cerebral Cortex; Electroencephalography; Female; Liver; M | 1994 |
Amprolium-induced cerebrocortical necrosis (CCN) in dromedary racing camels.
Topics: Amprolium; Animals; Camelus; Cerebral Cortex; Coccidiostats; Encephalomalacia; Necrosis; Thiamine De | 1998 |
[Ultrastructural study of experimental cerebrocortical necrosis in calves (author's transl)].
Topics: Amprolium; Animals; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Microscopy, Electron; | 1978 |
Electroencephalographic observation on sheep and cattle with experimental cerebrocortical necrosis.
Topics: Amprolium; Animals; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Electrodes, Implanted; | 1990 |
Clinical and biochemical findings in bovine cerebrocortical necrosis produced by oral administration of amprolium.
Topics: Administration, Oral; Amprolium; Animals; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; | 1989 |
An electron microscopical study of the cerebral cortex of the calf. II. The calf with amprolium-induced cerebrocortical necrosis.
Topics: Amprolium; Animals; Antiprotozoal Agents; Axons; Brain Diseases; Cattle; Cattle Diseases; Cell Membr | 1973 |
The aetiology of cerebrocortical necrosis: the effects of administering antimetabolites of thiamine to preruminant calves.
Topics: Amprolium; Animals; Antimetabolites; Blindness; Cattle; Cattle Diseases; Cerebral Cortex; Diarrhea; | 1972 |