amprolium has been researched along with Deficiency, Thiamine in 18 studies
Amprolium: A veterinary coccidiostat that interferes with THIAMINE metabolism.
amprolium : An organic chloride salt having 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium as the counterion. Used for prevention of coccidiosis in poultry and cattle.
amprolium(1+) : A pyridinium ion that is the cationic portion of amprolium, a veterinary drug which is used for prevention of coccidiosis in poultry and cattle.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain." | 7.75 | Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase. ( Fan, Z; Ke, ZJ; Luo, J; Wang, X, 2009) |
| "Recent evidence suggests that alterations in oxidative metabolism induced by thiamine deficiency lead to neuronal cell death." | 7.74 | Thiamine deficiency caused by thiamine antagonists triggers upregulation of apoptosis inducing factor gene expression and leads to caspase 3-mediated apoptosis in neuronally differentiated rat PC-12 cells. ( Chorna, N; Chornyy, S; Parkhomenko, J, 2007) |
| "Amprolium was successfully used to induce cerebrocortical necrosis (CCN) in dromedary racing camels, only when they were fed on a barley diet." | 7.70 | Amprolium-induced cerebrocortical necrosis (CCN) in dromedary racing camels. ( Haydn-Evans, J; Kinne, J; Wernery, U, 1998) |
| "Culture of neuroblastoma cells in a medium of low-thiamine concentration (6 nM) and in the presence of the transport inhibitor amprolium leads to the appearance of overt signs of necrosis; i." | 7.69 | Thiamine deficiency--induced partial necrosis and mitochondrial uncoupling in neuroblastoma cells are rapidly reversed by addition of thiamine. ( Bettendorff, L; Goessens, G; Grisar, T; Sluse, F; Wins, P, 1995) |
| " Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain." | 3.75 | Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase. ( Fan, Z; Ke, ZJ; Luo, J; Wang, X, 2009) |
| "Recent evidence suggests that alterations in oxidative metabolism induced by thiamine deficiency lead to neuronal cell death." | 3.74 | Thiamine deficiency caused by thiamine antagonists triggers upregulation of apoptosis inducing factor gene expression and leads to caspase 3-mediated apoptosis in neuronally differentiated rat PC-12 cells. ( Chorna, N; Chornyy, S; Parkhomenko, J, 2007) |
| " Lesions seen were felt to be familial or due to the effects of an amprolium-induced thiamine deficiency on the developing brains of these puppies." | 3.73 | A degenerative encephalomyelopathy in 7 Kuvasz puppies. ( de Lahunta, A; Hazlett, MJ; Smith-Maxie, LL, 2005) |
| "Amprolium was successfully used to induce cerebrocortical necrosis (CCN) in dromedary racing camels, only when they were fed on a barley diet." | 3.70 | Amprolium-induced cerebrocortical necrosis (CCN) in dromedary racing camels. ( Haydn-Evans, J; Kinne, J; Wernery, U, 1998) |
| "Culture of neuroblastoma cells in a medium of low-thiamine concentration (6 nM) and in the presence of the transport inhibitor amprolium leads to the appearance of overt signs of necrosis; i." | 3.69 | Thiamine deficiency--induced partial necrosis and mitochondrial uncoupling in neuroblastoma cells are rapidly reversed by addition of thiamine. ( Bettendorff, L; Goessens, G; Grisar, T; Sluse, F; Wins, P, 1995) |
| "For observing chronological changes of biochemical and pathological aspects in experimental cerebrocortical necrosis, 14 sheep were given amprolium (600 mg/kg/day), and killed at various clinical stages." | 3.69 | Biochemical and pathological observations on sheep showing various clinical manifestations of experimental cerebrocortical necrosis. ( Hirano, K; Horino, R; Itabisashi, T, 1994) |
| "Cerebrocortical necrosis (CCN) was experimentally induced in three calves with the thiamine antagonist Amprolium." | 3.66 | [Ultrastructural study of experimental cerebrocortical necrosis in calves (author's transl)]. ( Askaa, J; Møller, T, 1978) |
| "Polioencephalomalacia was induced in eight buffalo calves, 6-12 months old, by drenching amprolium (300 mg/kg body weight per day) for 29-55 days." | 1.29 | Polioencephalomalacia induced with amprolium in buffalo calves--clinicopathologic findings. ( Gahlot, AK; Malik, KS; Tanwar, RK, 1994) |
| "Amprolium was undetectable in eggs purchased at several retail outlets." | 1.27 | Thiamin inadequacy in infants: lack of evidence of amprolium in egg yolk. ( Elliott, LE; Kerr, D; Marriott, JM; Massera, FC; Thornber, EJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ke, ZJ | 2 |
| Wang, X | 2 |
| Fan, Z | 2 |
| Luo, J | 2 |
| RINDI, G | 1 |
| FERRARI, G | 1 |
| VENTURA, U | 1 |
| Polin, D | 1 |
| Wynosky, ER | 1 |
| Porter, CC | 1 |
| Hazlett, MJ | 1 |
| Smith-Maxie, LL | 1 |
| de Lahunta, A | 1 |
| Wang, B | 1 |
| Shi, X | 1 |
| Chornyy, S | 1 |
| Parkhomenko, J | 1 |
| Chorna, N | 1 |
| Thornber, EJ | 1 |
| Elliott, LE | 1 |
| Kerr, D | 1 |
| Marriott, JM | 1 |
| Massera, FC | 1 |
| Bettendorff, L | 1 |
| Sluse, F | 1 |
| Goessens, G | 1 |
| Wins, P | 1 |
| Grisar, T | 1 |
| Tanwar, RK | 1 |
| Malik, KS | 1 |
| Gahlot, AK | 1 |
| Horino, R | 1 |
| Itabisashi, T | 1 |
| Hirano, K | 1 |
| Dodd, PR | 1 |
| Thomas, GJ | 1 |
| McCloskey, A | 1 |
| Crane, DI | 1 |
| Smith, ID | 1 |
| Wernery, U | 1 |
| Haydn-Evans, J | 1 |
| Kinne, J | 1 |
| Park, LC | 1 |
| Calingasan, NY | 1 |
| Uchida, K | 1 |
| Zhang, H | 1 |
| Gibson, GE | 1 |
| Cymbaluk, NF | 1 |
| Fretz, PB | 1 |
| Loew, FM | 2 |
| Askaa, J | 1 |
| Møller, T | 1 |
| Schaller, K | 1 |
| Brammertz-Buchen, C | 1 |
| Brammertz, KH | 1 |
| Höller, H | 1 |
| Morgan, KT | 1 |
| Dunlop, RH | 1 |
18 other studies available for amprolium and Deficiency, Thiamine
| Article | Year |
|---|---|
Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase.
Topics: Alcoholism; Amprolium; Animals; Cell Death; Cells, Cultured; Central Nervous System Depressants; Coc | 2009 |
[INFLUENCE OF AMPROLIUM ON THE THIAMINE CONTENT OF RAT TISSUES].
Topics: Amprolium; Metabolism; Pharmacology; Pyridines; Pyrimidines; Rats; Research; Thiamine; Thiamine Defi | 1963 |
Amprolium. V. Studies on thiamine deficiency in laying chickens and their eggs.
Topics: Amprolium; Animals; Chickens; Diet; Eggs; Meat; Nutrition Assessment; Poultry; Thiamine; Thiamine De | 1962 |
A degenerative encephalomyelopathy in 7 Kuvasz puppies.
Topics: Amprolium; Animals; Animals, Newborn; Antiprotozoal Agents; Ataxia; Brain; Central Nervous System Di | 2005 |
Thiamine deficiency induces endoplasmic reticulum stress in neurons.
Topics: Amprolium; Animals; Apoptosis; Biomarkers; Brain; Caspase 12; Caspase Inhibitors; Cells, Cultured; C | 2007 |
Thiamine deficiency caused by thiamine antagonists triggers upregulation of apoptosis inducing factor gene expression and leads to caspase 3-mediated apoptosis in neuronally differentiated rat PC-12 cells.
Topics: Active Transport, Cell Nucleus; Amprolium; Animals; Annexin A5; Apoptosis; Apoptosis Inducing Factor | 2007 |
Thiamin inadequacy in infants: lack of evidence of amprolium in egg yolk.
Topics: Amprolium; Animal Feed; Egg Yolk; Female; Humans; Infant; Picolines; Thiamine Deficiency | 1983 |
Thiamine deficiency--induced partial necrosis and mitochondrial uncoupling in neuroblastoma cells are rapidly reversed by addition of thiamine.
Topics: Amprolium; Microscopy, Electron; Mitochondria; Necrosis; Neuroblastoma; Thiamine; Thiamine Deficienc | 1995 |
Polioencephalomalacia induced with amprolium in buffalo calves--clinicopathologic findings.
Topics: Amprolium; Animals; Buffaloes; Disease Models, Animal; Encephalomalacia; Male; Random Allocation; Th | 1994 |
Biochemical and pathological observations on sheep showing various clinical manifestations of experimental cerebrocortical necrosis.
Topics: Amprolium; Animals; Brain; Brain Diseases; Cerebral Cortex; Electroencephalography; Female; Liver; M | 1994 |
The neurochemical pathology of thiamine deficiency: GABAA and glutamateNMDA receptor binding sites in a goat model.
Topics: Alcoholism; Amprolium; Animals; Brain Chemistry; Diazepam; Disease Models, Animal; Dizocilpine Malea | 1996 |
Amprolium-induced cerebrocortical necrosis (CCN) in dromedary racing camels.
Topics: Amprolium; Animals; Camelus; Cerebral Cortex; Coccidiostats; Encephalomalacia; Necrosis; Thiamine De | 1998 |
Metabolic impairment elicits brain cell type-selective changes in oxidative stress and cell death in culture.
Topics: Aldehydes; Amprolium; Animals; Apoptosis; Brain; Cell Death; Cells, Cultured; Coloring Agents; Ketog | 2000 |
Amprolium-induced thiamine deficiency in horses: clinical features.
Topics: Amprolium; Animals; Ataxia; Blood Glucose; Diarrhea; Horse Diseases; Horses; Lactates; Male; Phospho | 1978 |
[Ultrastructural study of experimental cerebrocortical necrosis in calves (author's transl)].
Topics: Amprolium; Animals; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Microscopy, Electron; | 1978 |
[Biological activity of so-called thiamine antagonists in rats with suboptimal thiamine supply].
Topics: Amprolium; Animals; Antimetabolites; Brain; Caffeic Acids; Erythrocytes; Hemin; Male; Rats; Silage; | 1977 |
Amprolium poisoning of preruminant lambs. An ultrastructural study of the cerebral malacia and the nature of the inflammatory response.
Topics: Amprolium; Animals; Antiprotozoal Agents; Axons; Brain Edema; Cerebral Cortex; Cerebral Hemorrhage; | 1974 |
Induction of thiamine inadequacy and polioencephalomalacia in adult sheep with amprolium.
Topics: Amprolium; Animals; Antiprotozoal Agents; Cardiac Output; Encephalomalacia; Erythrocytes; Female; Hy | 1972 |