amphotericin-b has been researched along with Vitiligo* in 2 studies
2 other study(ies) available for amphotericin-b and Vitiligo
Article | Year |
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[Anogenital condylomata acuminata, mucocutaneous candidiasis, vitiligo, keratopathy and primary hypoparathyroidism in an autoimmune polyglandular syndrome type 1].
6 months before admission a 21-year-old woman had developed anogenital condylomata acuminata (CA). Since early childhood she had been treated for primary hypoparathyroidism (PHPT) and recurrent mucocutaneous candidiasis. 5 years before admission corneal clouding had caused visual impairment. Recently, mainly truncal vitiligo with occipital poliosis had developed.. PHPT was confirmed (parathormone level 7.7 mg/l). In addition, liver transaminases were raised (GOT 105.8 U/l, GPT 145.6 U/l, gamma-GT 56.8 U/l), pointing to noninfectious hepatitis. An ACTH stress test could not exclude manifest adrenocortical insufficiency, and thyroid function was also normal. The Merieux Multitest indicated an anergy.. The constellation of test results suggested autoimmune polyglandular syndrome type I. The condylomata were treated by electrocautery and the intestinal candidiasis with amphotericin B suspension. Calcitriol capsules, 0.5 microgram, and calcium gluconate or lactate, 500 and 300 mg respectively, 3 times daily each, were given for the PHPT.. This case demonstrates a complex syndrome which can be recognized early by simple clinical tests. Early diagnosis prevents possible life-threatening complications. Topics: Adult; Amphotericin B; Antifungal Agents; Anus Diseases; Calcitriol; Calcium Gluconate; Candidiasis, Chronic Mucocutaneous; Capsules; Condylomata Acuminata; Corneal Opacity; Drug Therapy, Combination; Electrocoagulation; Female; Humans; Hypoparathyroidism; Lactates; Polyendocrinopathies, Autoimmune; Scalp; Suspensions; Vaginal Diseases; Vitiligo | 1997 |
Transfer factor as an approach to the treatment of immune deficiency disease.
Use of transfer factor in the treatment of chronic mucocutaneous candidiasis is discussed. The clinical experience in treating 2 patients with different clinical expressions of the syndrome and their different responses to treatment with repeated injections of transfer factor given in conjunction with amphotericin-B are reported. Results indicate that this form of therapy is a safe and effective way of restoring cell-mediated immunity to Candida and successfully treating some patients with chronic mucocutaneous candidiasis. Topics: Amphotericin B; Candida albicans; Candidiasis, Cutaneous; Candidiasis, Oral; Child; Female; Humans; Hypoparathyroidism; Immunity, Cellular; Immunologic Deficiency Syndromes; Lymphocyte Activation; Paronychia; Skin Tests; Thymidine; Transfer Factor; Tritium; Vitiligo | 1975 |