amphotericin-b and Syphilis

Opportunistic infections have been reported infrequently in primary HIV infection. We report a case of cryptococcemia in primary HIV infection. To our knowledge there has not been such a case reported. Our case highlights the need for clinicians to be wary of other opportunistic infections, including cryptococcosis, in primary HIV infection.

Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Diabetes Mellitus; Fluconazole; Hepatitis B; HIV Infections; Humans; Liver Function Tests; Male; Syphilis; Treatment Outcome

A 34-year-old, HIV-positive man living in Texas presented with a 2-week history of fever, malaise, myalgias, oral ulcers, and papules on his chest, back, face, and extremities, including the palms. Initially secondary syphilis was suspected. However, RPR was negative. Histopathologic examination revealed a lymphocytic infiltrate with numerous intra-histiocytic fungal organisms. GMS and PAS stains were positive, consistent with the diagnosis of histoplasmosis. We report a case of disseminated histoplasmosis clinically mimicking secondary syphilis.

Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Biopsy; Cryptococcosis; Diagnosis, Differential; Endemic Diseases; Hepatomegaly; Histoplasmosis; Humans; Itraconazole; Male; Syphilis; Texas

Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine

Topics: Adrenal Cortex Hormones; Amphotericin B; Anti-Bacterial Agents; Antitubercular Agents; Ethionamide; Humans; Isoniazid; Meningitis; Meningitis, Viral; Mycoses; Prognosis; Sarcoidosis; Streptodornase and Streptokinase; Streptomycin; Syphilis; Tuberculosis, Meningeal

Topics: Amphotericin B; Arthritis; Aspergillosis; Bacteriological Techniques; Bronchography; Cortisone; Humans; Iodides; Lung Diseases, Fungal; Pathology; Penicillins; Syphilis; Tomography; Tomography, X-Ray Computed

Topics: Amphotericin B; Animals; Antibodies; Antigens; Coloring Agents; Sheep; Staining and Labeling; Syphilis; Syphilis Serodiagnosis