amphotericin-b and Penile-Diseases

Topics: Amphotericin B; Debridement; Diagnosis, Differential; Dose-Response Relationship, Drug; Humans; Liposomes; Male; Middle Aged; Penile Diseases; Rhizopus; Zygomycosis

Topics: Amphotericin B; Antifungal Agents; Biopsy; Diagnosis, Differential; Fusarium; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung; Male; Middle Aged; Mycoses; Penile Diseases; Respiratory Tract Infections; Spain; Tomography, X-Ray Computed; Ulcer

Topics: Abscess; Amphotericin B; Candidiasis; Combined Modality Therapy; Drug Therapy, Combination; Erectile Dysfunction; Humans; Ketoconazole; Male; Middle Aged; Penile Diseases; Prostheses and Implants

A recurrence of cryptococcosis sixteen years after the primary infection as a penile ulcer is reported. The clinical manifestations of genitourinary and skin involvement by cryptococci are discussed. The epidemiology, pathogenesis, diagnosis, and treatment of penile mycotic infections are reviewed.

Topics: Amphotericin B; Cryptococcosis; Humans; Male; Middle Aged; Penile Diseases; Recurrence

Cellulitis of the scrotum and penis is caused, in the majority of instances, by a beta hemolytic streptococci without a discernible portal of entry. Clostridium, occasionally, will result in this disease as a manifestation of a perirectal abscess. In either instance, fluid accumulates rapidly in the closed space between Colles' and Buck's fascia, producing intense swelling of the scrotum. If this compartment is not immediately decompressed by linear incisions, devascularization of the scrotal and penile skin will often occur, resulting in gangrene. Immediate treatment of the bacterial infection with penicillin also is essential. If gangrene does develop, radical debridement of the necrotic tissue as well as a wide margin of adjacent inflamed skin must be undertaken. Continual monitoring of the microflora of the debrided would is essential for the selection of the appropriate antibiotic against any secondary intruders. Coverage of the granulating would is accomplished when the would bacterial count is below 10-5 per gram of tissue.

Topics: Amphotericin B; Anti-Bacterial Agents; Antistreptolysin; Candida albicans; Candidiasis; Cellulitis; Debridement; Gangrene; Genital Diseases, Male; Humans; Immunity; Male; Middle Aged; Penile Diseases; Scrotum; Skin Diseases; Skin Transplantation; Streptococcal Infections; Transplantation, Autologous

In a retrospective study of 51 cases of systemic North American blastomycosis 11 patients were found to have genitourinary tract involvement, the prostate and epididymis being most commonly affected. Diagnosis was made by culture of the fungus from urine, abscess or prostate secretions, morphologic identification of the characteristic organism in urine or secretions, or histologic examination of tissue specimens. Treatment with amphotericin B reduced the mortality rate of 90 per cent to as low as 10 per cent. Long-term followup is necessary because of a relapse rate of 10 to 15 per cent.

Topics: Adult; Aged; Amphotericin B; Blastomycosis; Epididymitis; Genital Diseases, Male; Humans; Kidney Diseases; Male; Middle Aged; Penile Diseases; Potassium Iodide; Prostatic Diseases; Stilbamidines; Testicular Diseases