amphotericin-b and Paronychia

Topics: Amphotericin B; Candida; Candidiasis; Candidiasis, Cutaneous; Candidiasis, Oral; Candidiasis, Vulvovaginal; Cheilitis; Female; Folliculitis; Gastrointestinal Diseases; Humans; Immunologic Deficiency Syndromes; Intertrigo; Leukoplakia, Oral; Male; Nystatin; Paronychia

Topics: Amphotericin B; Candidiasis, Cutaneous; Humans; Nystatin; Paronychia

Blastomycosis is an unusual fungal infection in children. It is often a chronic infection characterized by granulomatous and suppurative lesions. Clinical manifestations include either pulmonary findings or disseminated disease. Disseminated blastomycosis usually begins with a lung infection that spreads to the skin, bones, and central nervous system. This is a case report of a child with chronic blastomycosis presenting with chronic paronychia, fever, cough, malaise, and back pain. The child underwent surgical drainage of a paravertebral abscess and administration of intravenous amphotericin B. He was discharged in good condition on oral therapy with ketoconazole. The literature on blastomycosis, with particular emphasis on clinical presentations and management, is reviewed. When the history and physical examination suggest a chronic granulomatous or disseminated disease, such as tuberculosis, the physician must include blastomycosis in the differential.

Topics: Abscess; Amphotericin B; Antifungal Agents; Blastomycosis; Child; Chronic Disease; Humans; Ketoconazole; Male; Osteomyelitis; Paronychia; Spinal Diseases

Topics: Adrenal Cortex Hormones; Amphotericin B; Candidiasis; Candidiasis, Cutaneous; Candidiasis, Oral; Female; Fingers; Glossitis; Humans; Infant, Newborn; Lip; Male; Metabolic Diseases; Middle Aged; Nutrition Disorders; Paronychia; Pregnancy; Vulvovaginitis

Use of transfer factor in the treatment of chronic mucocutaneous candidiasis is discussed. The clinical experience in treating 2 patients with different clinical expressions of the syndrome and their different responses to treatment with repeated injections of transfer factor given in conjunction with amphotericin-B are reported. Results indicate that this form of therapy is a safe and effective way of restoring cell-mediated immunity to Candida and successfully treating some patients with chronic mucocutaneous candidiasis.

Topics: Amphotericin B; Candida albicans; Candidiasis, Cutaneous; Candidiasis, Oral; Child; Female; Humans; Hypoparathyroidism; Immunity, Cellular; Immunologic Deficiency Syndromes; Lymphocyte Activation; Paronychia; Skin Tests; Thymidine; Transfer Factor; Tritium; Vitiligo

Topics: Amphotericin B; Antifungal Agents; Balanitis; Candida albicans; Candidiasis, Cutaneous; Candidiasis, Oral; Candidiasis, Vulvovaginal; Coloring Agents; Contraceptives, Oral; Diabetes Complications; Female; Humans; Infant, Newborn; Male; Nails; Nystatin; Paronychia; Pregnancy; Pregnancy Complications, Infectious; Saccharomyces

Topics: Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Candidiasis, Oral; Diaper Rash; Drug Resistance, Microbial; Female; Griseofulvin; Humans; Male; Mouth Diseases; Nystatin; Ointments; Paronychia; Pruritus Ani; Skin Diseases; Tinea; Tinea Pedis; Tinea Versicolor

Topics: Amphotericin B; Candidiasis; Child, Preschool; Female; Fungal Vaccines; Granuloma; Humans; Paronychia; Phagocytosis; Scalp Dermatoses