amphotericin-b and Otitis-Media

This is the second case report of a temporal bone osteomyelitis caused by Blastomyces dermatitidis, which presented as a chronic serous otitis media. The presenting serous otitis media was refractory to conventional medical and surgical management and progressed to a temporal bone osteomyelitis prior to diagnosis. B. dermatitidis is a rare fungal pathogen that causes a systemic pyogranulomatous disease that primarily manifests itself in the skin, bones, pulmonary, and genitourinary systems. If left untreated it is associated with a high rate of mortality. The otologic presentation of this rare disease is emphasized, while the clinical and therapeutic features are reviewed.

Topics: Adult; Amphotericin B; Blastomyces; Blastomycosis; Central Nervous System; Ear, Middle; Female; Granuloma; Hearing Loss, Conductive; Humans; Ketoconazole; Magnetic Resonance Imaging; Osteomyelitis; Otitis Media; Temporal Bone; X-Rays

Topics: Amphotericin B; Ampicillin; Anti-Bacterial Agents; Aspirin; Cephalexin; Drug Prescriptions; Erythromycin; Haemophilus influenzae; Humans; Metronidazole; Nystatin; Otitis Media; Penicillins; Pharyngitis; Staphylococcus; Streptococcus pyogenes

Topics: Adult; Amphotericin B; Biopsy; Blastomycosis; Diagnosis, Differential; Ear, Middle; Female; Humans; Otitis Media

Topics: Adult; Amphotericin B; Eye Manifestations; Eyelids; Humans; Injections, Intravenous; Male; Mastoiditis; Middle Aged; Mucor; Mucormycosis; Otitis Media; Rhinitis; Skin Manifestations

Topics: Adenoidectomy; Amphotericin B; Anemia; Anti-Bacterial Agents; Ear, Inner; Hemorrhage; Hydrocarbons; Meningitis; Mycoses; Nystatin; Otitis Media; Otolaryngology; Pediatrics; Pharynx; Streptomycin; Tonsillectomy; Toxicology; Vitamins