amphotericin-b and Lymphoma--T-Cell

Topics: Adalimumab; Adult; Amphotericin B; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antiprotozoal Agents; Brazil; Diagnosis, Differential; Granuloma; Humans; Infliximab; Leishmaniasis, Mucocutaneous; Lymphoma, T-Cell; Male; Tumor Necrosis Factor-alpha

Non-Hodgkin's lymphoma (NHL) is predominantly a disease of lymph nodes, but extranodal involvement is not very uncommon. Palatal involvement by NHL is rare. Mucormycosis is a devastating fungal infection commonly seen in immunocompromised individuals, including those with NHL, but it is affecting the same region has been reported very rarely. Simultaneous infiltration of hard palate by NHL and mucormycosis is extremely unusual. Herein we describe a patient who presented with palatal hole with histopathological examination revealing presence of lymphoma with colesional mucormycosis. The identification of mucor was vital because chemotherapy alone in the absence of antifungals would have had devastating consequences as the mortality of untreated mucormycosis is high.

Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Debridement; Doxorubicin; Humans; Lymphoma, T-Cell; Male; Middle Aged; Mucormycosis; Nasal Cavity; Opportunistic Infections; Palatal Neoplasms; Palate, Hard; Prednisolone; Rhinitis; Vincristine

Topics: Amphotericin B; Antifungal Agents; Antineoplastic Agents; Drug Administration Schedule; Echinocandins; Fatal Outcome; Female; Humans; Lipopeptides; Liposomes; Lymphoma, T-Cell; Maxillary Sinus Neoplasms; Micafungin; Middle Aged; Nasal Cavity; Nose Neoplasms; Pulmonary Aspergillosis