amphotericin-b and Lymphoma--AIDS-Related

Rhodotorula is a ubiquitous yeast that can infect immunocompromised patients. Here, we present the case of a 45-year-old patient with AIDS who developed a Rhodotorula mucilaginosa fungemia. The patient had a past history of visceral leishmaniasis (VL) and was hospitalised to receive chemotherapy for a B-cell lymphoma of the sinonasal cavities. The patient had no fever and no signs of VL. A systematic research for Leishmania by blood and bone marrow cultures was made and he received liposomal amphtotericin B (3 mg/kg in a single dose) to prevent a VL relapse. Rhodotorula fungemia was accidentally detected after 17 days of blood culture using a specific medium for leishmaniasis diagnosis. This long culture incubation time was probably facilitated by amphotericin B treatment. Rhodotorula is an emerging pathogen that may escape detection due its slow growth in culture.

Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Culture Media; Fungemia; Humans; Leishmaniasis, Visceral; Lymphoma, AIDS-Related; Male; Middle Aged; Rhodotorula

We report here a case of localized oral Fusarium infection in an AIDS patient who developed an ulceration in the soft palate. Fusarium solani was identified by histopathology and culture. We believe this to be the second reported case of oral Fusarium infection in a patient with haematological malignancy and the first reported association of oral Fusarium infection with AIDS.

Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Female; Fusarium; Humans; Lymphoma, AIDS-Related; Mycoses

Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Infective Agents; Humans; Infections; Lymphoma, AIDS-Related; Male; Neutropenia; Prototheca; Skin Diseases, Infectious