amphotericin-b and Leukemoid-Reaction

The data are available on 23 cases of eosinophil-type leukemoid reaction to infection with Paecilomyces fungi treated in 1980-1987. The clinical course presented with high fever on the onset followed by the subfebrile temperature later, symptoms of upper respiratory tract catarrh, enlargement of peripheral lymph nodes, involvement of other organs, 78-84% eosinophilia, leukocytosis at the onset. Upon establishment of accurate diagnosis by specific laboratory tests, the etiopathogenetic treatment was administered. The response was achieved in 94% of the patients.

Topics: Adolescent; Adult; Amphotericin B; Animals; Chronic Disease; Eosinophilia; Female; Fever; Guinea Pigs; Humans; Leukemoid Reaction; Male; Mice; Middle Aged; Mycoses; Paecilomyces