amphotericin-b and Ileal-Diseases

Topics: Abdominal Pain; Acquired Immunodeficiency Syndrome; Adult; Amphotericin B; Anti-HIV Agents; Histoplasma; Histoplasmosis; Humans; Ileal Diseases; Ileocecal Valve; Infusions, Intravenous; Intestinal Fistula; Itraconazole; Male; Opportunistic Infections; Rare Diseases; Risk Assessment; Treatment Outcome

Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Arthritis, Rheumatoid; Colitis, Ulcerative; Combined Modality Therapy; Drainage; Fatal Outcome; Gastrointestinal Diseases; Humans; Ileal Diseases; Intestinal Perforation; Intraoperative Complications; Jejunal Diseases; Liposomes; Male; Mucormycosis; Peritonitis; Postoperative Complications; Shock, Septic; Triazoles

Topics: Amphotericin B; Antifungal Agents; Diagnosis, Differential; Digestive System Surgical Procedures; Enterocolitis, Necrotizing; Gastrointestinal Diseases; Humans; Ileal Diseases; Infant, Newborn; Laparotomy; Male; Mucormycosis; Treatment Outcome

Gastrointestinal mucormycosis is an uncommon opportunistic fungal infection often presents in immunocompromised patients. Direct invasion of the intestinal walls by spores from ingested food is the main pathogenetic mechanism of this disease, which usually takes place in stomach and colon. Early diagnosis is critical, especially in vascular invasive types, due to its high mortality rate close to 100%. In the past when appropriate diagnostic tools were not available, mucormycosis were frequently found with autopsy. The advance in current endoscopic technology has increased diagnostic rate and made successful management available with appropriate treatments such as debridement of contaminated tissues. In this case report, we discussed a case of ileal mucormycosis diagnosed by colonoscopy and treated with anti-fungal agent successfully.

Topics: Amphotericin B; Antifungal Agents; Colonoscopy; Humans; Ileal Diseases; Ileum; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Mucormycosis; Tomography, X-Ray Computed; Young Adult

A renal transplant patient presented with ileal perforation due to histoplasmosis 3 years after transplantation. Mesenteric lymph nodes and lungs were also affected by the disease. She was successfully treated with amphotericin B followed by ketoconazole.

Topics: Adult; Amphotericin B; Diagnosis, Differential; Female; Histoplasmosis; Humans; Ileal Diseases; Intestinal Perforation; Ketoconazole; Kidney Transplantation

Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Appendix; Aspergillosis; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Ileal Diseases; Iliac Vein; Intestinal Perforation; Ischemia; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neutropenia; Thrombosis