amphotericin-b and Epididymitis

Topics: Amphotericin B; Antifungal Agents; Candidiasis; Epididymitis; Humans; Hydronephrosis; Infant; Kidney; Kidney Diseases; Male; Risk Factors; Treatment Outcome; Ultrasonography

A rare case of coccidioidomycosis involving the epididymis is described and compared with the 12 clinically diagnosed cases reported in the literature. With 1 exception, the disease appeared to be limited to the genital organs and the adjacent tissue. Surgical excision of the involved tissue appeared to be curative. Bilateral epididymal involvement occurred in 4 cases and it was the cause of the treatment failure in 2 of the 3 cases in which the local disease was treated unsuccessfully by surgery. The efficacy of antifungal chemotherapy remains to be determined.

Topics: Amphotericin B; Coccidioidomycosis; Epididymitis; Humans; Male; Middle Aged

In a retrospective study of 51 cases of systemic North American blastomycosis 11 patients were found to have genitourinary tract involvement, the prostate and epididymis being most commonly affected. Diagnosis was made by culture of the fungus from urine, abscess or prostate secretions, morphologic identification of the characteristic organism in urine or secretions, or histologic examination of tissue specimens. Treatment with amphotericin B reduced the mortality rate of 90 per cent to as low as 10 per cent. Long-term followup is necessary because of a relapse rate of 10 to 15 per cent.

Topics: Adult; Aged; Amphotericin B; Blastomycosis; Epididymitis; Genital Diseases, Male; Humans; Kidney Diseases; Male; Middle Aged; Penile Diseases; Potassium Iodide; Prostatic Diseases; Stilbamidines; Testicular Diseases

Topics: Aged; Amphotericin B; Blood Urea Nitrogen; Coccidioidomycosis; Complement Fixation Tests; Epididymitis; Heart Diseases; Humans; Hypocalcemia; Immunity; Kidney; Male; Potassium; Potassium Chloride; Skin Diseases

Topics: Adult; Amphotericin B; Coccidioidomycosis; Epididymitis; Humans; Male; Prostatitis