amphotericin-b and Enteritis

Protothecosis is an emerging opportunistic infection caused by species belonging to the genus Prototheca. Two Japanese cases of protothecosis are documented with a critical review of the literature. A current perspective concerning the microbiology and disease entity of protothecosis is described in detail.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Arm; Child, Preschool; Dermatomycoses; Enteritis; Female; Humans; Intestinal Mucosa; Japan; Ketoconazole; Lymph Nodes; Male; Middle Aged; Prototheca

Fungal infections of the gastrointestinal tract have risen to higher levels of prevalence in the past decade. Major factors accounting for this increase are social changes, such as the increased ease and frequency of travel, which exposes the individual to environmental conditions that may result in fungal infection; increasing use of antibiotic and hormonal medications by otherwise healthy persons; and improved therapy for other diseases, such as polychemotherapy of cancer with its immunosuppressive effects. Both noninvasive and invasive fungal disease of the intestinal tract in otherwise healthy individuals can be successfully treated. The invasive fungal infections in patients with severe prior underlying disease are often first diagnosed postmortem, but improvement in serologic techniques now offers a possibility of earlier diagnosis and therapeutic intervention.

Topics: Amphotericin B; Antifungal Agents; Candidiasis; Diarrhea; Enteritis; Histoplasmosis; Humans; Imidazoles; Immunosuppression Therapy; Ketoconazole; Miconazole; Mycoses; Neoplasms; Nystatin; Paracoccidioidomycosis; Piperazines; Sulfadiazine

Three premature infants (<800 g) showed invasive Candida at the site of their intestinal perforations. This entity is distinct from Candida peritonitis complicating necrotizing enterocolitis and was uniformly fatal. Recognition and aggressive antifungal therapy may improve outcomes.

Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Enteritis; Fatal Outcome; Female; Humans; Infant, Newborn; Infant, Premature; Intestinal Perforation; Male

Topics: Administration, Oral; Amphotericin B; Antifungal Agents; Colitis, Ulcerative; Creatinine; Enteritis; Humans; Kidney Function Tests; Proteinuria

Topics: Abscess; Amphotericin B; Brain Abscess; Candidiasis; Carrier State; Child; Chloramphenicol; Colistin; Deoxyribonucleases; DNA; Empyema; Enteritis; Humans; Kanamycin; Meningitis; Methicillin; Penicillins; Peritonitis; Phlebitis; Pneumonia; Pneumothorax; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Sulfadiazine; Troleandomycin