amphotericin-b and Back-Pain

Topics: Amphotericin B; Antifungal Agents; Back Pain; Coccidioidomycosis; Diagnosis, Differential; Female; Follow-Up Studies; Fungemia; Humans; Itraconazole; Magnetic Resonance Imaging; Middle Aged; Osteomyelitis; Physical Examination; Severity of Illness Index; Spinal Diseases; Thoracic Vertebrae; Treatment Outcome

We present a case of a 32 year old female with a past medical history of hypertension who presented with several years of chronic back pain and was ultimately diagnosed with isolated pelvic coccidioidomycosis. She was initially seen by gynecologic oncology for assessment of possible metastatic cancer by image study, but a cytopathologic diagnosis of coccidioidomycosis lead to a cancellation of the planned surgery and extensive antifungal treatment managed by the infectious disease team. She had no known previous pulmonary disease or immunodeficiency. Pelvic coccidioidomycosis without known pulmonary disease is very rare, and disseminated infection typically only occurs in those who are severely immunocompromised. Our case presented with several years of back pain and a pelvic mass mistaken for possible malignancy by image study.

Topics: Adult; Amphotericin B; Antifungal Agents; Back Pain; Coccidioidomycosis; Female; Humans; Male; Pelvic Infection; Tomography, X-Ray Computed

Topics: Amphotericin B; Antifungal Agents; Back Pain; Biopsy; Braces; Coccidioidomycosis; Combined Modality Therapy; Diagnosis, Differential; Disease Progression; Fluconazole; Humans; Magnetic Resonance Imaging; Male; Patient Isolation; Spinal Fusion; Spondylitis; Thoracic Vertebrae; Treatment Outcome

Topics: Amphotericin B; Antiprotozoal Agents; Back Pain; Fever; Humans; India; Leishmaniasis, Visceral; Treatment Outcome; Vomiting

A single case of back pain due to Blastomyces dermatitidis infection limited solely to the skeleton is reported with a discussion of the differential diagnosis. This rare disease must be differentiated from other destructive bone lesions such as tuberculosis or tumors because of the availability of effective treatment.

Topics: Amphotericin B; Back Pain; Blastomycosis; Diagnosis, Differential; Female; Humans; Lung; Middle Aged; Osteomyelitis; Spinal Diseases; Spine; Tomography, X-Ray Computed