amphotericin-b has been researched along with Astrocytoma* in 5 studies
5 other study(ies) available for amphotericin-b and Astrocytoma
Article | Year |
---|---|
Penetration of teniposide (VM-26) into human intracerebral tumors. Preliminary observations on the effect of tumor type, rate of drug infusion and prior treatment with amphotericin B or oral glycerol.
Thirty-four consenting patients received VM-26 50-100 mg/m2 I.V. before surgical resection of intracerebral tumor, and drug was measured using a high pressure liquid chromatographic technique. Sufficient tumor for analysis was obtained from 29 patients. Brain metastases (13 patients) had higher concentrations of VM-26 than did gliomas (13 patients). Concentrations were comparable in brain metastases and meningiomas (3 patients). Prolonged (24 h) infusion of VM-26 did not appear to result in higher tumor drug concentrations in 5 patients than did rapid (1 h) infusion in 24 patients. Pretreatment with Amphotericin-B 10 mg/m2 12 h and 1 h before VM-26 did not appear to have any effect on VM-26 uptake into 4 intracerebral tumors, although data were limited, and VM-26 concentrations were very high in 1 metastasis. Pretreatment with oral glycerol 500 mg/kg 18 h, 12 h, 6 h, and immediately before I.V. VM-26 may have resulted in increased penetration of VM-26 into 9 tumors, although confirmation is required. Amphotericin-B, glycerol, and operative conditions did not appear to alter VM-26 plasma pharmacokinetics. Topics: Amphotericin B; Astrocytoma; Brain Neoplasms; Glycerol; Humans; Kinetics; Meningioma; Podophyllotoxin; Teniposide | 1984 |
Letter: Amphotericin B in astrocytoma.
Topics: Adolescent; Adult; Aged; Amphotericin B; Astrocytoma; Brain Neoplasms; Female; Humans; Male; Middle Aged | 1973 |
Remission of astrocytoma following amphotericin-B treatment.
Topics: Amphotericin B; Astrocytoma; Brain Neoplasms; Brain Stem; Candidiasis; Child; Female; Humans; Spinal Cord Neoplasms | 1970 |
Remission of grade 3 astrocytoma after irradiation and amphotericin B.
Topics: Amphotericin B; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Female; Humans | 1970 |
Remission of grade 3 astrocytoma after irradiation and amphotericin B.
Topics: Amphotericin B; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Female; Humans | 1970 |