amphotericin-b and Airway-Obstruction

Penicilliosis is an opportunistic infection in HIV-infected and other immunocompromised patients mostly in Southeast Asia, Southern China, Hong Kong, and Taiwan, with respiratory manifestations in about one-third of patients. We report the case of a 26-year-old non-HIV immunocompromised patient presenting with an airway obstruction caused by penicilliosis, together with a review of the literature of this rare condition.

Topics: Adult; Airway Obstruction; Amphotericin B; Bronchoscopy; Humans; Immunocompromised Host; Itraconazole; Lung Diseases, Fungal; Lupus Erythematosus, Systemic; Male; Mycobacterium Infections, Nontuberculous; Opportunistic Infections; Penicillium

Topics: Airway Obstruction; Amphotericin B; Antifungal Agents; Bronchoscopy; C-Reactive Protein; Eosinophilia; Humans; Itraconazole; Lung Diseases, Fungal; Male; Middle Aged; Mycoses; Penicillium; Treatment Outcome

Topics: Airway Obstruction; Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Bronchoscopy; Fatal Outcome; Female; Humans; Middle Aged; Respiration, Artificial; Tracheal Diseases

Topics: Adult; AIDS-Related Opportunistic Infections; Airway Obstruction; Amphotericin B; Biopsy; Combined Modality Therapy; Female; Fluconazole; Humans; Mycoses; Penicillium; Retropharyngeal Abscess; Tracheostomy

Mucormycosis (phycomycosis) has been reported to involve most organ systems in man. We report a young insulin-dependent diabetic who presented with acute upper airway obstruction because of isolated mucormycosis of the trachea. A combination of amphotericin B and surgical resection of the lower two thirds of the larynx and five tracheal rings with primary reanastomosis has resulted in a cure with no evidence of recurrence after nine months of follow-up. To our knowledge, this represents the first report of isolated tracheal mucormycosis and/or acute upper airway obstruction due to mucormycosis.

Topics: Adult; Airway Obstruction; Amphotericin B; Diabetes Complications; Female; Humans; Mucormycosis; Tracheal Diseases; Tracheotomy

The inpatient experience regarding coccidioidomycosis of head and neck was reviewed at the University of California Medical Center, San Francisco and affiliated hospitals. Four cases in which upper airway obstruction required otolaryngological consultation and intervention are reviewed in detail. History, epidemiology and pathophysiology of coccidioidomycosis involving upper airway are discussed. Suggestions for diagnosis and management are outlined.

Topics: Aged; Airway Obstruction; Amphotericin B; Coccidioidomycosis; Female; Humans; Male; Miconazole; Middle Aged; Radiography; Sex Factors; South America; United States

When clinically apparent, coccidioidomycosis usually presents either as an interstitial pulmonary infiltrate or, later in its course, a parenchymal nodule often with cavitation. The present report concerns a young adult woman whose presentation was one of shortness of breath with wheezing and stridor, secondary to a localized endobronchial coccidiodal granuloma producing nearly complete obstruction of the right mainstem bronchus. Such a presentation has not been reported previously in an adult. The possible association of serious fungal disease with previous jejunoileal bypass surgery is discussed.

Topics: Adult; Airway Obstruction; Amphotericin B; Biopsy; Bronchial Diseases; Bronchoscopy; Coccidioidomycosis; Female; Humans; Tomography, X-Ray

Topics: Airway Obstruction; Amphotericin B; Child, Preschool; Esophageal Diseases; Fungi; Humans; Laryngeal Diseases; Male; Mycoses; Orbit; Respiratory Insufficiency; Tracheal Diseases; Zygoma