amphetamine has been researched along with Substance Withdrawal Syndrome in 220 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Withdrawal from amphetamine is associated with increased anxiety and sensitivity to stressors which are thought to contribute to relapse." | 7.80 | Serotonin in the ventral hippocampus modulates anxiety-like behavior during amphetamine withdrawal. ( Cook, A; Forster, GL; Mears, M; Renner, KJ; Scholl, JL; Tu, W; Watt, MJ, 2014) |
| "Chronic amphetamine use results in anxiety-like states after drug cessation." | 7.79 | The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats. ( Gibula-Bruzda, E; Koltunowska, D; Kotlinska, JH, 2013) |
| "Withdrawal from psychostimulants increases anxiety states, and amphetamine-treated rats show increased CRF(2) receptors in the serotonergic cell body region, the dorsal raphe nucleus (dRN)." | 7.76 | Increased anxiety-like behavior of rats during amphetamine withdrawal is reversed by CRF2 receptor antagonism. ( Forster, GL; Oliver, HA; Oliver, KM; Scholl, JL; Vuong, SM, 2010) |
| "Acute amphetamine administration activates monoaminergic pathways and increases systemic corticosterone, both of which influence anxiety states and adult dentate gyrus neurogenesis." | 7.76 | Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus. ( Barr, JL; Forster, GL; Renner, KJ, 2010) |
| "Trials of novel compounds for the treatment of schizophrenia are typically tested in patients following brief withdrawal of ongoing medication despite known long-term changes in the dopamine (DA) system following chronic antipsychotic drug therapy." | 5.40 | Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia. ( Cook, JM; Gill, KM; Grace, AA; Poe, MM, 2014) |
| "Amphetamine pretreatment induced behavioral sensitization in both rat strains similarly." | 5.35 | The amphetamine sensitization model of schizophrenia: relevance beyond psychotic symptoms? ( Feldon, J; Hauser, J; Peleg-Raibstein, D; Yee, BK, 2009) |
| "Abrupt discontinuation of chronic amphetamine consumption leads to withdrawal symptoms including depression, anhedonia, dysphoria, fatigue, and anxiety." | 3.88 | Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal. ( Afshari, K; Amini-Khoei, H; Amiri, S; Dehpour, AR; Ghesmati, M; Haj-Mirzaian, A; Hashemiaghdam, A; Ramezanzadeh, K, 2018) |
| "Withdrawal from amphetamine is associated with increased anxiety and sensitivity to stressors which are thought to contribute to relapse." | 3.80 | Serotonin in the ventral hippocampus modulates anxiety-like behavior during amphetamine withdrawal. ( Cook, A; Forster, GL; Mears, M; Renner, KJ; Scholl, JL; Tu, W; Watt, MJ, 2014) |
| "Chronic amphetamine use results in anxiety-like states after drug cessation." | 3.79 | The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats. ( Gibula-Bruzda, E; Koltunowska, D; Kotlinska, JH, 2013) |
| "Withdrawal from psychostimulants increases anxiety states, and amphetamine-treated rats show increased CRF(2) receptors in the serotonergic cell body region, the dorsal raphe nucleus (dRN)." | 3.76 | Increased anxiety-like behavior of rats during amphetamine withdrawal is reversed by CRF2 receptor antagonism. ( Forster, GL; Oliver, HA; Oliver, KM; Scholl, JL; Vuong, SM, 2010) |
| "Acute amphetamine administration activates monoaminergic pathways and increases systemic corticosterone, both of which influence anxiety states and adult dentate gyrus neurogenesis." | 3.76 | Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus. ( Barr, JL; Forster, GL; Renner, KJ, 2010) |
| "Administration of amphetamine (AMPH) can induce symptoms of psychosis in humans and locomotor sensitization in rats; in contrast, withdrawal from a period of AMPH intake is most often associated with symptoms of human endogenous depression." | 3.72 | Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests. ( Feldon, J; Murphy, CA; Nanz-Bahr, NI; Pezze, MA; Pryce, CR; Russig, H, 2003) |
| "Amphetamine withdrawal and major depression share many behavioral commonalities in humans." | 3.72 | Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents. ( Cryan, JF; Hoyer, D; Markou, A, 2003) |
| "The symptom of "diminished interest or pleasure" in rewarding stimuli is an affective symptom of nicotine and amphetamine withdrawal, and a core symptom of depression." | 3.71 | Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats. ( Harrison, AA; Liem, YT; Markou, A, 2001) |
| "The study of the effects of repeated amphetamine administration and withdrawal on brain reward function has relevance to both amphetamine dependence and non-drug-induced depressions." | 3.70 | Effects of repeated withdrawal from continuous amphetamine administration on brain reward function in rats. ( Markou, A; Myers, C; Paterson, NE, 2000) |
| " This study evaluated the safety of and pharmacologic interactions between 7 days of transdermal selegiline dosed with patches (Selegiline Transdermal System, STS) that deliver 6 mg/24 hours and 2." | 2.74 | A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion. ( Everhart, T; Harris, DS; Jacob, P; Jones, RT; Lin, E; Mendelson, JE, 2009) |
| "Naturalistic studies of amphetamine withdrawal symptoms and course are also crucial for the development of study designs appropriate for further treatment studies of amphetamine withdrawal." | 2.41 | Treatment for amphetamine withdrawal. ( Jarusuraisin, N; Kittirattanapaiboon, P; Srisurapanont, M, 2001) |
| " Although chronic administration of a drug is usually required to produce tolerance and dependence, even a single dose can result in these effects under certain conditions." | 2.37 | Contributions of neuropharmacology to understanding mechanisms of tolerance and dependence. ( Adler, MW; Geller, EB, 1984) |
| "Amphetamine (AMPH) abuse is a world concern and a serious public health problem." | 1.43 | m-Trifluoromethyl-diphenyldiselenide as a pharmacological tool to treat preference symptoms related to AMPH-induced dependence in rats. ( Barcelos, RCS; Brüning, CA; Burger, ME; Martini, F; Nogueira, CW; Segat, HJ, 2016) |
| "Trials of novel compounds for the treatment of schizophrenia are typically tested in patients following brief withdrawal of ongoing medication despite known long-term changes in the dopamine (DA) system following chronic antipsychotic drug therapy." | 1.40 | Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia. ( Cook, JM; Gill, KM; Grace, AA; Poe, MM, 2014) |
| " These rodent experiments involved chronic administration of 7." | 1.40 | Withdrawal effect of chronic amphetamine exposure during adolescence on complex maze performance. ( Burleson, PW; Cooper, AM; Jacquemin, SJ; Krall, DM; Lim, SL; Rhoades, DJ; Spears, FM; Willmore, CB; Willmore, DC, 2014) |
| "Amphetamine has a significant potential for abuse and addiction." | 1.39 | Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain. ( Andreazza, AC; Che, Y; Cui, YH; Tan, H; Wang, JF; Young, LT, 2013) |
| "Idazoxan treatment facilitated recovery from spontaneous nicotine, but not amphetamine, withdrawal by attenuating reward deficits and increase the number of somatic signs." | 1.36 | The alpha2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in rats. ( Markou, A; Semenova, S, 2010) |
| "Amphetamine pretreatment induced behavioral sensitization in both rat strains similarly." | 1.35 | The amphetamine sensitization model of schizophrenia: relevance beyond psychotic symptoms? ( Feldon, J; Hauser, J; Peleg-Raibstein, D; Yee, BK, 2009) |
| "Amphetamine pre-treatment as well as the conditioning procedure itself potentiated an increase in dopamine levels during formation, but not expression of a conditioned fear response." | 1.35 | Effects of withdrawal from an escalating dose of amphetamine on conditioned fear and dopamine response in the medial prefrontal cortex. ( Feldon, J; Peleg-Raibstein, D, 2008) |
| " If these findings can be shown to extend to mammals, beta-lactam antibiotics might represent a novel pharmacotherapy or adjunct approach for treating drug abuse or serve as a template for drug discovery efforts aimed at treating drug abuse, recovery from drug abuse, or ameliorating the withdrawal from chronic use of therapeutic medications." | 1.35 | The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians. ( Capasso, A; Cavallo, F; Ding, Z; Raffa, RB; Rawls, SM, 2008) |
| "Rats were trained in a sustained attention task and then treated with saline or in accordance with an escalating dosing regimen of AMPH (1-10 mg/kg)." | 1.33 | Sensitized attentional performance and Fos-immunoreactive cholinergic neurons in the basal forebrain of amphetamine-pretreated rats. ( Martinez, V; Parikh, V; Sarter, M, 2005) |
| "Animals were treated with continuous AMPH release (via osmotic mini-pumps at a dosage of 10 mg kg(-1) day(-1) for 7 days) and tested for their performance in L and PPI during withdrawal in a drug free state." | 1.33 | Withdrawal from continuous amphetamine administration abolishes latent inhibition but leaves prepulse inhibition intact. ( Feldon, J; Peleg-Raibstein, D; Russig, H; Sydekum, E, 2006) |
| " After 1-d or 14-d withdrawal from Amph, they were challenged on day 8 (W1d) or on day 21 (W14d) with a single same dosage and then perfused." | 1.32 | Age- and region-dependent alterations in the GABAergic innervation in the brain of rats treated with amphetamine. ( Chen, CT; Lin, TY; Yin, HS, 2004) |
| "The aim of this study was the assessment of disorders after chronic intake of psychoactive drugs, like marijuana, amphetamine, ecstasy, cocaine and opiates." | 1.32 | [Assessment of disorders after chronic psychoactive drug abuse in patients hospitalized in detoxification units]. ( Chrostek Maj, J; Kamenczak, A; Kroch, S; Polewka, A; Szerszeń-Motyka, J, 2004) |
| "0 mg/kg AMPH produced parallel dose-response curve shifts to the right." | 1.32 | Evidence for bidirectional cues as a function of time following treatment with amphetamine: implications for understanding tolerance and withdrawal. ( Barrett, RJ; Caul, WF; Smith, RL, 2004) |
| "In amphetamine-treated rats, a higher proportion of cortical cells fired in bursts, and a larger proportion of accumbens and prefrontal cortical neurons exhibited bistable membrane oscillations." | 1.31 | Amphetamine withdrawal alters bistable states and cellular coupling in rat prefrontal cortex and nucleus accumbens neurons recorded in vivo. ( Grace, AA; Onn, SP, 2000) |
| "After taking bupropion, his withdrawal symptoms i." | 1.31 | Bupropion for amphetamine withdrawal syndrome. ( Boonyanaruthee, V; Chan-Ob, T; Kuntawongse, N, 2001) |
| " Nevertheless, the effects of long-term administration and withdrawal from other drugs, such as fluoxetine, that have the potential to elevate mood in depressed individuals have not been characterized." | 1.30 | Differential effects of withdrawal from chronic amphetamine or fluoxetine administration on brain stimulation reward in the rat--interactions between the two drugs. ( Koob, GF; Lin, D; Markou, A, 1999) |
| "Amphetamine was demonstrated in seven subjects." | 1.30 | Urinary excretion of amphetamine after termination of drug abuse. ( Mørland, J; Skuterud, B; Smith-Kielland, A, 1997) |
| "Amphetamine was given twice daily 5 days per week for 6 weeks at dosages escalating from 1 to 10 mg/kg per injection." | 1.29 | Withdrawal from chronic amphetamine elevates baseline intracranial self-stimulation thresholds. ( Munn, E; Wise, RA, 1995) |
| "Spontaneous locomotor activity and catalepsy were assessed in rats during withdrawal from a schedule of intravenous self-administration of high doses of amphetamine." | 1.29 | Lisuride reduces psychomotor retardation during withdrawal from chronic intravenous amphetamine self-administration in rats. ( Koob, GF; Pulvirenti, L, 1993) |
| "The avoidance of withdrawal symptoms does not motivate further self-administration." | 1.27 | (+)-Amphetamine oral 'drug taking behavior' in naive and tolerant rats. ( Coper, H; Jänicke, UA, 1984) |
| "Rats with ablated frontal sensorimotor cortex and one with ablated sensorimotor connections to forebrain showed more vacuous chewing movements following 6-week chronic administration of a neuroleptic than did occipitally damaged rats or normal controls who were treated in the same way." | 1.26 | Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia. ( Glassman, HN; Glassman, RB, 1980) |
| "Thrombocytosis was not related to withdrawal symptoms or treatment (phenobarbital or paregoric)." | 1.26 | Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users. ( Burstein, Y; Giardina, PJ; Kandall, SR; Peterson, CM; Rausen, AR; Siljestrom, K, 1979) |
| "Pretreatment with haloperidol (0." | 1.25 | Narcotic withdrawal like mouse jumping produced by amphetamine and L-DOPA. ( Colpaert, FC; Laduron, P; Lal, H, 1975) |
| "Mice were given several atropine injections at a high dosage level." | 1.25 | Sensitivity changes to morphine and other drugs induced by cholinergic blockade. ( Contreras, E; Quijada, L; Tamayo, L, 1975) |
| "6 Animals withdrawn following chronic administration of a number of drugs, barbitone, barbitone/bemegride mixture, Mandrax (methaqualone: diphenhydramine; 10: 1), chlordiazepoxide, nitrazepam, chlorpromazine or ethanol, exhibited a significant tolerance to intracerebroventricularly administered pentobarbitone." | 1.25 | A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs. ( Stevenson, IH; Turnbull, MJ, 1974) |
| "After chronic administration of ethanol to mice by the intragastric route head twitches occur as part of the ethanol withdrawal syndrome." | 1.25 | Biogenic amines and head twitches in mice during ethanol withdrawal. ( Collier, HO; Hammond, MD; Schneider, C, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 90 (40.91) | 18.7374 |
| 1990's | 38 (17.27) | 18.2507 |
| 2000's | 59 (26.82) | 29.6817 |
| 2010's | 32 (14.55) | 24.3611 |
| 2020's | 1 (0.45) | 2.80 |
| Authors | Studies |
|---|---|
| Bray, B | 2 |
| Clement, KA | 1 |
| Bachmeier, D | 1 |
| Weber, MA | 1 |
| Forster, GL | 8 |
| Haj-Mirzaian, A | 3 |
| Amiri, S | 2 |
| Amini-Khoei, H | 2 |
| Hashemiaghdam, A | 1 |
| Ramezanzadeh, K | 1 |
| Ghesmati, M | 1 |
| Afshari, K | 1 |
| Dehpour, AR | 1 |
| Popkin, S | 1 |
| Nanchanatt, A | 1 |
| Mauterer, MI | 1 |
| Rhoads, DE | 1 |
| Rincón-Cortés, M | 1 |
| Gagnon, KG | 1 |
| Dollish, HK | 2 |
| Grace, AA | 4 |
| Dias, VT | 1 |
| Rosa, HZ | 1 |
| D'avila, LF | 1 |
| Vey, LT | 1 |
| Barcelos, RCS | 2 |
| Burger, ME | 2 |
| Koltunowska, D | 2 |
| Gibula-Bruzda, E | 3 |
| Kotlinska, JH | 3 |
| Calabrese, F | 1 |
| Richetto, J | 2 |
| Racagni, G | 1 |
| Feldon, J | 14 |
| Meyer, U | 2 |
| Riva, MA | 2 |
| Gill, KM | 1 |
| Cook, JM | 1 |
| Poe, MM | 1 |
| Jones, CG | 1 |
| Yang, PB | 1 |
| Wilcox, VT | 1 |
| Burau, KD | 1 |
| Dafny, N | 1 |
| Renard, GM | 1 |
| Sotomayor-Zarate, R | 1 |
| Blanco, EH | 1 |
| Gysling, K | 1 |
| Reinbold, ED | 1 |
| Scholl, JL | 6 |
| Oliver, KM | 2 |
| Watt, MJ | 5 |
| Li, H | 1 |
| Tu, W | 3 |
| Hassell, JE | 1 |
| Renner, KJ | 5 |
| Cook, A | 1 |
| Mears, M | 1 |
| Belujon, P | 1 |
| Jakobowski, NL | 1 |
| Segat, HJ | 1 |
| Martini, F | 1 |
| Brüning, CA | 1 |
| Nogueira, CW | 1 |
| Kang, S | 1 |
| Paul, K | 1 |
| Hankosky, ER | 1 |
| Cox, CL | 1 |
| Gulley, JM | 2 |
| Marszalek-Grabska, M | 1 |
| Jenda, M | 1 |
| Gawel, K | 1 |
| Alijanpour, S | 1 |
| Tirgar, F | 1 |
| Rahimi-Balaei, M | 1 |
| Rastegar, M | 1 |
| Ghaderi, M | 1 |
| Ghazi-Khansari, M | 1 |
| Zarrindast, MR | 1 |
| White, W | 3 |
| White, IM | 3 |
| Engelke, DS | 1 |
| Filev, R | 1 |
| Mello, LE | 1 |
| Santos-Junior, JG | 1 |
| Ligeiro de Oliveira, AP | 1 |
| Lazzarini, R | 1 |
| Cavriani, G | 1 |
| Quinteiro-Filho, WM | 1 |
| Tavares de Lima, W | 1 |
| Palermo-Neto, J | 1 |
| Negus, SS | 1 |
| Rice, KC | 1 |
| Jayaram-Lindström, N | 1 |
| Hammarberg, A | 1 |
| Beck, O | 1 |
| Franck, J | 1 |
| Lorenc-Koci, E | 1 |
| Antkiewicz-Michaluk, L | 1 |
| Kamińska, A | 1 |
| Lenda, T | 1 |
| Zieba, B | 1 |
| Wierońska, J | 1 |
| Smiałowska, M | 1 |
| Schulze, G | 2 |
| Rommelspacher, H | 1 |
| Harrison, SJ | 1 |
| Nobrega, JN | 1 |
| Horner, KA | 1 |
| Noble, ES | 1 |
| Lauterbach, EC | 1 |
| Nelson, CL | 1 |
| Milovanovic, M | 1 |
| Wetter, JB | 1 |
| Ford, KA | 1 |
| Wolf, ME | 3 |
| Peleg-Raibstein, D | 3 |
| Yee, BK | 2 |
| Hauser, J | 1 |
| Shoptaw, SJ | 1 |
| Kao, U | 1 |
| Heinzerling, K | 1 |
| Ling, W | 1 |
| Harris, DS | 1 |
| Everhart, T | 1 |
| Jacob, P | 1 |
| Lin, E | 1 |
| Mendelson, JE | 1 |
| Jones, RT | 1 |
| Vuong, SM | 1 |
| Oliver, HA | 1 |
| Der-Avakian, A | 1 |
| Markou, A | 9 |
| Semenova, S | 2 |
| Barr, JL | 2 |
| Byrnes, JJ | 1 |
| Bridges, RS | 1 |
| Byrnes, EM | 1 |
| Shabanov, PD | 1 |
| Lebedev, AA | 1 |
| Fukushiro, DF | 1 |
| Mári-Kawamoto, E | 1 |
| Aramini, TC | 1 |
| Saito, LP | 1 |
| Costa, JM | 1 |
| Josino, FS | 1 |
| Frussa-Filho, R | 2 |
| Raoof, H | 1 |
| Suder, P | 1 |
| Silberring, J | 1 |
| Solanki, RR | 1 |
| Lowry, CA | 1 |
| Che, Y | 1 |
| Cui, YH | 1 |
| Tan, H | 1 |
| Andreazza, AC | 1 |
| Young, LT | 1 |
| Wang, JF | 1 |
| Krall, DM | 1 |
| Lim, SL | 1 |
| Cooper, AM | 1 |
| Burleson, PW | 1 |
| Rhoades, DJ | 1 |
| Jacquemin, SJ | 1 |
| Willmore, DC | 1 |
| Spears, FM | 1 |
| Willmore, CB | 1 |
| Hsieh, HC | 1 |
| Li, HY | 1 |
| Lin, MY | 1 |
| Chiou, YF | 1 |
| Lin, SY | 1 |
| Wong, CH | 1 |
| Chen, JC | 3 |
| Lin, D | 2 |
| Bruijnzeel, AW | 1 |
| Schmidt, P | 1 |
| Sokolov, BP | 1 |
| Polesskaya, OO | 1 |
| Uhl, GR | 3 |
| Russig, H | 6 |
| Pezze, MA | 2 |
| Nanz-Bahr, NI | 1 |
| Pryce, CR | 1 |
| Murphy, CA | 7 |
| Magendzo, K | 1 |
| Bustos, G | 1 |
| Durrer, A | 1 |
| Cryan, JF | 1 |
| Hoyer, D | 2 |
| PROUT, CT | 1 |
| MANSON, IW | 1 |
| McMahon, LR | 2 |
| Sell, SL | 3 |
| France, CP | 3 |
| Yin, HS | 1 |
| Chen, CT | 1 |
| Lin, TY | 1 |
| Faleiro, LJ | 1 |
| Jones, S | 1 |
| Kauer, JA | 1 |
| Mohila, CA | 1 |
| Onn, SP | 2 |
| Harrison, AA | 2 |
| Chevrette, J | 1 |
| Chrostek Maj, J | 1 |
| Kroch, S | 1 |
| Kamenczak, A | 1 |
| Polewka, A | 1 |
| Szerszeń-Motyka, J | 1 |
| Barrett, RJ | 4 |
| Caul, WF | 4 |
| Smith, RL | 1 |
| McCracken, CB | 1 |
| Patel, KM | 1 |
| Vrana, KE | 1 |
| Paul, DL | 1 |
| Roberts, DC | 1 |
| Koek, W | 1 |
| Tenn, CC | 2 |
| Fletcher, PJ | 2 |
| Kapur, S | 2 |
| Martinez, V | 1 |
| Parikh, V | 1 |
| Sarter, M | 1 |
| Smith, R | 1 |
| Sydekum, E | 1 |
| Peterson, JD | 1 |
| White, FJ | 1 |
| Homayoun, H | 1 |
| Moghaddam, B | 1 |
| Vacca, G | 1 |
| Ahn, S | 1 |
| Phillips, AG | 2 |
| Schwabe, K | 1 |
| Koch, M | 1 |
| Sinyard, J | 1 |
| Rizos, Z | 1 |
| Costa, FG | 1 |
| Canteras, NS | 1 |
| Valera, AG | 1 |
| Felicio, LF | 1 |
| Raffa, RB | 2 |
| Stagliano, GW | 1 |
| Ross, G | 1 |
| Powell, JA | 1 |
| Ding, Z | 2 |
| Rawls, SM | 2 |
| Cavallo, F | 1 |
| Capasso, A | 1 |
| Stanis, JJ | 1 |
| Marquez Avila, H | 1 |
| White, MD | 1 |
| Maffii, G | 1 |
| Banfi, S | 1 |
| Kramer, JC | 1 |
| Fischman, VS | 1 |
| Littlefield, DC | 1 |
| Glassman, RB | 1 |
| Glassman, HN | 1 |
| Lake, CR | 1 |
| Quirk, RS | 1 |
| Adler, MW | 1 |
| Geller, EB | 1 |
| Jänicke, UA | 1 |
| Coper, H | 1 |
| Berglund, M | 1 |
| Risberg, J | 1 |
| Eisenberg, RM | 2 |
| Djenderedjian, A | 1 |
| Tashjian, R | 1 |
| Pierce, RC | 1 |
| Kalivas, PW | 1 |
| Wise, RA | 1 |
| Munn, E | 1 |
| Persico, AM | 2 |
| Schindler, CW | 2 |
| Zaczek, R | 1 |
| Brannock, MT | 1 |
| Crippens, D | 1 |
| Robinson, TE | 3 |
| Pulvirenti, L | 3 |
| Koob, GF | 5 |
| Paulson, PE | 2 |
| Thompson, PM | 1 |
| Gillin, JC | 1 |
| Golshan, S | 1 |
| Irwin, M | 2 |
| Garcia-Munoz, M | 1 |
| Segal, DS | 1 |
| Patino, P | 1 |
| Young, SJ | 1 |
| Kuczenski, R | 1 |
| Groves, PM | 1 |
| Lee, TH | 1 |
| Ellinwood, EH | 2 |
| King, GR | 1 |
| Bickerdike, MJ | 2 |
| Abercrombie, ED | 2 |
| Smith-Kielland, A | 1 |
| Skuterud, B | 1 |
| Mørland, J | 1 |
| Ehsan, E | 1 |
| Akerman, KE | 1 |
| Abdel Raheem, K | 1 |
| Ismael, N | 1 |
| Saad, A | 1 |
| el-Sayad, S | 1 |
| Stadler, JR | 2 |
| Huang, YH | 1 |
| Tsai, SJ | 1 |
| Wang, YC | 1 |
| Yu, MF | 1 |
| Yang, YC | 1 |
| Sim, CB | 1 |
| Davis, SC | 1 |
| Ambrosio, E | 1 |
| Bailey, CP | 1 |
| Manley, SJ | 1 |
| Watson, WP | 1 |
| Wonnacott, S | 1 |
| Molleman, A | 1 |
| Little, HJ | 1 |
| Su, HJ | 1 |
| Huang, LI | 1 |
| Hsieh, MM | 1 |
| Lacerra, C | 1 |
| Martijena, ID | 1 |
| Bustos, SG | 1 |
| Molina, VA | 1 |
| Tolliver, BK | 1 |
| Ho, LB | 1 |
| Fox, LM | 1 |
| Berger, SP | 1 |
| Srisurapanont, M | 3 |
| Jarusuraisin, N | 3 |
| Jittiwutikan, J | 2 |
| Cadoni, C | 1 |
| Di Chiara, G | 1 |
| Halladay, AK | 1 |
| Wagner, GC | 1 |
| Hsu, T | 1 |
| Sekowski, A | 1 |
| Fisher, H | 1 |
| Lu, W | 1 |
| Monteggia, LM | 1 |
| Sutton, MA | 1 |
| Karanian, DA | 1 |
| Self, DW | 1 |
| Paterson, NE | 1 |
| Myers, C | 1 |
| Liang, KW | 1 |
| Huang, YK | 1 |
| Liang, CS | 1 |
| Chiang, YC | 1 |
| Liem, YT | 1 |
| Mao, L | 1 |
| Wang, JQ | 1 |
| Di Iorio, L | 2 |
| Hédou, G | 1 |
| Pryce, C | 1 |
| Heidbreder, CA | 1 |
| Orsini, C | 1 |
| Kittirattanapaiboon, P | 1 |
| Fend, M | 1 |
| Chan-Ob, T | 1 |
| Kuntawongse, N | 1 |
| Boonyanaruthee, V | 1 |
| Way, EL | 1 |
| Iwamoto, ET | 1 |
| Khanna, S | 1 |
| Ho, IK | 1 |
| Shen, F | 1 |
| Loh, HH | 1 |
| Mamelak, M | 1 |
| Lal, H | 4 |
| Gianutsos, G | 1 |
| Puri, SK | 2 |
| Brick, J | 1 |
| Pohorecky, LA | 1 |
| Burstein, Y | 1 |
| Giardina, PJ | 1 |
| Rausen, AR | 1 |
| Kandall, SR | 1 |
| Siljestrom, K | 1 |
| Peterson, CM | 1 |
| Bhargava, HN | 1 |
| Söderholm, S | 1 |
| Viukari, NM | 1 |
| Rimón, R | 1 |
| Siever, L | 1 |
| Kraemer, H | 1 |
| Sack, R | 1 |
| Angwin, P | 1 |
| Berger, P | 1 |
| Zarcone, V | 1 |
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| Brodie, HK | 1 |
| Cottereau, MJ | 1 |
| Lôo, H | 1 |
| Poirier, MF | 1 |
| Deniker, P | 1 |
| Robins, LN | 1 |
| Helzer, JE | 1 |
| Davis, DH | 1 |
| Colpaert, FC | 1 |
| Laduron, P | 1 |
| Contreras, E | 1 |
| Tamayo, L | 1 |
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| Banerjee, U | 3 |
| Rossetti, ZL | 1 |
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| Gessa, GL | 1 |
| Bechara, A | 1 |
| van der Kooy, D | 1 |
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| Ketter, TA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long-term Phentermine Pharmacotherapy: An Investigation for Symptoms of Dependence, Cravings, or Withdrawal[NCT01402674] | 269 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
17 reviews available for amphetamine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Treatment for amphetamine withdrawal.
Topics: Amphetamine; Antidepressive Agents, Tricyclic; Dextroamphetamine; Dibenzocycloheptenes; Dopamine Upt | 2009 |
Contributions of neuropharmacology to understanding mechanisms of tolerance and dependence.
Topics: Amphetamine; Animals; Body Temperature; Drug Tolerance; Humans; Morphine; Narcotics; Pharmacology; R | 1984 |
Drug addiction: the yin and yang of hedonic homeostasis.
Topics: Amphetamine; Amygdala; Brain; Cocaine; Drug Tolerance; Homeostasis; Humans; Narcotics; Neuropeptides | 1996 |
Treatment for amphetamine withdrawal.
Topics: Amphetamine; Clinical Trials as Topic; Dextroamphetamine; Dopamine Uptake Inhibitors; Humans; Metham | 2001 |
An amphetamine model of manic depressive illness.
Topics: Adaptation, Psychological; Amphetamine; Antidepressive Agents; Bipolar Disorder; Brain; Humans; Lith | 1978 |
Monoamine oxidase inhibitor withdrawal phenomena: symptoms and pathophysiology.
Topics: Adult; Amphetamine; Female; Humans; Male; Monoamine Oxidase Inhibitors; Receptors, Neurotransmitter; | 1988 |
Chronic neuropharmacology of cocaine: progress in pharmacotherapy.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine; Humans; Methylphenidate; Psychotherapy; R | 1988 |
Drug therapy reviews: rational use of psychotropic drugs. III. Major tranquilizers.
Topics: Adrenergic alpha-Agonists; Adult; Alcoholism; Amphetamine; Antiemetics; Antipsychotic Agents; Body T | 1974 |
Rational use of psychotropic drugs. III. Major tranquilizers.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Antiemetics; Antipsychotic Agents; Basal Ganglia Diseases | 1974 |
Sleep, natural and unnatural.
Topics: Amphetamine; Antidepressive Agents; Barbiturates; Brain Chemistry; Dreams; Electroconvulsive Therapy | 1969 |
Symposium: behavior modification by drugs. I. Pharmacology of the amphetamines.
Topics: Amphetamine; Animals; Arousal; Catecholamines; Central Nervous System; Child; Child, Preschool; Cons | 1972 |
[Psychopharmacology of sleep. II].
Topics: Amphetamine; Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Humans; Hypnotics and | 1972 |
Advances in the treatment of drug addiction.
Topics: Alcoholism; Amphetamine; Aversive Therapy; Barbiturates; Heroin; Humans; Lysergic Acid Diethylamide; | 1972 |
[Neurobiologic aspects of the morphine addictions].
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Catecholamines; Cocaine; Desipram | 1974 |
Drug dependency. Investigations of stimulants and depressants.
Topics: Amphetamine; Antidepressive Agents; Cannabis; Central Nervous System; Hallucinogens; Humans; Hypnoti | 1969 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
Shazam. Or, the medical management of non-opiate drug abuse.
Topics: Adolescent; Adult; Amphetamine; Barbiturates; Cannabis; Drug Contamination; Humans; Lysergic Acid Di | 1971 |
7 trials available for amphetamine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Naltrexone for the treatment of amphetamine dependence: a randomized, placebo-controlled trial.
Topics: Adult; Amphetamine; Amphetamine-Related Disorders; Double-Blind Method; Female; Humans; Male; Middle | 2008 |
A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion.
Topics: Administration, Cutaneous; Adult; Affect; Amphetamine; Amphetamines; Analysis of Variance; Cocaine; | 2009 |
Amphetamine withdrawal: II. A placebo-controlled, randomised, double-blind study of amineptine treatment.
Topics: Adolescent; Adult; Aged; Amphetamine; Central Nervous System Stimulants; Dibenzocycloheptenes; Doubl | 1999 |
[The psychotropic effect of the Pyrovalerone (F-1983), placebo, the milieu therapy and mental condition of the patients in forensic psychiatry].
Topics: Achievement; Adolescent; Amphetamine; Attitude of Health Personnel; Clinical Trials as Topic; Forens | 1976 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
Levomethadyl in maintenance treatment of opiate dependence.
Topics: Adult; Alcohols; Amphetamine; Barbiturates; Benzene Derivatives; Heroin; Humans; Injections, Intrave | 1972 |
Studies of the dependence-producing potential of the narcotic antagonist 2-cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan (cyclazocine, WIN-20,740, ARC II-c-3).
Topics: Amphetamine; Analgesics; Barbiturates; Cannabis; Clinical Trials as Topic; Cocaine; Cyclazocine; Dru | 1965 |
197 other studies available for amphetamine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Corticosterone in the ventral hippocampus differentially alters accumbal dopamine output in drug-naïve and amphetamine-withdrawn rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Corticosterone; Dopamine; Hippocampus; Male | 2020 |
Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Depression; Disease M | 2018 |
Co-administration of amphetamine with alcohol results in decreased alcohol withdrawal severity in adolescent rats.
Topics: Alcohol Drinking; Amphetamine; Animals; Central Nervous System Stimulants; Disease Models, Animal; D | 2018 |
Diazepam reverses increased anxiety-like behavior, social behavior deficit, and dopamine dysregulation following withdrawal from acute amphetamine.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anxiety; Central Nervous System Stimulants; Diazepam; Dop | 2018 |
Modafinil reduces amphetamine preference and prevents anxiety-like symptoms during drug withdrawal in young rats: Involvement of dopaminergic targets in VTA and striatum.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Anxiety; Central Nervous System Stimulants; Cor | 2019 |
The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats.
Topics: Acamprosate; Amphetamine; Animals; Anxiety; Bridged Bicyclo Compounds; Dose-Response Relationship, D | 2013 |
Effects of withdrawal from repeated amphetamine exposure in peri-puberty on neuroplasticity-related genes in mice.
Topics: Amphetamine; Animals; Blotting, Western; Brain Chemistry; Brain-Derived Neurotrophic Factor; Central | 2013 |
Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia.
Topics: Allosteric Regulation; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Diazepam; Disea | 2014 |
Acute and chronic psychostimulant treatment modulates the diurnal rhythm activity pattern of WKY female adolescent rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Circadian Rhythm; Female; Motor Activity; P | 2014 |
Withdrawal from chronic amphetamine reduces dopamine transmission in the rat lateral septum.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Disease Models, Anima | 2014 |
Central CRF2 receptor antagonism reduces anxiety states during amphetamine withdrawal.
Topics: Amphetamine; Animals; Anxiety; Infusions, Intraventricular; Male; Motor Activity; Peptide Fragments; | 2014 |
Serotonergic responses to stress are enhanced in the central amygdala and inhibited in the ventral hippocampus during amphetamine withdrawal.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Central Amygdaloid Nucleus; Central Nervous Sys | 2014 |
Serotonin in the ventral hippocampus modulates anxiety-like behavior during amphetamine withdrawal.
Topics: 5,7-Dihydroxytryptamine; Amphetamine; Amphetamine-Related Disorders; Animals; Anxiety; Central Nervo | 2014 |
Withdrawal from Acute Amphetamine Induces an Amygdala-Driven Attenuation of Dopamine Neuron Activity: Reversal by Ketamine.
Topics: Action Potentials; Amphetamine; Amphetamine-Related Disorders; Animals; Basolateral Nuclear Complex; | 2016 |
m-Trifluoromethyl-diphenyldiselenide as a pharmacological tool to treat preference symptoms related to AMPH-induced dependence in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Association Learning; Choice Behavior; Conditio | 2016 |
D1 receptor-mediated inhibition of medial prefrontal cortex neurons is disrupted in adult rats exposed to amphetamine in adolescence.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Amphetamine-Related Disorde | 2016 |
Memantine improves memory impairment and depressive-like behavior induced by amphetamine withdrawal in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Antidepressive Agents; Central Nervous System S | 2016 |
NMDA receptors are involved in the antidepressant-like effects of capsaicin following amphetamine withdrawal in male mice.
Topics: Amphetamine; Animals; Antidepressive Agents; Capsaicin; Central Nervous System Stimulants; Depressiv | 2016 |
Amphetamine withdrawal differentially affects hippocampal and peripheral corticosterone levels in response to stress.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amphetamine; Animals; Carbohydrate Dehydrogenases; Cent | 2016 |
Amphetamine and morphine may produce acute-withdrawal related hypoactivity by initially activating a common dopamine pathway.
Topics: Amphetamine; Animals; Benzazepines; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Agents; Dr | 2016 |
Evidence of memory generalization in contextual locomotor sensitization induced by amphetamine.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Disease Models, Anima | 2017 |
Effects of single or repeated amphetamine treatment and withdrawal on lung allergic inflammation in rats.
Topics: Alveolitis, Extrinsic Allergic; Amphetamine; Animals; Antipsychotic Agents; Bone Marrow Cells; Bronc | 2008 |
Mechanisms of withdrawal-associated increases in heroin self-administration: pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys.
Topics: Adrenergic Agents; Adrenergic Agonists; Amphetamine; Animals; Behavior, Addictive; Choice Behavior; | 2009 |
The influence of acute and chronic administration of 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline on the function of the nigrostriatal dopaminergic system in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dopamine; Dopamine Uptake | 2008 |
Differential susceptibility to ethanol and amphetamine sensitization in dopamine D3 receptor-deficient mice.
Topics: Alcoholic Intoxication; Amphetamine; Amphetamine-Related Disorders; Animals; Autoradiography; Behavi | 2009 |
Differential regulation of prodynophin, c-fos, and serotonin transporter mRNA following withdrawal from a chronic, escalating dose regimen of D-amphetamine.
Topics: Amphetamine; Animals; Autoradiography; Brain; Brain Mapping; Dose-Response Relationship, Drug; Enkep | 2009 |
Behavioral sensitization to amphetamine is not accompanied by changes in glutamate receptor surface expression in the rat nucleus accumbens.
Topics: Amphetamine; Animals; Cell Membrane; Gene Expression Regulation; Male; Nucleus Accumbens; Rats; Rats | 2009 |
The amphetamine sensitization model of schizophrenia: relevance beyond psychotic symptoms?
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Di | 2009 |
Increased anxiety-like behavior of rats during amphetamine withdrawal is reversed by CRF2 receptor antagonism.
Topics: Amphetamine; Animals; Anxiety; Behavior, Animal; Central Nervous System Stimulants; Male; Maze Learn | 2010 |
Withdrawal from chronic exposure to amphetamine, but not nicotine, leads to an immediate and enduring deficit in motivated behavior without affecting social interaction in rats.
Topics: Amphetamine; Animals; Body Weight; Central Nervous System Stimulants; Conditioning, Operant; Depress | 2010 |
The alpha2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Brain; | 2010 |
Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus.
Topics: Amphetamine; Analysis of Variance; Animals; Anxiety; Cell Count; Cell Death; Corticosterone; Dentate | 2010 |
Amphetamine sensitization in reproductively experienced female rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Dopamine Uptake Inhibitors; Dose-Response Relat | 2011 |
[Behavioral correlations of gradual forced administration of psychoactive drugs].
Topics: Amphetamine; Animals; Anxiety; Behavior, Animal; Dexamethasone; Dose-Response Relationship, Drug; Dr | 2011 |
Withdrawal from repeated treatment with amphetamine reduces novelty-seeking behavior and enhances environmental habituation in mice.
Topics: Amphetamine; Animals; Environment; Exploratory Behavior; Habituation, Psychophysiologic; Male; Mice; | 2011 |
Modulation of neuropeptide FF (NPFF) receptors influences the expression of amphetamine-induced conditioned place preference and amphetamine withdrawal anxiety-like behavior in rats.
Topics: Adamantane; Amphetamine; Animals; Anxiety; Behavior, Animal; Conditioning, Psychological; Dipeptides | 2012 |
Comparison of the long-term consequences of withdrawal from repeated amphetamine exposure in adolescence and adulthood on information processing and locomotor sensitization in mice.
Topics: Age Factors; Aging; Amphetamine; Animals; Association Learning; Central Nervous System Sensitization | 2013 |
Influence of chronic amphetamine treatment and acute withdrawal on serotonin synthesis and clearance mechanisms in the rat ventral hippocampus.
Topics: Amphetamine; Animals; Gene Expression; Hippocampus; Male; Organic Cation Transport Proteins; Rats; R | 2013 |
Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Depression; Disease Mo | 2013 |
Withdrawal effect of chronic amphetamine exposure during adolescence on complex maze performance.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Male; Maze Learning; Rats | 2014 |
Spatial and temporal profile of haloperidol-induced immediate-early gene expression and phosphoCREB binding in the dorsal and ventral striatum of amphetamine-sensitized rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Basal Ganglia; Cyclic AMP Response Element-Bind | 2002 |
Exposure to chronic mild stress alters thresholds for lateral hypothalamic stimulation reward and subsequent responsiveness to amphetamine.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Chronic Dise | 2002 |
Mouse brain gene expression changes after acute and chronic amphetamine.
Topics: Amphetamine; Animals; Brain; Brain Chemistry; Drug Administration Schedule; Gene Expression Profilin | 2003 |
Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests.
Topics: Adrenocorticotropic Hormone; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulan | 2003 |
Expression of amphetamine-induced behavioral sensitization after short- and long-term withdrawal periods: participation of mu- and delta-opioid receptors.
Topics: Amphetamine; Animals; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors | 2003 |
The acquisition, retention and reversal of spatial learning in the morris water maze task following withdrawal from an escalating dosage schedule of amphetamine in wistar rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Drug Administration Schedule; Escape Reacti | 2003 |
Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Central Nervous System Stimul | 2003 |
REACTIONS TO USE OF AMPHETAMINES AS OBSERVED IN A PSYCHIATRIC HOSPITAL.
Topics: Alcoholism; Amobarbital; Amphetamine; Amphetamines; Barbiturates; Dextroamphetamine; Hospitals, Psyc | 1964 |
TO-DAY'S DRUGS. DRUGS OF ADDICTION. 2.
Topics: Accidents; Accidents, Occupational; Amphetamine; Amphetamines; Behavior, Addictive; Humans; Substanc | 1964 |
Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys.
Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal; | 2004 |
Clozapine treatment attenuated somatic and affective signs of nicotine and amphetamine withdrawal in subsets of rats exhibiting hyposensitivity to the initial effects of clozapine.
Topics: Affective Symptoms; Amphetamine; Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationshi | 2003 |
Age- and region-dependent alterations in the GABAergic innervation in the brain of rats treated with amphetamine.
Topics: Aging; Amphetamine; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; gamma-Amino | 2004 |
Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; | 2004 |
Increases in the density of parvalbumin-immunoreactive neurons in anterior cingulate cortex of amphetamine-withdrawn rats: evidence for corticotropin-releasing factor in sustained elevation.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Calbindin 1; Calbindin 2; Calbindins; Calcium-B | 2005 |
Development of acute withdrawal during periodic administration of amphetamine in rats.
Topics: Acute Disease; Amphetamine; Animals; Central Nervous System Stimulants; Circadian Rhythm; Light; Mal | 2004 |
Paroxetine combined with a 5-HT(1A) receptor antagonist reversed reward deficits observed during amphetamine withdrawal in rats.
Topics: Affective Symptoms; Aminopyridines; Amphetamine; Animals; Brain; Drug Synergism; Hypothalamus, Poste | 2005 |
[Assessment of disorders after chronic psychoactive drug abuse in patients hospitalized in detoxification units].
Topics: Adolescent; Adult; Amphetamine; Amphetamine-Related Disorders; Cannabis; Cocaine; Cocaine-Related Di | 2004 |
Evidence for bidirectional cues as a function of time following treatment with amphetamine: implications for understanding tolerance and withdrawal.
Topics: Amphetamine; Animals; Cues; Dose-Response Relationship, Drug; Drug Tolerance; Male; Rats; Rats, Spra | 2004 |
Amphetamine withdrawal produces region-specific and time-dependent changes in connexin36 expression in rat brain.
Topics: Amphetamine; Animals; Brain; Connexins; Gap Junction delta-2 Protein; Gene Expression Regulation, En | 2005 |
Monoaminergic drugs and directly observable signs of LAAM withdrawal in rhesus monkeys.
Topics: Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Animals; Antidepressive Agents, Tricycli | 2005 |
A putative animal model of the "prodromal" state of schizophrenia.
Topics: Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Anim | 2005 |
Sensitized attentional performance and Fos-immunoreactive cholinergic neurons in the basal forebrain of amphetamine-pretreated rats.
Topics: Amphetamine; Animals; Attention; Basal Nucleus of Meynert; Cell Count; Central Nervous System Stimul | 2005 |
Withdrawal, tolerance, and sensitization to dopamine mediated interoceptive cues in rats trained on a three-lever drug-discrimination task.
Topics: Amphetamine; Animals; Cues; Discrimination Learning; Dopamine; Dopamine Agonists; Dopamine Antagonis | 2005 |
Behavioural consequences of withdrawal from three different administration schedules of amphetamine.
Topics: Amphetamine; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Central Nervous System Stimul | 2005 |
An activity indicator of acute withdrawal depends on amphetamine dose in rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Circadian Rhythm; Darkness; Dose-Response R | 2006 |
Withdrawal from continuous amphetamine administration abolishes latent inhibition but leaves prepulse inhibition intact.
Topics: Acoustic Stimulation; Amphetamine; Animals; Disease Models, Animal; Inhibition, Psychological; Male; | 2006 |
Repeated amphetamine administration decreases D1 dopamine receptor-mediated inhibition of voltage-gated sodium currents in the prefrontal cortex.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Cyclic AMP-Dependent Protein Kinases; Disease M | 2006 |
Progression of cellular adaptations in medial prefrontal and orbitofrontal cortex in response to repeated amphetamine.
Topics: Action Potentials; Adaptation, Physiological; Amphetamine; Amphetamine-Related Disorders; Animals; C | 2006 |
Effects of short-term abstinence from escalating doses of D-amphetamine on drug and sucrose-evoked dopamine efflux in the rat nucleus accumbens.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Chromatograp | 2007 |
Effects of aripiprazole on operant responding for a natural reward after psychostimulant withdrawal in rats.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Central Nervous System S | 2007 |
A sensitizing regimen of amphetamine impairs visual attention in the 5-choice serial reaction time test: reversal by a D1 receptor agonist injected into the medial prefrontal cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Attention; Cogniti | 2007 |
Blockade of neurotensin receptors during amphetamine discontinuation indicates individual variability.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Exploratory | 2007 |
Effects of withdrawal from an escalating dose of amphetamine on conditioned fear and dopamine response in the medial prefrontal cortex.
Topics: Amphetamine; Analysis of Variance; Animals; Association Learning; Conditioning, Classical; Dopamine; | 2008 |
The kappa-opioid receptor antagonist nor-BNI inhibits cocaine and amphetamine, but not cannabinoid (WIN 52212-2), abstinence-induced withdrawal in planarians: an instance of 'pharmacologic congruence'.
Topics: Amphetamine; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Benzoxazines; Cocaine; Dis | 2008 |
The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Anti-Bacterial Agents; Ceftriaxone; Clorazepate | 2008 |
Dissociation between long-lasting behavioral sensitization to amphetamine and impulsive choice in rats performing a delay-discounting task.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Choice Behavior; Conditioning, Operant; Foo | 2008 |
[Experimental observations on addiction and abstinence phenomena in the rat treated with analgesics].
Topics: Amphetamine; Analgesics; Animals; Cocaine; Humans; Rats; Substance Withdrawal Syndrome; Substance-Re | 1966 |
Amphetamine abuse. Pattern and effects of high doses taken intravenously.
Topics: Adolescent; Adult; Amphetamine; Drug Tolerance; Humans; Injections, Intravenous; Orientation; Parano | 1967 |
Narcotics and medical practice. Medical use of morphine and morphine-like drugs and management of persons dependent on them.
Topics: Amphetamine; Barbiturates; Cannabis; Drug and Narcotic Control; Female; Heroin; Humans; Legislation, | 1967 |
Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Di | 1980 |
CNS stimulants and the look-alike drugs.
Topics: Amphetamine; Caffeine; Central Nervous System Stimulants; Depressive Disorder; Ephedrine; Humans; Il | 1984 |
(+)-Amphetamine oral 'drug taking behavior' in naive and tolerant rats.
Topics: Administration, Oral; Amphetamine; Animals; Drinking; Drug Tolerance; Eating; Humans; Male; Motor Ac | 1984 |
Regional cerebral blood flow in a case of amphetamine intoxication.
Topics: Adult; Amphetamine; Cerebrovascular Circulation; Humans; Male; Substance Withdrawal Syndrome | 1980 |
Further studies on the acute dependence produced by morphine in opiate naive rats.
Topics: Amphetamine; Animals; Corticosterone; Diazepam; Drug Tolerance; Humans; Male; Morphine; Morphine Dep | 1982 |
Agoraphobia following amphetamine withdrawal.
Topics: Adult; Agoraphobia; Amphetamine; Female; Humans; Obesity; Phobic Disorders; Substance Withdrawal Syn | 1982 |
Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Behavior, Animal; | 1995 |
Withdrawal from chronic amphetamine elevates baseline intracranial self-stimulation thresholds.
Topics: Amphetamine; Animals; Brain; Dextroamphetamine; Dose-Response Relationship, Drug; Hypothalamic Area, | 1995 |
Brain transcription factor gene expression, neurotransmitter levels, and novelty response behaviors: alterations during rat amphetamine withdrawal and following chronic injection stress.
Topics: Amphetamine; Animals; Biogenic Amines; Brain; Exploratory Behavior; Gene Expression; Injections; Mal | 1995 |
Withdrawal from morphine or amphetamine: different effects on dopamine in the ventral-medial striatum studied with microdialysis.
Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Male; Microdialysis; Morphine; Rats; Rats, Sprague- | 1994 |
Lisuride reduces psychomotor retardation during withdrawal from chronic intravenous amphetamine self-administration in rats.
Topics: Amphetamine; Animals; Catalepsy; Lisuride; Male; Motor Activity; Rats; Rats, Wistar; Self Administra | 1993 |
Regional differences in the effects of amphetamine withdrawal on dopamine dynamics in the striatum. Analysis of circadian patterns using automated on-line microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Circadian Rhythm; Dopamine; F | 1996 |
Polygraphic sleep measures differentiate alcoholics and stimulant abusers during short-term abstinence.
Topics: Acute Disease; Adult; Alcoholism; Amphetamine; Cocaine; Ethanol; Humans; Illicit Drugs; Male; Middle | 1995 |
Amphetamine-induced changes in nigrostriatal terminal excitability are modified following repeated amphetamine pretreatment.
Topics: Amphetamine; Animals; Axons; Basal Ganglia; Central Nervous System Stimulants; Electrophysiology; Ma | 1996 |
Regional differences in the effects of amphetamine withdrawal on dopamine dynamics in the striatum.
Topics: Amphetamine; Animals; Dopamine; Dopamine Uptake Inhibitors; Rats; Substance Withdrawal Syndrome | 1997 |
Striatal acetylcholine release correlates with behavioral sensitization in rats withdrawn from chronic amphetamine.
Topics: Acetylcholine; Amphetamine; Animals; Corpus Striatum; Male; Microdialysis; Motor Activity; Rats; Rat | 1997 |
Urinary excretion of amphetamine after termination of drug abuse.
Topics: Adolescent; Adult; Amphetamine; Amphetamine-Related Disorders; Creatinine; Female; Gas Chromatograph | 1997 |
Effect of morphine on rotational behavior of unilaterally brain-lesioned mice and rats: morphine withdrawal and development of tolerance.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Drug Tolerance; Functiona | 1997 |
Gluconeogenic activity in response to chronic administration of amphetamine sulphate and drug withdrawal.
Topics: Adrenocorticotropic Hormone; Alanine Transaminase; Amphetamine; Animals; Aspartate Aminotransferases | 1997 |
Amphetamine-induced withdrawal responding: effects of repeated drug administration.
Topics: Amphetamine; Animals; Conditioning, Operant; Discrimination Learning; Dopamine Antagonists; Dopamine | 1997 |
Differential development of the enhanced metabolic response during amphetamine sensitization.
Topics: Amphetamine; Animals; Antimetabolites; Brain Chemistry; Central Nervous System Stimulants; Deoxygluc | 1997 |
Medial prefrontal cortical injections of c-fos antisense oligonucleotides transiently lower c-Fos protein and mimic amphetamine withdrawal behaviours.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Half-Life; Immunohistoche | 1998 |
Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability.
Topics: Action Potentials; Amphetamine; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Ethanol; Hyperk | 1998 |
Reductions in binding and functions of D2 dopamine receptors in the rat ventral striatum during amphetamine sensitization.
Topics: Adenylyl Cyclases; Amphetamine; Analysis of Variance; Animals; Bromocriptine; Colforsin; Corpus Stri | 1999 |
Benzodiazepine withdrawal facilitates the subsequent onset of escape failures and anhedonia: influence of different antidepressant drugs.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Avoidance Learning; Conditioning, | 1999 |
Necessary role for ventral tegmental area adenylate cyclase and protein kinase A in induction of behavioral sensitization to intraventral tegmental area amphetamine.
Topics: Adenylyl Cyclases; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cyclic | 1999 |
Enhanced acetylcholine release in striatum after chronic amphetamine is NMDA-dependent.
Topics: Acetylcholine; Amphetamine; Animals; Corpus Striatum; Dopamine Agonists; Male; Rats; Rats, Sprague-D | 1999 |
Amphetamine withdrawal: I. Reliability, validity and factor structure of a measure.
Topics: Adolescent; Adult; Aged; Amphetamine; Female; Humans; Male; Middle Aged; Reproducibility of Results; | 1999 |
Reciprocal changes in dopamine responsiveness in the nucleus accumbens shell and core and in the dorsal caudate-putamen in rats sensitized to morphine.
Topics: Amphetamine; Animals; Catalepsy; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; Grooming; Ma | 1999 |
Characterizing withdrawal in rats following repeated drug administration using an amphetamine-vehicle-haloperidol drug discrimination.
Topics: Amphetamine; Animals; Discrimination Learning; Dopamine Agents; Dopamine Antagonists; Haloperidol; I | 1999 |
Differential effects of monoaminergic agonists on alcohol intake in rats fed a tryptophan-enhanced diet.
Topics: Alcohol Drinking; Amphetamine; Animals; Appetite Depressants; Cerebral Cortex; Corpus Striatum; Dopa | 1999 |
Differential effects of withdrawal from chronic amphetamine or fluoxetine administration on brain stimulation reward in the rat--interactions between the two drugs.
Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Drug Interactions; Fluoxetine; Male; | 1999 |
Withdrawal from repeated amphetamine administration reduces NMDAR1 expression in the rat substantia nigra, nucleus accumbens and medial prefrontal cortex.
Topics: Amphetamine; Animals; Autoradiography; Central Nervous System Stimulants; Image Interpretation, Comp | 1999 |
Amphetamine withdrawal alters bistable states and cellular coupling in rat prefrontal cortex and nucleus accumbens neurons recorded in vivo.
Topics: Action Potentials; Amphetamine; Amphetamine-Related Disorders; Animals; Antibodies; Brain Chemistry; | 2000 |
Factors that determine a propensity for cocaine-seeking behavior during abstinence in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dose-Response Relationsh | 2000 |
Effects of repeated withdrawal from continuous amphetamine administration on brain reward function in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Brain; Central Nervous System Stimulants; Depre | 2000 |
Significance of glutamate and dopamine neurons in the ventral pallidum in the expression of behavioral sensitization to amphetamine.
Topics: Amphetamine; Animals; Aspartic Acid; Behavior, Animal; Central Nervous System Stimulants; Dizocilpin | 2001 |
Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats.
Topics: Aminopyridines; Amphetamine; Amphetamine-Related Disorders; Animals; Body Weight; Brain; Depression; | 2001 |
Differentially altered mGluR1 and mGluR5 mRNA expression in rat caudate nucleus and nucleus accumbens in the development and expression of behavioral sensitization to repeated amphetamine administration.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Caudate Nucleus; Central Nerv | 2001 |
Effects of psychostimulant withdrawal on latent inhibition of conditioned active avoidance and prepulse inhibition of the acoustic startle response.
Topics: Acoustic Stimulation; Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Central Nervous Sy | 2001 |
An automated analysis of rat behavior in the forced swim test.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Male; Rats; Rats, Sprag | 2001 |
Dopamine partial agonist reverses amphetamine withdrawal in rats.
Topics: Amphetamine; Animals; Conditioning, Operant; Dopamine Agonists; Dopamine Uptake Inhibitors; Lisuride | 2001 |
Latent inhibition, but not prepulse inhibition, is reduced during withdrawal from an escalating dosage schedule of amphetamine.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Disease Models, Animal; Inhibition, Psychol | 2001 |
Increased conditioned fear response and altered balance of dopamine in the shell and core of the nucleus accumbens during amphetamine withdrawal.
Topics: Amphetamine; Animals; Conditioning, Psychological; Dopamine; Dopamine Uptake Inhibitors; Extracellul | 2002 |
Bupropion for amphetamine withdrawal syndrome.
Topics: Adolescent; Amphetamine; Antidepressive Agents, Second-Generation; Bupropion; Humans; Male; Substanc | 2001 |
Clozapine and haloperidol reinstate latent inhibition following its disruption during amphetamine withdrawal.
Topics: Amphetamine; Animals; Antipsychotic Agents; Avoidance Learning; Central Nervous System Stimulants; C | 2002 |
Cocaine and amphetamine attenuate the discriminative stimulus effects of naltrexone in opioid-dependent rhesus monkeys.
Topics: Amphetamine; Animals; Cocaine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Respo | 2002 |
Precipitation of abstinence-like syndrome in morphine-dependent mice by pargyline.
Topics: Amantadine; Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism | 1976 |
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Cataleps | 1975 |
Ethanol withdrawal: altered ambient temperature selection in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Body Temperature; Choice Behavior; Decision Making; Ethanol; | 1977 |
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
Topics: Amphetamine; Cocaine; Diazepam; Female; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant, | 1979 |
Time course of the effects of naturally occurring cannabinoids on morphine abstinence syndrome.
Topics: Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Dronabinol; Humans; Levodo | 1978 |
Gradients of biogenic amine metabolites in cerebrospinal fluid.
Topics: Alzheimer Disease; Amphetamine; Brain Diseases; Brain Neoplasms; Depression; Homovanillic Acid; Huma | 1975 |
[Pharmacopsychoses during drug addiction].
Topics: Amphetamine; Atropine Derivatives; Cannabis; Cocaine; Delusions; Ether; Humans; Hypnotics and Sedati | 1975 |
Narcotic use in southeast Asia and afterward. An interview study of 898 Vietnam returnees.
Topics: Age Factors; Alcohol Drinking; Amphetamine; Barbiturates; Cannabis; Heroin; Humans; Injections, Intr | 1975 |
Narcotic withdrawal like mouse jumping produced by amphetamine and L-DOPA.
Topics: Amphetamine; Animals; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Fluorometry; Haloperidol; H | 1975 |
Sensitivity changes to morphine and other drugs induced by cholinergic blockade.
Topics: Amphetamine; Analgesics; Animals; Arecoline; Atropine; Drug Tolerance; Female; Hexobarbital; Humans; | 1975 |
Treatment of reactions to amphetamine-type stimulants.
Topics: Amphetamine; Humans; Psychoses, Substance-Induced; Substance Withdrawal Syndrome; Substance-Related | 1975 |
Conditioned avoidance behavior in pretrained rats intermittently treated with addictive drugs.
Topics: Amphetamine; Animals; Avoidance Learning; Body Weight; Conditioning, Operant; Dose-Response Relation | 1975 |
Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Ethanol; Male; Morphi | 1992 |
Lesions of the tegmental pedunculopontine nucleus: effects on the locomotor activity induced by morphine and amphetamine.
Topics: Amphetamine; Animals; Catalepsy; Male; Morphine; Motor Activity; Naloxone; Pons; Rats; Rats, Inbred | 1992 |
Sensitization of locus ceruleus neurons during withdrawal from chronic stimulants and antidepressants.
Topics: Amphetamine; Animals; Cocaine; Desipramine; Electrophysiology; Injections, Intraperitoneal; Locus Co | 1992 |
Endocrine, immune, and neurochemical changes in rats during withdrawal from chronic amphetamine intoxication.
Topics: Adrenocorticotropic Hormone; Amphetamine; Animals; Biomarkers; Body Weight; Brain Chemistry; Cortico | 1991 |
Altered behavior and neurochemistry during short-term insulin withdrawal in streptozocin-induced diabetic rats.
Topics: Amphetamine; Animals; Diabetes Mellitus, Experimental; Dopamine; Hyperglycemia; Hypothalamo-Hypophys | 1991 |
Estradiol enhances behavioral sensitization to cocaine and amphetamine-stimulated striatal [3H]dopamine release.
Topics: Amphetamine; Animals; Body Weight; Cocaine; Corpus Striatum; Dopamine; Drug Synergism; Estradiol; Fe | 1991 |
Prescribing smokable drugs.
Topics: Administration, Inhalation; Amphetamine; Cocaine; Heroin; Humans; Methadone; Substance Abuse, Intrav | 1990 |
Time course of transient behavioral depression and persistent behavioral sensitization in relation to regional brain monoamine concentrations during amphetamine withdrawal in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Depression, Chemical; | 1991 |
Effect of enantiomers of deprenyl (selegiline) and amphetamine on physical abuse liability and cortical electrical activity in rats.
Topics: Amphetamine; Animals; Body Weight; Cerebral Cortex; Codeine; Electric Conductivity; Electroencephalo | 1990 |
Treatment of cocaine-induced panic disorder.
Topics: Adult; Agoraphobia; Amphetamine; Cocaine; Fear; Female; Humans; Male; Panic; Risk Factors; Substance | 1989 |
Cerebral correlates of depressed behavior in rats, visualized using 14C-2-deoxyglucose autoradiography.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Autoradiography; Behavior, Animal; Brain; Carbon Radiois | 1988 |
Effects of chronic treatment with diazepam, phenobarbital, or amphetamine on naloxone-precipitated morphine withdrawal.
Topics: Amphetamine; Animals; Corticosterone; Diazepam; Male; Mice; Morphine Dependence; Motor Activity; Nal | 1985 |
Amphetamine withdrawal: depression and M.H.P.G. excretion.
Topics: Amphetamine; Animals; Brain; Catechols; Depression; Glycols; Humans; Norepinephrine; Substance Withd | 1971 |
Letter: Substitute for amphetamine.
Topics: Amphetamine; Humans; Pemoline; Rhinitis, Allergic, Seasonal; Substance Withdrawal Syndrome; Substanc | 1973 |
Clinical effects on drug abuse of a conviction for a drug offence.
Topics: Adolescent; Adult; Amphetamine; Cannabis; Community Psychiatry; Drug and Narcotic Control; England; | 1974 |
Drug addiction and the newborn.
Topics: Amphetamine; Antipsychotic Agents; Barbiturates; Cannabis; Child Welfare; Chlorpromazine; Diazepam; | 1973 |
Drug abuse and the emergency room physician.
Topics: Alcoholism; Amphetamine; Antipsychotic Agents; Attitude of Health Personnel; Coma; Emergency Service | 1974 |
A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs.
Topics: Aging; Amphetamine; Animals; Anti-Anxiety Agents; Barbiturates; Body Weight; Carbon Radioisotopes; C | 1974 |
Heroin and cocaine addiction.
Topics: Adolescent; Adult; Amphetamine; Barbiturates; Cannabis; Cocaine; Dextroamphetamine; Ethanol; Female; | 1965 |
Biogenic amines and head twitches in mice during ethanol withdrawal.
Topics: 5-Hydroxytryptophan; Amphetamine; Amphetamines; Animals; Behavior, Animal; Biogenic Amines; Cerebral | 1974 |
The pharmacological basis of drug dependence.
Topics: Amphetamine; Barbiturates; Cannabis; Central Nervous System; Cocaine; Ethanol; Hallucinogens; Heroin | 1970 |
Amphetamine abuse: a "speed" trap.
Topics: Adult; Affect; Amphetamine; Arousal; Body Weight; Diagnosis, Differential; Female; Hospitalization; | 1971 |
Amphetamine withdrawal: affective state, sleep patterns, and MHPG excretion.
Topics: Adult; Affect; Amphetamine; Brain; Catechols; Depression; Electroencephalography; Female; Glycols; H | 1972 |
[Significance of catecholamines for the manifestation of morphine withdrawal in the rat].
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Desipramine; D | 1974 |
Psychoanalytic considerations of the etiology of compulsive drug use.
Topics: Affective Symptoms; Amphetamine; Barbiturates; Cocaine; Compulsive Behavior; Defense Mechanisms; Emo | 1974 |
[Obstetrical problems in drug abuse].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amphetamine; Dronabinol; Female; Humans; Infant, | 1974 |
Programmed self-administration of potentially addictive drugs in young rats and its effects on learning.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Drug Tolerance; Ethanol; Extinction, Psy | 1974 |
[Drug abuse with special reference to stimulants, tranquilizing agents, hypnotics and analgetics].
Topics: Amphetamine; Analgesics; Humans; Hypnotics and Sedatives; Substance Withdrawal Syndrome; Substance-R | 1972 |
[Objective and subjective attention disorders following polyvalent drug abuse].
Topics: Adolescent; Adult; Amphetamine; Barbiturates; Cannabis; Cocaine; Cognition Disorders; Factor Analysi | 1972 |
An appraisal of anorexiants in the treatment of obesity.
Topics: Adult; Aging; Amphetamine; Appetite Depressants; Evaluation Studies as Topic; Female; Humans; Middle | 1972 |
Surgical patients and drug abuse syndrome.
Topics: Adolescent; Adult; Aged; Amphetamine; Barbiturates; Female; Focal Infection; Hallucinogens; Humans; | 1973 |
The drug scene: acute drug syndromes.
Topics: Alcoholic Intoxication; Amphetamine; Atropa belladonna; Atropine; Barbiturates; Cannabis; Diagnosis, | 1973 |
Office treatment of barbiturate and amphetamine dependence.
Topics: Amphetamine; Barbiturates; Humans; Methods; Psychoses, Substance-Induced; Substance Withdrawal Syndr | 1973 |
Relapse to morphine use in dog.
Topics: Amphetamine; Animals; Disease Models, Animal; Dogs; Humans; Morphine; Morphine Dependence; Recurrenc | 1973 |
[Psychiatric emergencies during pregnancy and in the puerperium].
Topics: Amphetamine; Cannabis; Emergencies; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lyse | 1973 |
Treatment of overdose and withdrawal of abused drugs.
Topics: Amphetamine; Cathartics; Charcoal; Diuretics; Gastric Lavage; Hallucinogens; Humans; Hypnotics and S | 1973 |
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Me | 1973 |
Tolerance pattern of the anorexigenic action of amphetamine in rats.
Topics: Amphetamine; Animals; Drug Tolerance; Fasting; Feeding Behavior; Humans; Male; Rats; Substance Withd | 1973 |
Multiple-drug addiction in New York City in a selected population group.
Topics: Amphetamine; Barbiturates; Female; Heroin; Humans; Male; Morphine Dependence; New York City; Opium; | 1966 |
Amphetamine dependence.
Topics: Adolescent; Adult; Amphetamine; Barbiturates; Culture; Drug Prescriptions; Family Practice; Female; | 1968 |
The changing face of heroin addiction in the Haight-Ashbury.
Topics: Adolescent; Adult; Amphetamine; California; Cannabis; Child; Community Health Services; Female; Hero | 1972 |
[Emergency treatment and technic of detoxification in juvenile drug addicts].
Topics: Amphetamine; Barbiturates; Cannabis; Chlormethiazole; Cocaine; Diazepam; Emergencies; Humans; Lyserg | 1972 |
The influence of prolonged amphetamine treatment and amphetamine withdrawal on brain biogenic amine content and behaviour in the rat.
Topics: Amphetamine; Animals; Body Weight; Brain Chemistry; Central Nervous System; Cerebellum; Drug Toleran | 1971 |
Acquisition of conditioned avoidance response in rats under the influence of addicting drugs.
Topics: Amphetamine; Animals; Avoidance Learning; Conditioning, Psychological; Ethanol; Humans; Lysergic Aci | 1971 |
Morphine-withdrawal aggression: sensitization by amphetamines.
Topics: Aggression; Amphetamine; Animals; Dextroamphetamine; Humans; Hydroxylamines; Male; Methylphenidate; | 1971 |
Drug dependence and pregnancy: a review of the problems and their management.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Amphetamine; Barbiturates; Cannabis; Fema | 1970 |
Amphetamine addiction.
Topics: Adolescent; Adult; Amphetamine; Drug Utilization; Female; Humans; Male; Sex Factors; Substance Withd | 1970 |
The drug-using adolescent as a pediatric patient.
Topics: Acute Kidney Injury; Administration, Oral; Adolescent; Alkaline Phosphatase; Amenorrhea; Amphetamine | 1970 |
Diagnosis and management of reactions to drug abuse.
Topics: Amphetamine; Barbiturates; Hallucinogens; Humans; Narcotics; Substance Withdrawal Syndrome; Substanc | 1970 |
New developments in barbiturate abuse.
Topics: Adolescent; Adult; Amphetamine; Barbiturates; Drug Interactions; Female; Glutethimide; Heroin; Human | 1970 |
Drug dependence: pharmacological and physiological aspects.
Topics: Amphetamine; Animals; Barbiturates; Brain; Cannabis; Central Nervous System; Cocaine; Drug Tolerance | 1970 |
The New Haven Methadone Maintenance Program.
Topics: Adult; Amphetamine; Barbiturates; Cocaine; Community Health Services; Community Mental Health Servic | 1970 |
Amphetamines, barbiturates, LSD and cannabis: their use and misuse.
Topics: Amphetamine; Barbiturates; Cannabis; Child Behavior Disorders; Crime; Depression; Humans; Hyperkines | 1970 |
Acute toxic effects of drug abuse: diagnosis and treatment.
Topics: Amphetamine; Barbiturates; Hallucinogens; Humans; Narcotics; Poisoning; Substance Withdrawal Syndrom | 1971 |
Amphetamines: a dangerous illusion.
Topics: Amphetamine; Autonomic Nervous System; Cardiovascular System; Depression; Drug Prescriptions; Humans | 1971 |
[On amphetamine in psychiatry].
Topics: Adult; Amphetamine; Female; Humans; Male; Psychoses, Substance-Induced; Substance Withdrawal Syndrom | 1967 |
Amphetamine abuse.
Topics: Amphetamine; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders | 1968 |
Medical complications of pleasure-giving drugs.
Topics: Amphetamine; Barbiturates; Condiments; Drug Synergism; Hallucinations; Hallucinogens; Hepatitis A; H | 1969 |
Amphetamine effect on the choline concentration of human cerebrospinal fluid.
Topics: Acetylcholine; Adolescent; Adult; Amphetamine; Brain; Choline; Female; Humans; Male; Substance Withd | 1969 |