amphetamine has been researched along with Spinocerebellar Ataxias in 1 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Spinocerebellar Ataxias: A group of predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The polyglutamine disease spinocerebellar ataxia type 17 (SCA17) is a neurodegenerative disease leading to severe neurological symptoms during development." | 1.46 | Capturing schizophrenia-like prodromal symptoms in a spinocerebellar ataxia-17 transgenic rat. ( Amato, D; Bauer, P; Canneva, F; Müller, CP; Nguyen, HP; Riess, O; von Hörsten, S, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amato, D | 1 |
| Canneva, F | 1 |
| Nguyen, HP | 1 |
| Bauer, P | 1 |
| Riess, O | 1 |
| von Hörsten, S | 1 |
| Müller, CP | 1 |
1 other study available for amphetamine and Spinocerebellar Ataxias
| Article | Year |
|---|---|
Capturing schizophrenia-like prodromal symptoms in a spinocerebellar ataxia-17 transgenic rat.
Topics: Amphetamine; Animals; Disease Models, Animal; Male; Memory; Motor Activity; Prodromal Symptoms; Rats | 2017 |