amphetamine has been researched along with Schizotypal Personality Disorder in 3 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Schizotypal Personality Disorder: A personality disorder in which there are oddities of thought (magical thinking, paranoid ideation, suspiciousness), perception (illusions, depersonalization), speech (digressive, vague, overelaborate), and behavior (inappropriate affect in social interactions, frequently social isolation) that are not severe enough to characterize schizophrenia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous research has suggested that schizotypal personality disorder (SPD), a condition that shares clinical and cognitive features with schizophrenia, may be associated with elevated striatal dopamine functioning; however, there are no published studies of dopamine release within subregions of the striatum in SPD." | 5.56 | Amphetamine-induced striatal dopamine release in schizotypal personality disorder. ( Abi-Dargham, A; Hazlett, EA; Kegeles, LS; Koenigsberg, HW; McClure, MM; Modiano, YA; New, AS; Perez-Rodriguez, MM; Rosell, DR; Rothstein, EG; Siever, LJ; Slifstein, M; Thompson, JL; Xu, X, 2020) |
| "Previous research has suggested that schizotypal personality disorder (SPD), a condition that shares clinical and cognitive features with schizophrenia, may be associated with elevated striatal dopamine functioning; however, there are no published studies of dopamine release within subregions of the striatum in SPD." | 1.56 | Amphetamine-induced striatal dopamine release in schizotypal personality disorder. ( Abi-Dargham, A; Hazlett, EA; Kegeles, LS; Koenigsberg, HW; McClure, MM; Modiano, YA; New, AS; Perez-Rodriguez, MM; Rosell, DR; Rothstein, EG; Siever, LJ; Slifstein, M; Thompson, JL; Xu, X, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Thompson, JL | 1 |
| Rosell, DR | 1 |
| Slifstein, M | 1 |
| Xu, X | 1 |
| Rothstein, EG | 1 |
| Modiano, YA | 1 |
| Kegeles, LS | 1 |
| Koenigsberg, HW | 1 |
| New, AS | 1 |
| Hazlett, EA | 1 |
| McClure, MM | 1 |
| Perez-Rodriguez, MM | 1 |
| Siever, LJ | 1 |
| Abi-Dargham, A | 1 |
| Woodward, ND | 1 |
| Cowan, RL | 1 |
| Park, S | 1 |
| Ansari, MS | 1 |
| Baldwin, RM | 1 |
| Li, R | 1 |
| Doop, M | 1 |
| Kessler, RM | 1 |
| Zald, DH | 1 |
| Wonodi, I | 1 |
| Cassady, SL | 1 |
| Adami, H | 1 |
| Avila, M | 1 |
| Thaker, GK | 1 |
2 trials available for amphetamine and Schizotypal Personality Disorder
| Article | Year |
|---|---|
Correlation of individual differences in schizotypal personality traits with amphetamine-induced dopamine release in striatal and extrastriatal brain regions.
Topics: Adult; Amphetamine; Brain; Corpus Striatum; Dopamine; Female; Frontal Lobe; Humans; Individuality; M | 2011 |
Effects of repeated amphetamine administration on antisaccade in schizophrenia spectrum personality.
Topics: Adult; Amphetamine; Brain; Central Nervous System Stimulants; Cognition Disorders; Drug Administrati | 2006 |
1 other study available for amphetamine and Schizotypal Personality Disorder
| Article | Year |
|---|---|
Amphetamine-induced striatal dopamine release in schizotypal personality disorder.
Topics: Adolescent; Adult; Amphetamine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Female; Human | 2020 |