amphetamine and Poisoning studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

Excerpt	Relevance	Reference
"False positive urinalysis towards amphetamine/methamphetamine by immunoassay and presence of sympathomimetic effects may contribute to a false diagnosis of this drug poisoning."	7.79	[Acute poisoning with weight-loss dietary supplement falsely suggesting the use of amphetamine]. ( Sommerfeld, K; Tezyk, A; Zielińska-Psuja, B; Łukasik-Głebocka, M, 2013)
"Fatal amphetamine poisonings cannot be identified on the basis of the concentration in blood alone, owing to the development of tolerance and the toxicity of co-ingested substances."	7.77	Quantitative analysis of amphetamine in femoral blood from drug-poisoning deaths compared with venous blood from impaired drivers. ( Ahlner, J; Holmgren, A; Jones, AW, 2011)
"False positive urinalysis towards amphetamine/methamphetamine by immunoassay and presence of sympathomimetic effects may contribute to a false diagnosis of this drug poisoning."	3.79	[Acute poisoning with weight-loss dietary supplement falsely suggesting the use of amphetamine]. ( Sommerfeld, K; Tezyk, A; Zielińska-Psuja, B; Łukasik-Głebocka, M, 2013)
" A young alcohol abuser was referred to the Acute Poisonings Unit at Wrocław with a presumptive diagnosis of methanol poisoning."	3.73	Poisoning or primary nervous system disease?--difficulties of the differential diagnosis exemplified by four different clinical cases. ( Antończyk, A; Kochman, K; Magdalan, J; Porebska, B, 2005)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (83.67)	18.7374
1990's	1 (2.04)	18.2507
2000's	3 (6.12)	29.6817
2010's	4 (8.16)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Łukasik-Głebocka, M	1
Sommerfeld, K	1
Tezyk, A	1
Zielińska-Psuja, B	1
DERVILLEE, P	1
RAVELEAU, R	1
CARVER, GM	1
DAVIDSON, WC	1
LoVecchio, F	1
Ozimek, J	1
Sawyers, B	1
Thole, D	1
Jones, AW	1
Holmgren, A	1
Ahlner, J	1
Wittebole, X	1
Hantson, P	1
Sreenivasa, HK	1
Sugumar, K	1
RAPP, RT	1
PRETORIUS, HP	1
BECKER, WF	1
KEITER, WE	1
ARNOLD, JH	1
ZALIS, EG	2
PARMLEY, LF	1
FROMMEL, E	1
FLEURY, C	1
LEDEBUR, IV	1
BEGUIN, M	1
FAMILY, S	1
LAPOLLA, A	1
NASH, LR	1
KAPLAN, G	1
LUNDBERG, GD	1
KNUTSON, RA	1
FEDELI, M	1
LUMIA, V	1
SOLOMON, H	1
WINTER, RE	1
RIISHEDE, J	1
Magdalan, J	1
Antończyk, A	1
Kochman, K	1
Porebska, B	1
Janus, T	1
Hedetoft, C	1
Christensen, HR	1
Holmgren, P	2
Lindquist, O	2
Rauen, HM	1
Schriewer, H	1
Ferié, F	1
Greenblatt, DJ	1
Shader, RI	1
Mofenson, HC	1
Greensher, J	1
Jefferson, JW	1
Greene, MH	1
Curry, AS	1
McBay, AJ	1
Consroe, PF	1
Chapel, JL	1
Retterstol, N	1
Hirsch, CS	1
Valentour, JC	1
Adelson, L	1
Sunshine, I	1
Locket, S	1
Ruedy, J	1
Robinson, AE	1
Holder, AT	1
Cimbura, G	1
van Rossum, JM	1
Vree, TB	1
Dunlop, DM	1
Gunne, LM	1
Saldeen, T	1
Ginsberg, MD	1
Hertzman, M	1
Schmidt-Nowara, WW	1
Scott, GD	1
Dunlop, D	1
Deeths, TM	1
Breeden, JT	1
Krain, LS	1
Bucher, WH	1
Heidbreder, GA	1
Street, RL	1
Holmstedt, B	1
Alván, G	1
Sjöqvist, F	1

Article	Year
Use of the molecular adsorbent recirculating system (MARS™) for the management of acute poisoning with or without liver failure. Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:9 Topics: Acetaminophen; Acute Disease; Albumins; Amanita; Amphetamine; Calcium Channel Blockers; Cocaine; Hea	2011
[Amphetamine, ecstasy and cocaine. Clinical aspects of acute poisoning]. Ugeskrift for laeger, 1999, Dec-13, Volume: 161, Issue:50 Topics: Amphetamine; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cocaine; Cocaine-Rela	1999
The unknown poison. Pediatrics, 1974, Volume: 54, Issue:3 Topics: Age Factors; Amphetamine; Amphetamines; Atropine Derivatives; Barbiturates; Charcoal; Child; Child,	1974
Beta-adrenergic receptor blocking drugs in psychiatry. Archives of general psychiatry, 1974, Volume: 31, Issue:5 Topics: Acute Disease; Adrenergic beta-Antagonists; Alcoholism; Amphetamine; Animals; Antidepressive Agents;	1974
Toxicological findings in fatal poisonings. Clinical chemistry, 1973, Volume: 19, Issue:4 Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordi	1973
[Doping agents with centrally stimulating action. On the pharmacology, pharmacokinetics and the analytical determination of psychomotor stimulants]. Nederlands tijdschrift voor geneeskunde, 1969, Nov-01, Volume: 113, Issue:44 Topics: Amphetamine; Animals; Chromatography, Gas; Humans; Mice; Motor Activity; Poisoning; Rats; Spectrum A	1969

Article	Year
[Acute poisoning with weight-loss dietary supplement falsely suggesting the use of amphetamine]. Przeglad lekarski, 2013, Volume: 70, Issue:10 Topics: Adolescent; Amphetamine; Amphetamine-Related Disorders; Anti-Obesity Agents; Diagnosis, Differential	2013
[Barium carbonate poisoning; clinical and experimental study; antidotal effects of strychnine and ortedrine]. Revue de medecine navale (metropole et outre-mer); travaux scientifiques des medecins et pharmaciens-chimistes de la marine, 1955, Volume: 10, Issue:2 Topics: Amphetamine; Amphetamines; Barium; Carbonates; Humans; Poisoning; Strychnine	1955
Clinic on poisoning. The Journal of pediatrics, 1948, Volume: 32, Issue:2 Topics: Ambulatory Care Facilities; Amphetamine; Amphetamines; Humans; Poisoning; Poisons	1948
Outcomes after accidental pediatric ingestions of (dextro)amphetamine and methylphenidate. The American journal of emergency medicine, 2009, Volume: 27, Issue:8 Topics: Accidents; Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimul	2009
Quantitative analysis of amphetamine in femoral blood from drug-poisoning deaths compared with venous blood from impaired drivers. Bioanalysis, 2011, Volume: 3, Issue:19 Topics: Adult; Age Factors; Amphetamine; Automobile Driving; Diagnosis; Female; Femur; Humans; Male; Middle	2011
An unusual cause of acute confusional state. Indian pediatrics, 2012, Volume: 49, Issue:1 Topics: Amphetamine; Child, Preschool; Confusion; Female; Humans; Poisoning	2012
Dexedrine poisoning in an infant. The West Virginia medical journal, 1953, Volume: 49, Issue:7 Topics: Amphetamine; Dextroamphetamine; Humans; Infant; Poisoning	1953
[Dexedrine poisoning; two cases, one fatal]. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1953, Oct-24, Volume: 27, Issue:43 Topics: Amphetamine; Dextroamphetamine; Humans; Poisoning	1953
[Therapy and clinical aspects of acute barbituric acid intoxications]. Medizinische Klinik, 1954, Dec-17, Volume: 49, Issue:51 Topics: Amphetamine; Amphetamines; Barbiturates; Drug-Related Side Effects and Adverse Reactions; Humans; Po	1954
Acute dexedrine intoxication in children. Archives of pediatrics, 1955, Volume: 72, Issue:4 Topics: Amphetamine; Central Nervous System Agents; Child; Dextroamphetamine; Drug-Related Side Effects and	1955
FATAL AMPHETAMINE POISONING. Archives of internal medicine, 1963, Volume: 112 Topics: Amphetamine; Amphetamines; Kidney; Kidneys, Artificial; Methamphetamine; Pathology; Poisoning; Suici	1963
THE PLACE OF ACETYLSALICYLIC ACID IN PSYCHOPHARMACOLOGY. AN EXPERIMENTAL STUDY. Arzneimittel-Forschung, 1963, Volume: 13 Topics: Amphetamine; Amphetamines; Animals; Aspirin; Body Temperature Regulation; Chlordiazepoxide; Chlorpro	1963
TWO SUICIDE ATTEMPTS WITH CHLORPROMAZINE. The American journal of psychiatry, 1965, Volume: 121 Topics: Amphetamine; Chlorpromazine; Coma; Depression; Dextroamphetamine; Drug Therapy; Gastric Lavage; Hypo	1965
ACUTE LETHALITY OF THE AMPHETAMINES IN DOGS AND ITS ANTAGONISM BY CURARE. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118 Topics: Amphetamine; Amphetamines; Antidotes; Curare; Dextroamphetamine; Dogs; Methamphetamine; Poisoning; R	1965
[Acute amphetamine poisoning]. Il Farmaco; edizione pratica, 1955, Volume: 10, Issue:1 Topics: Amphetamine; Central Nervous System Agents; Humans; Poisoning	1955
Acute barbiturate intoxication treated by massive amphetamine therapy. New York state journal of medicine, 1951, Aug-01, Volume: 51, Issue:15 Topics: Amphetamine; Amphetamines; Barbital; Barbiturates; Poisoning; Poisons; Psychoses, Substance-Induced	1951
[Use of central analeptics in acute hypnotic poisoning]. Ugeskrift for laeger, 1950, May-11, Volume: 112, Issue:19 Topics: Amphetamine; Amphetamines; Barbital; Central Nervous System Stimulants; Hypnotics and Sedatives; Poi	1950
Poisoning or primary nervous system disease?--difficulties of the differential diagnosis exemplified by four different clinical cases. Przeglad lekarski, 2005, Volume: 62, Issue:6 Topics: Acute Disease; Adolescent; Adult; Amphetamine; Antipsychotic Agents; Central Nervous System Stimulan	2005
[Diagnostics and interpretation of results in forensic toxicology of amphetamines]. Annales Academiae Medicae Stetinensis, 2006, Volume: 52, Issue:3 Topics: Amphetamine; Amphetamine-Related Disorders; Amphetamines; Body Fluids; Brain Chemistry; Chromatograp	2006
Lethal intoxications with centrally stimulating amines in Sweden 1966-1973. Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1975, Volume: 75, Issue:4 Topics: Accidents; Accidents, Traffic; Adolescent; Adult; Amphetamine; Autopsy; Female; Humans; Male; Middle	1975
[Alkylans-alkylandum reactions. 8. Therapeutic effect of some cerebral serotonin liberators in nitrogen mustard intoxication of the mouse]. Arzneimittel-Forschung, 1972, Volume: 22, Issue:9 Topics: Adrenergic Agents; Amphetamine; Animals; Antidotes; Chlorine; Fenclonine; Male; Mechlorethamine; Mic	1972
Drug abuse and the emergency room physician. The American journal of psychiatry, 1974, Volume: 131, Issue:5 Topics: Alcoholism; Amphetamine; Antipsychotic Agents; Attitude of Health Personnel; Coma; Emergency Service	1974
Letter: Amphetamine death? JAMA, 1974, Mar-18, Volume: 227, Issue:11 Topics: Amphetamine; Autopsy; Humans; Poisoning; Substance-Related Disorders	1974
Chromatography and forensic chemistry. Journal of chromatographic science, 1974, Volume: 12, Issue:10 Topics: Amphetamine; Barbiturates; Cannabis; Carbon Monoxide Poisoning; Chromatography; Chromatography, Gas;	1974
Treatment of acute hallucinogenic drug toxicity: specific pharmacological intervention. American journal of hospital pharmacy, 1973, Volume: 30, Issue:1 Topics: Amphetamine; Atropa belladonna; Chlorpromazine; Dronabinol; Hallucinogens; Humans; Lysergic Acid Die	1973
Emergency room treatment of the drug-abusing patient. The American journal of psychiatry, 1973, Volume: 130, Issue:3 Topics: Amphetamine; Atropa belladonna; Barbiturates; Cannabis; Cocaine; Emergency Service, Hospital; Halluc	1973
[Amphetamine poisoning]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Jan-10, Volume: 93, Issue:1 Topics: Amphetamine; Humans; Poisoning; Substance-Related Disorders	1973
Unexpected ethanol in drug-intoxicated persons. Postgraduate medicine, 1973, Volume: 54, Issue:2 Topics: Alcoholic Intoxication; Amphetamine; Barbiturates; Diagnosis, Differential; Emergency Service, Hospi	1973
Clinical toxicology. VII. Poisoning by salicylates, paracetamol, tricyclic antidepressants and a miscellany of drugs. The Practitioner, 1973, Volume: 211, Issue:261 Topics: Acetaminophen; Adult; Amphetamine; Antidepressive Agents; Caustics; Digitalis; Fenfluramine; Humans;	1973
Acute drug poisoning in the adult. Canadian Medical Association journal, 1973, Oct-06, Volume: 109, Issue:7 Topics: Adult; Amphetamine; Antidepressive Agents; Cocaine; Diazepam; Diphenhydramine; Diuresis; Emergency S	1973
Chemical evaluation of 'drug cocktails' in autopsy specimens. Journal of chromatographic science, 1974, Volume: 12, Issue:5 Topics: Adult; Amphetamine; Autopsy; Barbiturates; Body Fluids; Forensic Medicine; Hallucinogens; Humans; Hy	1974
PMA deaths in Ontario. Canadian Medical Association journal, 1974, Jun-08, Volume: 110, Issue:11 Topics: Adolescent; Adult; Amphetamine; Animals; Behavior, Animal; Hallucinogens; Humans; Male; Methyl Ether	1974
Drug control and the British Health Service. Annals of internal medicine, 1969, Volume: 71, Issue:2 Topics: Amphetamine; Barbiturates; Community Health Services; Drug and Narcotic Control; Drug Prescriptions;	1969
[Amphetamine poisoning]. Lakartidningen, 1972, Sep-20, Volume: 69, Issue:39 Topics: Adolescent; Adult; Amphetamine; Blood Pressure; Depression; Euphoria; Female; Humans; Male; Mental D	1972
Amphetamine intoxication with coagulopathy, hyperthermia, and reversible renal failure. A syndrome resembling heatstroke. Annals of internal medicine, 1970, Volume: 73, Issue:1 Topics: Acute Kidney Injury; Adult; Amphetamine; Diagnosis, Differential; Fever; Fibrinolysis; Heat Exhausti	1970
Drugs and reality in captive society. Some observations on chemical adaptation. Canadian Psychiatric Association journal, 1970, Volume: 15, Issue:2 Topics: Adult; Amphetamine; Blindness; Carbon Tetrachloride; Cosmetics; Ethanol; Ethics, Medical; Female; Hu	1970
The use and abuse of psychotropic drugs. General aspects. Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:12 Topics: Amphetamine; Barbiturates; Drug Prescriptions; Humans; Hypnotics and Sedatives; Lysergic Acid Diethy	1970
Poisoning in children--a statistical study of 1,057 cases. The Journal of pediatrics, 1971, Volume: 78, Issue:2 Topics: Age Factors; Amphetamine; Arsenic Poisoning; Aspirin; Barbiturates; Child; Child, Preschool; Female;	1971
Acute toxic effects of drug abuse: diagnosis and treatment. The Journal of the Florida Medical Association, 1971, Volume: 58, Issue:4 Topics: Amphetamine; Barbiturates; Hallucinogens; Humans; Narcotics; Poisoning; Substance Withdrawal Syndrom	1971
Trends in accidental poisoning in childhood. Los Angeles County experience. Clinical pediatrics, 1971, Volume: 10, Issue:3 Topics: Accident Prevention; Accidents; Amphetamine; California; Child; Child, Preschool; Deodorants; Family	1971
Laboratory investigation of common sedatives and stimulants. Canadian journal of medical technology, 1971, Volume: 33, Issue:1 Topics: Amphetamine; Barbiturates; Chromatography, Thin Layer; Hallucinogens; Humans; Phenothiazines; Poison	1971
[Treatment of acute poisoning. 2. Views on toxicological and chemical diagnosis]. Lakartidningen, 1971, Mar-29, Volume: 68 Topics: Acute Disease; Adolescent; Amphetamine; Autopsy; Chromatography, Gas; Chromatography, Paper; Female;	1971
[Treatment of acute poisoning. 3. Pharmacokinetic treatment principals]. Lakartidningen, 1971, Mar-29, Volume: 68 Topics: Acute Disease; Amphetamine; Aspirin; Barbiturates; Dialysis; Diuresis; Gastric Lavage; Half-Life; Hu	1971

amphetamine and Poisoning

Research Excerpts

Research

Studies (49)

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