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amphetamine and Pheochromocytoma

amphetamine has been researched along with Pheochromocytoma in 4 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"Tranylcypromine, a useful antidepressant agent, has been linked with a clinical syndrome of undetermined incidence characterized by exceedingly severe and prolonged headache."3.64TRANYLCYPROMINE CEPHALGIA. ( LAING, WA; MANN, AM, 1963)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BLACKWELL, B1
MANN, AM1
LAING, WA1
Kantor, L1
Hewlett, GH1
Park, YH1
Richardson-Burns, SM1
Mellon, MJ1
Gnegy, ME1
Horwitz, D1
Alexander, RW1
Lovenberg, W1
Keiser, HR1

Other Studies

4 other studies available for amphetamine and Pheochromocytoma

ArticleYear
HYPERTENSIVE CRISIS DUE TO MONOAMINE-OXIDASE INHIBITORS.
    Lancet (London, England), 1963, Oct-26, Volume: 2, Issue:7313

    Topics: Amphetamine; Amphetamines; Cheese; Diagnosis, Differential; Dietary Proteins; Headache; Hypertension

1963
TRANYLCYPROMINE CEPHALGIA.
    Canadian Medical Association journal, 1963, Nov-30, Volume: 89

    Topics: Amphetamine; Antidepressive Agents; Diagnosis, Differential; Headache; Humans; Hypertension; Norepin

1963
Protein kinase C and intracellular calcium are required for amphetamine-mediated dopamine release via the norepinephrine transporter in undifferentiated PC12 cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Amphetamine; Animals; Biological Transport; Calcium; Carrier Proteins; Cell Differentiation; Dopamin

2001
Human serum dopamine- -hydroxylase. Relationship to hypertension and sympathetic activity.
    Circulation research, 1973, Volume: 32, Issue:5

    Topics: Adrenal Gland Neoplasms; Adult; Amphetamine; Blood Flow Velocity; Blood Pressure; Dopamine beta-Hydr

1973