Page last updated: 2024-10-25

amphetamine and Neurodegenerative Diseases

amphetamine has been researched along with Neurodegenerative Diseases in 6 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leino, S1
Koski, SK1
Hänninen, R1
Tapanainen, T1
Rannanpää, S1
Salminen, O1
Butler, B1
Saha, K1
Rana, T1
Becker, JP1
Sambo, D1
Davari, P1
Goodwin, JS1
Khoshbouei, H1
Vomund, S1
de Souza Silva, MA1
Huston, JP1
Korth, C1
Decressac, M2
Ulusoy, A1
Mattsson, B2
Georgievska, B1
Romero-Ramos, M1
Kirik, D1
Björklund, A2
Lundblad, M1
Weikop, P1
Bowyer, JF1
Harris, AJ1
Delongchamp, RR1
Jakab, RL1
Miller, DB1
Little, AR1
O'Callaghan, JP1

Other Studies

6 other studies available for amphetamine and Neurodegenerative Diseases

ArticleYear
Attenuated dopaminergic neurodegeneration and motor dysfunction in hemiparkinsonian mice lacking the α5 nicotinic acetylcholine receptor subunit.
    Neuropharmacology, 2018, Volume: 138

    Topics: Amphetamine; Animals; Antiparkinson Agents; Brain; Central Nervous System Stimulants; Dopamine; Dopa

2018
Dopamine Transporter Activity Is Modulated by α-Synuclein.
    The Journal of biological chemistry, 2015, Dec-04, Volume: 290, Issue:49

    Topics: alpha-Synuclein; Amphetamine; Animals; Biotinylation; Brain; Cell Line; Cell Membrane; CHO Cells; Cr

2015
Behavioral Resilience and Sensitivity to Locally Restricted Cortical Migration Deficits Induced by In Utero Knockdown of Disabled-1 in the Adult Rat.
    Cerebral cortex (New York, N.Y. : 1991), 2017, 03-01, Volume: 27, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Amphetamine; Animals; Cell Line, Tumor; Cell Movement; Central

2017
GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease.
    Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 8

    Topics: Amphetamine; Animals; Animals, Genetically Modified; Cell Count; Corpus Striatum; Disease Models, An

2011
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
    Neurobiology of disease, 2012, Volume: 45, Issue:3

    Topics: alpha-Synuclein; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Behavioral Sympto

2012
Selective changes in gene expression in cortical regions sensitive to amphetamine during the neurodegenerative process.
    Neurotoxicology, 2004, Volume: 25, Issue:4

    Topics: Amphetamine; Animals; Cerebral Cortex; Dopamine; Gene Expression Regulation; Male; Neurodegenerative

2004