amphetamine has been researched along with Nervous System Diseases in 15 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A benzodiazepine (oxazepam) was given to nulliparous mice on days 12-16 of pregnancy, and the development and young adult behaviour of the offspring were studied." | 3.67 | Short-, medium-, and long-term effects of prenatal oxazepam on neurobehavioural development of mice. ( Alleva, E; Bignami, G; Laviola, G; Tirelli, E, 1985) |
| " Dose-response curves for the effects of PPA and amphetamine (administered IP, 15 min presession) were then determined (ED50 = 35." | 1.28 | Evaluation of the pharmacological similarities between phenylpropanolamine and amphetamine: effects on schedule-controlled behavior. ( Jarvis, MF; Wagner, GC, 1990) |
| "The present studies were undertaken to examine 1) whether d-amphetamine sulfate administered to rats well after thrombotic infarction of the vibrissal cortical barrel-field within the primary somatosensory cortex affected the rate and completeness of behavioral recovery and 2) whether a dose-response relation exists between d-amphetamine sulfate dose and recovery of function." | 1.28 | Amphetamine promotes recovery from sensory-motor integration deficit after thrombotic infarction of the primary somatosensory rat cortex. ( Alonso, O; Dietrich, WD; Ginsberg, MD; Hurwitz, BE; McCabe, PM; Schneiderman, N; Watson, BD, 1991) |
| "In classical migraine (headache associated with prodromal visual field disturbances) and migraine accompagnée (headache associated with transient neurological symptoms), disturbances of cerebral blood flow and amine metabolism are thought to be pathogenetic factors." | 1.27 | 123I-amphetamine-SPECT in classical migraine and migraine accompagnée. ( Böttger, I; Brune, G; Grotemeyer, KH; Husstedt, IW; Schlake, HP, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansen, C | 1 |
| Björklund, T | 1 |
| Petit, GH | 1 |
| Lundblad, M | 1 |
| Murmu, RP | 1 |
| Brundin, P | 1 |
| Li, JY | 1 |
| Chao, OY | 1 |
| Pum, ME | 1 |
| Li, JS | 1 |
| Huston, JP | 1 |
| MAKAROV, AIu | 1 |
| von Kerékjártó, M | 1 |
| Wray, SR | 1 |
| Melville, GN | 1 |
| Grell, GA | 1 |
| Edge, PC | 1 |
| Del Zompo, M | 1 |
| Piccardi, MP | 1 |
| Ruiu, S | 1 |
| Quartu, M | 1 |
| Gessa, GL | 1 |
| Vaccari, A | 1 |
| Tripathi, M | 1 |
| Verma, M | 1 |
| Palit, G | 3 |
| Shanker, K | 3 |
| Singh, V | 2 |
| Srivastava, VK | 2 |
| Fuller, RW | 1 |
| Hemrick-Luecke, SK | 1 |
| Ornstein, PL | 1 |
| Khanna, R | 1 |
| Wagner, GC | 1 |
| Jarvis, MF | 1 |
| Hurwitz, BE | 1 |
| Dietrich, WD | 1 |
| McCabe, PM | 1 |
| Alonso, O | 1 |
| Watson, BD | 1 |
| Ginsberg, MD | 1 |
| Schneiderman, N | 1 |
| Schlake, HP | 1 |
| Grotemeyer, KH | 1 |
| Böttger, I | 1 |
| Husstedt, IW | 1 |
| Brune, G | 1 |
| Alleva, E | 1 |
| Laviola, G | 1 |
| Tirelli, E | 1 |
| Bignami, G | 1 |
| Schwartz, JF | 1 |
2 reviews available for amphetamine and Nervous System Diseases
| Article | Year |
|---|---|
Current concepts of abnormal motor disorder: an experimental model of attentional deficit disorder.
Topics: Amphetamine; Animals; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Avoidance | 1981 |
Drug-induced neurologic disorders in childhood.
Topics: Adolescent; Adult; Age Factors; Aged; Amphetamine; Anesthesia, Inhalation; Anesthesia, Local; Animal | 1971 |
1 trial available for amphetamine and Nervous System Diseases
| Article | Year |
|---|---|
[Differences between prophylactic and therapeutic effects of stimulant drugs].
Topics: Adult; Amphetamine; Antidepressive Agents; Humans; Male; Methylphenidate; Nervous System Diseases; P | 1966 |
12 other studies available for amphetamine and Nervous System Diseases
| Article | Year |
|---|---|
A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.
Topics: Aging; alpha-Synuclein; Amphetamine; Animals; Discrimination, Psychological; Dopamine; Dopamine Agen | 2013 |
The grid-walking test: assessment of sensorimotor deficits after moderate or severe dopamine depletion by 6-hydroxydopamine lesions in the dorsal striatum and medial forebrain bundle.
Topics: Amphetamine; Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Up | 2012 |
[Clinical application in nervous system diseases of a new stimulator of the nervous system phenatine].
Topics: Amphetamine; Amphetamines; Central Nervous System Depressants; Nervous System Diseases; Niacin; Nico | 1958 |
Selective MPP+ uptake into synaptic dopamine vesicles: possible involvement in MPTP neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Biomarkers; Brain; Corpus Striat | 1993 |
Antipyrine congeners as antidepressant agents.
Topics: Amphetamine; Animals; Antidepressive Agents; Antipyrine; Behavior, Animal; Female; Imipramine; Letha | 1993 |
Coumarin congeners as antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Coumarins; Drug Synergism; Female; Le | 1992 |
Protection against amphetamine-induced neurotoxicity toward striatal dopamine neurons in rodents by LY274614, an excitatory amino acid antagonist.
Topics: Amino Acids; Amphetamine; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dose-Response Rel | 1992 |
Synthesis and pharmacological evaluation of some phenothiazines as antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents; Depression; Drug Synergism; Female; Male; Mice; Nervous | 1992 |
Evaluation of the pharmacological similarities between phenylpropanolamine and amphetamine: effects on schedule-controlled behavior.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Conditioning, Operant; Male; Methyltyrosines; Nervous Sy | 1990 |
Amphetamine promotes recovery from sensory-motor integration deficit after thrombotic infarction of the primary somatosensory rat cortex.
Topics: Amphetamine; Animals; Cerebral Infarction; Learning; Male; Motor Activity; Nervous System Diseases; | 1991 |
123I-amphetamine-SPECT in classical migraine and migraine accompagnée.
Topics: Adolescent; Adult; Amphetamine; Basilar Artery; Cerebrovascular Disorders; Female; Hemiplegia; Human | 1987 |
Short-, medium-, and long-term effects of prenatal oxazepam on neurobehavioural development of mice.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Female; Growth Disorders; Learning Disab | 1985 |