amphetamine has been researched along with Movement Disorders in 60 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
Excerpt | Relevance | Reference |
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" Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke." | 8.85 | Speeding stroke recovery? A systematic review of amphetamine after stroke. ( Bath, PM; Sprigg, N, 2009) |
" Clinical evidence suggests that a similar agonist-induced hypersensitivity may play a role in the development of dyskinetic movement disorders and psychoses in humans following the chronic use of such dopamine agonists as amphetamine and levodopa." | 7.65 | Amphetamine-induced dopaminergic hypersensitivity in guinea pigs. Implications in psychosis and human movement disorders. ( Klawans, HL; Margolin, DI, 1975) |
" Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke." | 4.85 | Speeding stroke recovery? A systematic review of amphetamine after stroke. ( Bath, PM; Sprigg, N, 2009) |
"Excepting clozapine and DOD 647, all drugs induced dystonia." | 3.70 | New and old antipsychotics versus clozapine in a monkey model: adverse effects and antiamphetamine effects. ( Gerlach, J; Peacock, L, 1999) |
"We report two case histories of previously healthy patients who both developed persistent dyskinetic syndromes (spasmodic torticollis and cranial dystonia, respectively) following the intake of norpseudoephedrine (NPE) as an appetite suppressant." | 3.69 | Dyskinesias possibly induced by norpseudoephedrine. ( Dressler, D; Thiel, A, 1994) |
" Clinical evidence suggests that a similar agonist-induced hypersensitivity may play a role in the development of dyskinetic movement disorders and psychoses in humans following the chronic use of such dopamine agonists as amphetamine and levodopa." | 3.65 | Amphetamine-induced dopaminergic hypersensitivity in guinea pigs. Implications in psychosis and human movement disorders. ( Klawans, HL; Margolin, DI, 1975) |
" Tremors induced by chemical agents (nicotine, zinc and tremorine) were markedly inhibited by HA-966." | 3.65 | 1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA-like compound, with potential use in extrapyramidal diseases. ( Bonta, IL; De Vos, CJ; Grijsen, H; Hillen, FC; Noach, EL; Sim, AW, 1971) |
"Rats with ablated frontal sensorimotor cortex and one with ablated sensorimotor connections to forebrain showed more vacuous chewing movements following 6-week chronic administration of a neuroleptic than did occipitally damaged rats or normal controls who were treated in the same way." | 1.26 | Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia. ( Glassman, HN; Glassman, RB, 1980) |
" Although directly related to daily dosage of levodopa, the myoclonus was specifically blocked by the serotonin antagonist, methysergide." | 1.25 | Levodopa-induced myoclonus. ( Bergen, D; Goetz, C; Klawans, HL, 1975) |
" Prolonged pretreatment with suprathreshold doses of amphetamine decreased the threshold dosage of both amphetamine and apomorphine necessary to elicit stereotyped behavior." | 1.25 | Effect of chronic amphetamine exposure on stereotyped behavior: implications for pathogenesis of l-dopa-induced dyskinesias. ( Crossett, P; Dana, N; Klawans, HL, 1975) |
"Reserpine pretreatment potentiates turning produced by (-)-ephedrine." | 1.25 | Turning behaviour as an index of the action of amphetamines and ephedrines on central dopamine-containing neurones. ( Christie, JE; Crow, TJ, 1971) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 53 (88.33) | 18.7374 |
1990's | 3 (5.00) | 18.2507 |
2000's | 3 (5.00) | 29.6817 |
2010's | 1 (1.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Hansen, C | 1 |
Björklund, T | 1 |
Petit, GH | 1 |
Lundblad, M | 1 |
Murmu, RP | 1 |
Brundin, P | 2 |
Li, JY | 1 |
Sprigg, N | 1 |
Bath, PM | 1 |
LOMAN, J | 1 |
ARRIGONI-MARTELLI, E | 2 |
BISIANI, M | 1 |
GENOVESE, E | 2 |
GOLDWURM, GF | 1 |
ZRULL, JP | 1 |
WESTMAN, JC | 1 |
ARTHUR, B | 1 |
BELL, WA | 1 |
MCCONNELL, TR | 1 |
CROMWELL, RL | 1 |
BURKS, HF | 1 |
Corad, WG | 1 |
Insel, J | 1 |
Ney, PG | 1 |
Glassman, RB | 1 |
Glassman, HN | 1 |
Wray, SR | 1 |
Melville, GN | 1 |
Grell, GA | 1 |
Edge, PC | 1 |
Thiel, A | 1 |
Dressler, D | 1 |
Löscher, W | 1 |
Richter, A | 1 |
Nikkhah, G | 1 |
Rosenthal, C | 1 |
Ebert, U | 1 |
Hedrich, HJ | 1 |
Peacock, L | 1 |
Gerlach, J | 1 |
Campbell, JM | 1 |
Gilmore, DP | 1 |
Russell, D | 1 |
Growney, CA | 1 |
Favor, G | 1 |
Kennedy, AK | 1 |
Davies, RW | 1 |
Payne, AP | 1 |
Stone, TW | 1 |
Crocker, SJ | 1 |
Wigle, N | 1 |
Liston, P | 1 |
Thompson, CS | 1 |
Lee, CJ | 1 |
Xu, D | 1 |
Roy, S | 1 |
Nicholson, DW | 1 |
Park, DS | 1 |
MacKenzie, A | 1 |
Korneluk, RG | 1 |
Robertson, GS | 1 |
Klawans, HL | 9 |
Weiner, WJ | 3 |
Wolgin, DL | 1 |
Teitelbaum, P | 1 |
Barry, VC | 1 |
Cerbo, R | 2 |
Carchedi, F | 1 |
Casacchia, M | 1 |
Agnoli, A | 2 |
Goetz, C | 1 |
Bergen, D | 1 |
Silva, MT | 1 |
Calil, HM | 1 |
Sassin, JF | 1 |
Margolin, DI | 1 |
Wilimowski, M | 1 |
Witkowska, M | 1 |
Barczyńska, J | 1 |
Kedzierska, L | 1 |
Orzechowska-Juzwenko, K | 1 |
Wojewódzki, W | 1 |
Felsztyńska, J | 1 |
Crossett, P | 1 |
Dana, N | 1 |
Meco, G | 1 |
Ruggieri, S | 1 |
Carolei, A | 1 |
Zamponi, A | 1 |
Sudilovsky, A | 1 |
Isacson, O | 1 |
Gage, FH | 1 |
Prochiantz, A | 1 |
Björklund, A | 1 |
Mintz, M | 1 |
Douglas, RJ | 1 |
Tomer, R | 1 |
de Villiers, AS | 1 |
Kellaway, L | 1 |
Glick, SD | 1 |
Poirier, LJ | 1 |
Langelier, P | 1 |
Bédard, P | 1 |
Boucher, R | 1 |
Larochelle, L | 1 |
Parent, A | 1 |
Roberge, AG | 1 |
Birkmayer, W | 1 |
Ungerstedt, U | 1 |
Divac, I | 1 |
Millichap, JG | 2 |
Boldrey, EE | 1 |
Aceto, MD | 1 |
Harris, LS | 1 |
Lesher, GY | 1 |
Pearl, J | 1 |
Brown, TG | 1 |
McKenzie, GM | 1 |
Gordon, RJ | 1 |
Viik, K | 1 |
Calne, DB | 1 |
Reid, JL | 1 |
Wender, PH | 1 |
Rubovits, R | 3 |
Patel, BC | 1 |
Strian, F | 1 |
Alexandris, A | 1 |
Lundell, FW | 1 |
Fowler, GW | 1 |
North, RR | 1 |
Bonta, IL | 1 |
De Vos, CJ | 1 |
Grijsen, H | 1 |
Hillen, FC | 1 |
Noach, EL | 1 |
Sim, AW | 1 |
Christie, JE | 1 |
Crow, TJ | 1 |
Meyers, KM | 1 |
Dickson, WM | 1 |
Lund, JE | 1 |
Padgett, GA | 1 |
Umbach, W | 1 |
Florio, V | 1 |
Lipparini, F | 1 |
Scotti de Carolis, A | 1 |
Longo, VG | 1 |
Galambos, E | 1 |
Pfeifer, AK | 1 |
György, L | 1 |
Molnár, J | 1 |
Levy, S | 2 |
Schneider, C | 1 |
Eveloff, HH | 1 |
Kriskó, I | 1 |
Lewis, E | 1 |
Johnson, JE | 1 |
8 reviews available for amphetamine and Movement Disorders
Article | Year |
---|---|
Speeding stroke recovery? A systematic review of amphetamine after stroke.
Topics: Amphetamine; Blood Pressure; Heart Rate; Humans; Movement Disorders; Stroke; Treatment Outcome | 2009 |
Current concepts of abnormal motor disorder: an experimental model of attentional deficit disorder.
Topics: Amphetamine; Animals; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Avoidance | 1981 |
The pharmacology of choreatic movement disorders.
Topics: Acetylcholine; Acute Disease; Amphetamine; Chorea; Dopamine; gamma-Aminobutyric Acid; Hepatolenticul | 1976 |
On the role of dopamine in the pathophysiology of anorexia nervosa.
Topics: 17-Ketosteroids; Amphetamine; Anorexia Nervosa; Apomorphine; Compulsive Personality Disorder; Dopami | 1976 |
Drug-induced dyskinesia in monkeys.
Topics: Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Azides; Carbachol; Caudate Nucle | 1975 |
Antiparkinsonian drugs: pharmacological and therapeutic aspects.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Amantadine; Amphetamine; Antiparkinson Agents; Apomorphi | 1972 |
Minimal brain dysfunction in children. Diagnosis and management.
Topics: Abnormalities, Multiple; Affective Symptoms; Age Factors; Amphetamine; Attention; Attention Deficit | 1973 |
Treatment of "minimal brain dysfunction" syndromes. Selection of drugs for children with hyperactivity and learning disabilities.
Topics: Amphetamine; Anticonvulsants; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Clinic | 1967 |
4 trials available for amphetamine and Movement Disorders
Article | Year |
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[10 years of L-DOPA therapy of Parkinson's syndrome].
Topics: Administration, Oral; Amphetamine; Animals; Brain Chemistry; Catecholamines; Clinical Trials as Topi | 1971 |
Studies in hyperkinetic behavior. II. Laboratory and clinical evaluations of drug treatments.
Topics: Adolescent; Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Child; Higher | 1967 |
Effect of thioridazine, amphetamine and placebo on the hyperkinetic syndrome and cognitive area in mentally deficient children.
Topics: Aggression; Amphetamine; Attention; Child; Child Behavior Disorders; Clinical Trials as Topic; Human | 1968 |
Treatment of "minimal brain dysfunction" syndromes. Selection of drugs for children with hyperactivity and learning disabilities.
Topics: Amphetamine; Anticonvulsants; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Clinic | 1967 |
49 other studies available for amphetamine and Movement Disorders
Article | Year |
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A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.
Topics: Aging; alpha-Synuclein; Amphetamine; Animals; Discrimination, Psychological; Dopamine; Dopamine Agen | 2013 |
The effect of amphetamine sulfate on spasmodic flexion movements of the foot; report of a case.
Topics: Amphetamine; Amphetamines; Foot; Humans; Movement Disorders; Spasm | 1947 |
[Effect of phenothiazine derivatives on increased motility of the mouse].
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Chlorpromazine; Methylphenidate; Mice; Mov | 1958 |
[Effects of iproniazid on increased spontaneous motility due to central stimulants].
Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Iproniazid; Methylphenidate; Movement | 1958 |
A COMPARISON OF CHLORDIAZEPOXIDE, D-AMPHETAMINE, AND PLACEBO IN THE TREATMENT OF THE HYPERKINETIC SYNDROME IN CHILDREN.
Topics: Amphetamine; Amphetamines; Attention Deficit Disorder with Hyperactivity; Child; Chlordiazepoxide; D | 1963 |
STUDIES IN ACTIVITY LEVEL. VII. EFFECTS OF AMPHETAMINE DRUG ADMINISTRATION ON THE ACTIVITY LEVEL OF RETARDED CHILDREN.
Topics: Adolescent; Amphetamine; Amphetamines; Child; Humans; Intellectual Disability; Movement Disorders; P | 1964 |
EFFECTS OF AMPHETAMINE THERAPY ON HYPERKINETIC CHILDREN.
Topics: Amphetamine; Amphetamines; Behavior; Child; Drug Therapy; Electroencephalography; Humans; Movement D | 1964 |
Anticipating the response to amphetamine therapy in the treatment of hyperkinetic children.
Topics: Amphetamine; Child; Child, Preschool; Emotions; Female; Humans; Male; Movement Disorders; Parent-Chi | 1967 |
Psychosis in a child, associated with amphetamine administration.
Topics: Amphetamine; Brain Damage, Chronic; Child; Hallucinations; Humans; Male; Movement Disorders; Psychos | 1967 |
Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Di | 1980 |
Dyskinesias possibly induced by norpseudoephedrine.
Topics: Adult; Amphetamine; Appetite Depressants; Brain; Female; Humans; Magnetic Resonance Imaging; Methylp | 1994 |
Behavioral and neurochemical dysfunction in the circling (ci) rat: a novel genetic animal model of a movement disorder.
Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain Chemistry; Central | 1996 |
New and old antipsychotics versus clozapine in a monkey model: adverse effects and antiamphetamine effects.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cebus; Clozapine; Dextroamphetamine; Disease Models, Ani | 1999 |
Pharmacological analysis of extracellular dopamine and metabolites in the striatum of conscious as/agu rats, mutants with locomotor disorder.
Topics: Amphetamine; Animals; Clorgyline; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Uptake Inhibi | 2000 |
NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease.
Topics: Amphetamine; Amyloid beta-Protein Precursor; Animals; Antibodies; Caspase 3; Caspases; Cell Survival | 2001 |
Role of activation and sensory stimuli in recovery from lateral hypothalamic damage in the cat.
Topics: Aggression; Amphetamine; Animals; Arousal; Behavior, Animal; Cats; Drinking Behavior; Feeding Behavi | 1978 |
[Role of serotonin in involuntary movements induced with amphetamine].
Topics: Amphetamine; Animals; Brain; Male; Movement Disorders; Rats; Serotonin; Serotonin Antagonists | 1976 |
Levodopa-induced myoclonus.
Topics: 5-Hydroxytryptophan; Aged; Amantadine; Amphetamine; Animals; Benztropine; Dopamine Antagonists; Dose | 1975 |
Screening hallucinogenic drugs: systematic study of three behavioral tests.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Arousal; Behavior, Animal; Chlorpromazine; D | 1975 |
Amphetamine-induced dopaminergic hypersensitivity in guinea pigs. Implications in psychosis and human movement disorders.
Topics: Amphetamine; Animals; Apomorphine; Behavior; Behavior, Animal; Disease Models, Animal; Dopamine Anta | 1975 |
Central action of 2-amino- and 2-amino-5-aryltetrahydropyrimidinediones-4,6.
Topics: Amphetamine; Analgesia; Animals; Central Nervous System; Dihydroxyphenylalanine; Drug Synergism; Fem | 1975 |
Effect of chronic amphetamine exposure on stereotyped behavior: implications for pathogenesis of l-dopa-induced dyskinesias.
Topics: Amphetamine; Animals; Apomorphine; Behavior; Corpus Striatum; Dextroamphetamine; Guinea Pigs; Humans | 1975 |
[Animal stereotypy and transmethylation of cerebral amines].
Topics: Amines; Amphetamine; Animals; Apomorphine; Brain; Levodopa; Movement Disorders; Piribedil; Rats; S-A | 1975 |
Disruption of behavior in cats by chronic amphetamine intoxication.
Topics: Amphetamine; Animals; Behavior; Cats; Chronic Disease; Humans; Movement Disorders; Stereotyped Behav | 1975 |
The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting.
Topics: Amphetamine; Animals; Basal Ganglia Diseases; Corpus Striatum; Disease Models, Animal; Dopamine; Hyd | 1986 |
Transient contralateral rotation following unilateral substantia nigra lesion reflects susceptibility of the nigrostriatal system to exhaustion by amphetamine.
Topics: Amphetamine; Animals; Corpus Striatum; Desipramine; Dominance, Cerebral; Drug Tolerance; Hydroxydopa | 1986 |
Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Changes in drug sensitivity during recovery of function after brain damage.
Topics: Amphetamine; Animals; Apomorphine; Brain; Brain Injuries; Brain Mapping; Corpus Striatum; Frontal Lo | 1974 |
Dopaminergic and cholinergic mechanisms in relation to postural tremor in the monkey and circling movements in the cat.
Topics: Acetylcholine; Amphetamine; Animals; Cats; Corpus Striatum; Disease Models, Animal; Dopamine; Fronta | 1974 |
Lingual-facial-buccal movements in the elderly. I. Pathophysiology and treatment.
Topics: Aged; Amphetamine; Chemoreceptor Cells; Chlorpromazine; Corpus Striatum; Dopamine Antagonists; Facia | 1973 |
Striatal dopamine release after amphetamine or nerve degeneration revealed by rotational behaviour.
Topics: Amphetamine; Animals; Apomorphine; Brain; Butyrophenones; Dopamine; Electrocoagulation; Haloperidol; | 1971 |
Drug-induced syndromes in rats with large, chronic lesions in the corpus striatum.
Topics: Amphetamine; Animals; Apomorphine; Basal Ganglia; Behavior, Animal; Brain; Globus Pallidus; Haloperi | 1972 |
Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid.
Topics: Amphetamine; Animals; Catecholamines; Chlorine; Depression; Drug Antagonism; Drug Synergism; Humans; | 1967 |
Some biochemical and behavioural correlates of a possible animal model of human hyperkinetic syndromes.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Catecholamines; Cats; Caudate Nucleus; Chlorpromaz | 1972 |
Cholinergic and anticholinergic influences on amphetamine-induced stereotyped behavior.
Topics: Amphetamine; Animals; Behavior, Animal; Dopamine; Drug Antagonism; Drug Synergism; Guinea Pigs; Male | 1972 |
An experimental model of tardive dyskinesia.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models | 1972 |
[Psychopathology of encephalitis of the temporal lobe type (author's transl)].
Topics: Adolescent; Adult; Amphetamine; Cognition Disorders; Diagnosis, Differential; Electroencephalography | 1973 |
Implications of amphetamine-induced stereotyped behavior as a model for tardive dyskinesias.
Topics: Amphetamine; Animals; Basal Ganglia; Basal Ganglia Diseases; Brain Chemistry; Caudate Nucleus; Chlor | 1972 |
Drug-induced movement disorders.
Topics: Amphetamine; Contraceptives, Oral; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Hu | 1971 |
1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA-like compound, with potential use in extrapyramidal diseases.
Topics: Acoustic Stimulation; Amines; Amphetamine; Animals; Basal Ganglia Diseases; Behavior, Animal; Brain | 1971 |
Turning behaviour as an index of the action of amphetamines and ephedrines on central dopamine-containing neurones.
Topics: Amphetamine; Animals; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Ephedrine; Explo | 1971 |
Muscular hypertonicity. Episodes in Scottish terrier dogs.
Topics: Amphetamine; Animals; Biopsy; Dog Diseases; Dogs; Electric Stimulation; Electromyography; Movement D | 1971 |
Different effects of drugs before and after stereotaxic operation.
Topics: Amphetamine; Dihydroxyphenylalanine; Globus Pallidus; Humans; Movement Disorders; Parkinson Disease; | 1966 |
EEG and behavioral effects of 2-5-methoxy-4-methyl-amphetamine (DOM, STP).
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Cats; Dextroamphetamine; Electroencephalography; Hall | 1969 |
Study on the excitation induced by amphetamine, cocaine and alpha-methyltryptamine.
Topics: Amphetamine; Animals; Atropine; Benactyzine; Central Nervous System; Chlorpromazine; Cocaine; Mice; | 1967 |
The hyperkinetic child.
Topics: Adolescent; Amphetamine; Child; Child Behavior Disorders; Humans; Motor Activity; Movement Disorders | 1968 |
Behavioural effects of some morphine antagonists and hallucinogens in the rat.
Topics: Amphetamine; Analgesics; Anesthetics; Animals; Ataxia; Atropine; Azocines; Behavior, Animal; Cyclazo | 1968 |
A case of amphetamine-induced dyskinesia.
Topics: Adolescent; Amphetamine; Female; Humans; Movement Disorders | 1968 |
Severe hyperpyrexia due to tranylcypromine-amphetamine toxicity.
Topics: Amphetamine; Coma; Drug Synergism; Female; Fever; Humans; Middle Aged; Movement Disorders; Seizures; | 1969 |
The hyperkinetic child--a forgotten entity, its diagnosis and treatment.
Topics: Adolescent; Adult; Amphetamine; Child; Child Behavior Disorders; Child, Preschool; Electroencephalog | 1966 |