Page last updated: 2024-10-25

amphetamine and Morphine Abuse

amphetamine has been researched along with Morphine Abuse in 63 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"In morphine-pretreated rats, the psychomotor effects of morphine and amphetamine were sensitized."1.31A single exposure to morphine induces long-lasting behavioural and neurochemical sensitization in rats. ( De Vries, TJ; Hogenboom, FA; Schoffelmeer, AN; Vanderschuren, LJ; Wardeh, G, 2001)
"Thrombocytosis was not related to withdrawal symptoms or treatment (phenobarbital or paregoric)."1.26Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users. ( Burstein, Y; Giardina, PJ; Kandall, SR; Peterson, CM; Rausen, AR; Siljestrom, K, 1979)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199057 (90.48)18.7374
1990's2 (3.17)18.2507
2000's3 (4.76)29.6817
2010's1 (1.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elmer, GI1
Pieper, JO1
Hamilton, LR1
Wise, RA1
HILL, HE3
HAERTZEN, CA3
WOLBACH, AB2
MINER, EJ2
BELLEVILLE, RE1
MEYERSTEIN, AN1
WILSON, CW2
McMahon, LR1
Sell, SL1
France, CP1
Martin, WR1
Eades, CG1
Eisenberg, RM2
Schildein, S1
Agmo, A1
Huston, JP1
Schwarting, RK1
Cadoni, C1
Di Chiara, G1
Wang, B1
Luo, F1
Zhang, WT1
Han, JS1
Vanderschuren, LJ1
De Vries, TJ1
Wardeh, G1
Hogenboom, FA1
Schoffelmeer, AN1
Way, EL1
Iwamoto, ET1
Khanna, S1
Ho, IK1
Shen, F1
Loh, HH1
DeFeudis, FV1
Burstein, Y1
Giardina, PJ1
Rausen, AR1
Kandall, SR1
Siljestrom, K1
Peterson, CM1
Bhargava, HN1
Banerjee, U1
Kaa, E1
Matussek, N1
Hauck, G1
Spann, W1
Heller, ME1
Mordkoff, AM1
Bläsig, J2
Papeschi, R1
Herz, A2
Rubin, M1
Müller, U1
Ruppen, R1
Baumann, U1
Angst, J1
Boyd, P1
Ayhan, IH1
Randrup, A1
Gostomzyk, JG1
Westermeyer, J1
Zumbé, FJ1
Beck, KJ1
Schönhöfer, PS1
Jones, BE1
Prada, JA1
Puri, S1
Lal, H2
Tessmann, R1
Abeles, H1
Plew, R1
Laudeutscher, I1
Rosenthal, HM1
Kramer, JP1
Sheppard, CW1
Smith, DE1
Gay, GR1
Robbins, PR1
Trice, HM1
Roman, P1
Cohen, M1
Klein, DF1
Stanton, MD1
Carlini, EA1
Gonzales, C1
Horowitz, RN1
North, R1
Stolerman, IP1
Kumar, R1
Steinberg, H1
James, IP1
Hawks, DV1
Charalampous, KD1
O'Brien, J1
Puri, SK1
Crawley, JA1
Carr, CJ1
Paton, WD1
Kleber, HD1
Baden, MM1
Langrod, J1
Sugar, HS1
Mandell, GH1
Shalev, J1
Lipscomb, WR1
Noble, P1
Barnes, GG1
Bewley, TH1
Hekimian, LJ1
Gershon, S1
Andersson, SJ1
Gunne, LM1
Scher, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Difference in Pharmacodynamic and Pharmacokinetic Profiles Between Tentin and Magisterial Dexamfetamine in Adults With Attention Deficit Hyperactivity Disorder, a Double Blinded Randomised Crossover-controlled Trial[NCT05621174]26 participants (Anticipated)Interventional2023-04-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for amphetamine and Morphine Abuse

ArticleYear
DRUG ADDICTION: A REVIEW.
    The Journal of school health, 1964, Volume: 34

    Topics: Adolescent; Amphetamine; Amphetamines; Barbiturates; Cannabis; Codeine; Heroin; Humans; Hydromorphon

1964
Environmental theory of drug addiction.
    General pharmacology, 1978, Volume: 9, Issue:5

    Topics: Amphetamine; Animals; Brain Chemistry; Enkephalins; Humans; Learning; Male; Memory; Mice; Morphine D

1978
Advances in the treatment of drug addiction.
    The Practitioner, 1972, Volume: 209, Issue:252

    Topics: Alcoholism; Amphetamine; Aversive Therapy; Barbiturates; Heroin; Humans; Lysergic Acid Diethylamide;

1972
Requirements and problems in urinalysis for abuse drugs: the role of gas chromatography.
    The American journal of medical technology, 1973, Volume: 39, Issue:6

    Topics: Amphetamine; Barbiturates; Chromatography, Gas; Chromatography, Thin Layer; Heroin Dependence; Human

1973
[Neurobiologic aspects of the morphine addictions].
    Die Naturwissenschaften, 1974, Volume: 61, Issue:6

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Catecholamines; Cocaine; Desipram

1974

Other Studies

58 other studies available for amphetamine and Morphine Abuse

ArticleYear
Qualitative differences between C57BL/6J and DBA/2J mice in morphine potentiation of brain stimulation reward and intravenous self-administration.
    Psychopharmacology, 2010, Volume: 208, Issue:2

    Topics: Amphetamine; Amphetamine-Related Disorders; Analgesics, Opioid; Animals; Behavior, Addictive; Behavi

2010
THE ADDICTION RESEARCH CENTER INVENTORY: STANDARDIZATION OF SCALES WHICH EVALUATE SUBJECTIVE EFFECTS OF MORPHINE, AMPHETAMINE, PENTOBARBITAL, ALCOHOL, LSD-25, PYRAHEXYL AND CHLORPROMAZINE.
    Psychopharmacologia, 1963, May-15, Volume: 4

    Topics: Alcohols; Amphetamine; Amphetamines; Antidepressive Agents; Behavior, Addictive; Benzopyrans; Chlorp

1963
THE ADDICTION RESEARCH CENTER INVENTORY: APPENDIX. I. ITEMS COMPRISING EMPIRICAL SCALES FOR SEVEN DRUGS. II. ITEMS WHICH DO NOT DIFFERENTIATE PLACEBO FROM ANY DRUG CONDITION.
    Psychopharmacologia, 1963, May-15, Volume: 4

    Topics: Alcohols; Amphetamine; Amphetamines; Antidepressive Agents; Appendix; Behavior, Addictive; Chlorprom

1963
DEVELOPMENT OF THE ADDICTION RESEARCH CENTER INVENTORY (ARCI): SELECTION OF ITEMS THAT ARE SENSITIVE TO THE EFFECTS OF VARIOUS DRUGS.
    Psychopharmacologia, 1963, May-15, Volume: 4

    Topics: Amphetamine; Amphetamines; Behavior, Addictive; Chlorpromazine; Humans; Lysergic Acid Diethylamide;

1963
DRUG ADDICTION. PHARMACOLOGICAL ASPECTS OF ADDICTION TO MORPHINE AND OTHER DRUGS.
    Proceedings of the Royal Society of Medicine, 1965, Volume: 58

    Topics: Amphetamine; Amphetamines; Aspirin; Behavior, Addictive; Drug Therapy; Hypnotics and Sedatives; Morp

1965
Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1

    Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal;

2004
Pharmacological studies of spinal cord adrenergic and cholinergic mechanisms and their relation to physical dependence on morphine.
    Psychopharmacologia, 1967, Aug-04, Volume: 11, Issue:3

    Topics: Amphetamine; Animals; Atropine; Dextroamphetamine; Dogs; Electric Stimulation; Humans; Methoxamine;

1967
Further studies on the acute dependence produced by morphine in opiate naive rats.
    Life sciences, 1982, Oct-11, Volume: 31, Issue:15

    Topics: Amphetamine; Animals; Corticosterone; Diazepam; Drug Tolerance; Humans; Male; Morphine; Morphine Dep

1982
Intraaccumbens injections of substance P, morphine and amphetamine: effects on conditioned place preference and behavioral activity.
    Brain research, 1998, Apr-20, Volume: 790, Issue:1-2

    Topics: Acute Disease; Amphetamine; Animals; Behavior, Animal; Conditioning, Psychological; Disease Models,

1998
Reciprocal changes in dopamine responsiveness in the nucleus accumbens shell and core and in the dorsal caudate-putamen in rats sensitized to morphine.
    Neuroscience, 1999, Volume: 90, Issue:2

    Topics: Amphetamine; Animals; Catalepsy; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; Grooming; Ma

1999
Stress or drug priming induces reinstatement of extinguished conditioned place preference.
    Neuroreport, 2000, Aug-21, Volume: 11, Issue:12

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Conditioning, Psychological; Electroshock;

2000
A single exposure to morphine induces long-lasting behavioural and neurochemical sensitization in rats.
    The European journal of neuroscience, 2001, Volume: 14, Issue:9

    Topics: Acetylcholine; Amphetamine; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Dose-Response Relat

2001
Precipitation of abstinence-like syndrome in morphine-dependent mice by pargyline.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:2

    Topics: Amantadine; Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism

1976
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
    The Journal of pediatrics, 1979, Volume: 94, Issue:6

    Topics: Amphetamine; Cocaine; Diazepam; Female; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant,

1979
Time course of the effects of naturally occurring cannabinoids on morphine abstinence syndrome.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:1

    Topics: Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Dronabinol; Humans; Levodo

1978
Conditioned avoidance behavior in pretrained rats intermittently treated with addictive drugs.
    Physiology & behavior, 1975, Volume: 15, Issue:3

    Topics: Amphetamine; Animals; Avoidance Learning; Body Weight; Conditioning, Operant; Dose-Response Relation

1975
Drug abuse in Denmark (Jutland and Funen). A forensic study based upon drugs seized in 1982-1987.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1988, Volume: 101, Issue:4

    Topics: Amphetamine; Cocaine; Cross-Sectional Studies; Denmark; Heroin Dependence; Humans; Illicit Drugs; Ma

1988
Effects of chronic treatment with diazepam, phenobarbital, or amphetamine on naloxone-precipitated morphine withdrawal.
    Drug and alcohol dependence, 1985, Volume: 15, Issue:4

    Topics: Amphetamine; Animals; Corticosterone; Diazepam; Male; Mice; Morphine Dependence; Motor Activity; Nal

1985
[Biochemical, pharmacological and clinical studies with opiates, cannabinoles, stimulants and hallucinogens].
    Das Offentliche Gesundheitswesen, 1971, Volume: 33, Issue:9

    Topics: Amphetamine; Animals; Cannabis; Drug Tolerance; Hallucinogens; Haplorhini; Humans; Lysergic Acid Die

1971
[Effects of drug misuse in traffic].
    Das Offentliche Gesundheitswesen, 1971, Volume: 33, Issue:9

    Topics: Accidents, Traffic; Amphetamine; Automobile Driving; Cannabis; Hallucinogens; Humans; Lysergic Acid

1971
Personality attributes of the young, nonaddicted drug abuser.
    The International journal of the addictions, 1972, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Antisocial Personality Disorder; Anxiety; Barbiturates;

1972
[Significance of catecholamines for the manifestation of morphine withdrawal in the rat].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:7

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Desipramine; D

1974
[Multidimensional classification of drug consumption in young people].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1972, Volume: 216, Issue:3

    Topics: Adult; Amphetamine; Analysis of Variance; Antitussive Agents; Cannabis; Formularies as Topic; Halluc

1972
Adolescents--drug abuse and addiction.
    British medical journal, 1972, Dec-02, Volume: 4, Issue:5839

    Topics: Adolescent; Adult; Affective Symptoms; Amphetamine; Family Practice; Heroin; Humans; Lysergic Acid D

1972
Role of brain noradrenaline in morphine-induced stereotyped behaviour.
    Psychopharmacologia, 1972, Volume: 27, Issue:3

    Topics: Acetamides; Amphetamine; Animals; Antihypertensive Agents; Behavior, Animal; Brain; Butyrophenones;

1972
[Aspects of the narcotic problem].
    Der Anaesthesist, 1973, Volume: 22, Issue:1

    Topics: Adolescent; Amphetamine; Barbiturates; Cannabis; Child; Crime; Drug and Narcotic Control; Germany, W

1973
The drug scene: acute drug syndromes.
    Postgraduate medicine, 1973, Volume: 53, Issue:4

    Topics: Alcoholic Intoxication; Amphetamine; Atropa belladonna; Atropine; Barbiturates; Cannabis; Diagnosis,

1973
[Gynecological-obstetrical problems in female drug users and drug addicts].
    Geburtshilfe und Frauenheilkunde, 1973, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Amenorrhea; Amphetamine; Barbiturates; Dronabinol; Dysmenorrhea; Female; Hallucin

1973
Relapse to morphine use in dog.
    Psychopharmacologia, 1973, Volume: 30, Issue:1

    Topics: Amphetamine; Animals; Disease Models, Animal; Dogs; Humans; Morphine; Morphine Dependence; Recurrenc

1973
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
    Psychopharmacologia, 1973, Volume: 32, Issue:2

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Me

1973
[Three year drug scene in a middle-sized city on the edge of the Ruhr area. Report of experiences from the viewpoint of a clinical physician].
    Die Medizinische Welt, 1973, Jan-26, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Amphetamine; Cannabis; Female; Germany, West; Humans; Lysergic Acid Diethylamide;

1973
Multiple-drug addiction in New York City in a selected population group.
    Public health reports (Washington, D.C. : 1896), 1966, Volume: 81, Issue:8

    Topics: Amphetamine; Barbiturates; Female; Heroin; Humans; Male; Morphine Dependence; New York City; Opium;

1966
The adolescent addict. The progression of youth through the drug culture.
    Clinical pediatrics, 1972, Volume: 11, Issue:7

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Barbiturates; Cannabis; Child; Cocaine; Hallucinogens;

1972
The changing face of heroin addiction in the Haight-Ashbury.
    The International journal of the addictions, 1972, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Amphetamine; California; Cannabis; Child; Community Health Services; Female; Hero

1972
Heroin addicts' views of commonly abused drugs: a semantic differential approach.
    Journal of personality assessment, 1972, Volume: 36, Issue:4

    Topics: Adult; Amphetamine; Cannabis; Female; Heroin; Humans; Lysergic Acid Diethylamide; Male; Methadone; M

1972
Soft drugs, the campus, and you.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1972, Volume: 14, Issue:9

    Topics: Amphetamine; Attitude; Cannabis; Ethanol; Heroin; Humans; Lysergic Acid Diethylamide; Models, Theore

1972
Age of onset of drug abuse in psychiatric inpatients.
    Archives of general psychiatry, 1972, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Antisocial Personality Disorder; Barbiturates; Cannabis

1972
Drug use in Vietnam. A survey among army personnel in the two northern corps.
    Archives of general psychiatry, 1972, Volume: 26, Issue:3

    Topics: Adult; Age Factors; Amphetamine; Attitude; Barbiturates; Cannabis; Educational Status; Family Charac

1972
Aggressive behaviour induced by marihuana compounds and amphetamine in rats previously made dependent on morphine.
    Experientia, 1972, May-15, Volume: 28, Issue:5

    Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Cannabis; Food Deprivation; Humans; Morphine Dep

1972
Evaluation of drug abuse.
    American family physician, 1972, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Alcohol Drinking; Amphetamine; Barbiturates; Behavior; Cannabis; Child; Cocaine;

1972
Development of morphine dependence in rats: lack of effect of previous ingestion of other drugs.
    Psychopharmacologia, 1971, Volume: 20, Issue:4

    Topics: Amobarbital; Amphetamine; Animals; Chlordiazepoxide; Cocaine; Drinking Behavior; Drug Antagonism; Et

1971
The changing pattern of narcotic addiction in Britain--1959 to 1969.
    The International journal of the addictions, 1971, Volume: 6, Issue:1

    Topics: Adult; Age Factors; Amphetamine; Barbiturates; Cannabis; Cocaine; Drug and Narcotic Control; Heroin;

1971
The dimensions of drug dependence in the United Kingdom.
    The International journal of the addictions, 1971, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Barbiturates; Cannabis; Crime; Female; Geography; Heroi

1971
Drug culture in the seventies.
    American journal of public health, 1971, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Amphetamine; Cannabis; Costs and Cost Analysis; Drug and Narcotic Control; Heroin

1971
Morphine-withdrawal aggression: sensitization by amphetamines.
    Psychopharmacologia, 1971, Volume: 22, Issue:3

    Topics: Aggression; Amphetamine; Animals; Dextroamphetamine; Humans; Hydroxylamines; Male; Methylphenidate;

1971
A case-note study of 134 out-patient drug addicts over a 17-month period.
    The British journal of addiction to alcohol and other drugs, 1971, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Cocaine; Drug and Narcotic Control; Female; Heroin; Hum

1971
Man and drugs.
    Archives of environmental health, 1970, Volume: 20, Issue:1

    Topics: Amphetamine; Barbiturates; Cannabis; Central Nervous System; Heroin; Humans; Legislation, Drug; Lyse

1970
Drug dependence: pharmacological and physiological aspects.
    Journal of the Royal College of Physicians of London, 1970, Volume: 4, Issue:3

    Topics: Amphetamine; Animals; Barbiturates; Brain; Cannabis; Central Nervous System; Cocaine; Drug Tolerance

1970
The New Haven Methadone Maintenance Program.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Amphetamine; Barbiturates; Cocaine; Community Health Services; Community Mental Health Servic

1970
Methadone related deaths in New York City.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Alcoholism; Amphetamine; Barbiturates; Child, Preschool; Community Health Services; Evaluatio

1970
Secondary drug use among heroin users.
    The International journal of the addictions, 1970, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Aged; Amphetamine; Barbiturates; Cannabis; Cocaine; Crime; Educational Status; Et

1970
Metastatic endophthalmitis associated with injection of addictive drugs.
    American journal of ophthalmology, 1971, Volume: 71, Issue:5

    Topics: Adult; Amphetamine; Aspergillosis; Cannabis; Eye Diseases; Heroin; Humans; Inflammation; Injections,

1971
An epidemiology of drug use-abuse.
    American journal of public health, 1971, Volume: 61, Issue:9

    Topics: Amphetamine; Cannabis; Demography; Drug and Narcotic Control; Epidemiologic Methods; Humans; Japan;

1971
Drug taking in adolescent girls: factors associated with the progression to narcotic use.
    British medical journal, 1971, Jun-12, Volume: 2, Issue:5762

    Topics: Adolescent; Amphetamine; Cannabis; Cocaine; Educational Status; Family; Female; Heroin; Humans; Juve

1971
Recent changes in the incidence in all types of drug dependence in Great Britain.
    Proceedings of the Royal Society of Medicine, 1968, Volume: 61, Issue:2

    Topics: Adult; Alcoholism; Amphetamine; Barbiturates; Cannabis; Cocaine; Female; Hallucinogens; Heroin; Huma

1968
Characteristics of drug abusers admitted to a psychiatric hospital.
    JAMA, 1968, Jul-15, Volume: 205, Issue:3

    Topics: Adult; Age Factors; Amphetamine; Antisocial Personality Disorder; Antitussive Agents; Barbiturates;

1968
[Addiction treatment center at Ulleråker hospital 3. Follow-up supervision of amphetamine addicts].
    Lakartidningen, 1969, Mar-26, Volume: 66, Issue:13

    Topics: Amphetamine; Female; Follow-Up Studies; Humans; Male; Morphine Dependence; Substance-Related Disorde

1969
Patterns and profiles of addiction and drug abuse.
    Archives of general psychiatry, 1966, Volume: 15, Issue:5

    Topics: Amphetamine; Drug-Related Side Effects and Adverse Reactions; Ethnology; Hallucinogens; Humans; Juri

1966