Page last updated: 2024-10-25

amphetamine and Mood Disorders

amphetamine has been researched along with Mood Disorders in 8 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.

Research Excerpts

ExcerptRelevanceReference
"A potentiating mechanism in drug use disorders appears to be synaptic plasticity, which is regulated by dopamine transmission."1.37Effects of dopamine and glutamate on synaptic plasticity: a computational modeling approach for drug abuse as comorbidity in mood disorders. ( Kikuchi, S; Qi, Z; Tretter, F; Voit, EO, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Der-Avakian, A1
D'Souza, MS1
Pizzagalli, DA1
Markou, A1
Furlotti, G1
Alisi, MA1
Cazzolla, N1
Dragone, P1
Durando, L1
Magarò, G1
Mancini, F1
Mangano, G1
Ombrato, R1
Vitiello, M1
Armirotti, A1
Capurro, V1
Lanfranco, M1
Ottonello, G1
Summa, M1
Reggiani, A1
Pan, JQ1
Lewis, MC1
Ketterman, JK1
Clore, EL1
Riley, M1
Richards, KR1
Berry-Scott, E1
Liu, X1
Wagner, FF1
Holson, EB1
Neve, RL1
Biechele, TL1
Moon, RT1
Scolnick, EM1
Petryshen, TL1
Haggarty, SJ1
Marcus, SC1
Durkin, M1
Qi, Z1
Kikuchi, S1
Tretter, F1
Voit, EO1
Latapy, C1
Rioux, V1
Guitton, MJ1
Beaulieu, JM1
Weiss, JM1
West, CH1
Emery, MS1
Bonsall, RW1
Moore, JP1
Boss-Williams, KA1
Siever, L1
Insel, T1
Uhde, T1

Reviews

2 reviews available for amphetamine and Mood Disorders

ArticleYear
Rats selectively-bred for behavior related to affective disorders: proclivity for intake of alcohol and drugs of abuse, and measures of brain monoamines.
    Biochemical pharmacology, 2008, Jan-01, Volume: 75, Issue:1

    Topics: Alcohol Drinking; Amphetamine; Animals; Biogenic Monoamines; Brain; Brain Chemistry; Breeding; Cocai

2008
Noradrenergic challenges in the affective disorders.
    Journal of clinical psychopharmacology, 1981, Volume: 1, Issue:4

    Topics: Amphetamine; Behavior; Clonidine; Growth Hormone; Humans; Hydrocortisone; Mood Disorders; Neurons; N

1981

Other Studies

6 other studies available for amphetamine and Mood Disorders

ArticleYear
Assessment of reward responsiveness in the response bias probabilistic reward task in rats: implications for cross-species translational research.
    Translational psychiatry, 2013, Aug-27, Volume: 3

    Topics: Amphetamine; Animals; Benzothiazoles; Conditioning, Operant; Discrimination Learning; Disease Models

2013
Hit Optimization of 5-Substituted-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamides: Potent Glycogen Synthase Kinase-3 (GSK-3) Inhibitors with in Vivo Activity in Model of Mood Disorders.
    Journal of medicinal chemistry, 2015, Nov-25, Volume: 58, Issue:22

    Topics: Adenosine Triphosphate; Amphetamine; Animals; Binding, Competitive; Central Nervous System Stimulant

2015
AKT kinase activity is required for lithium to modulate mood-related behaviors in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:7

    Topics: Amphetamine; Analysis of Variance; Animals; Antimanic Agents; Cell Line, Transformed; Corpus Striatu

2011
Stimulant adherence and academic performance in urban youth with attention-deficit/hyperactivity disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2011, Volume: 50, Issue:5

    Topics: Achievement; Adolescent; Amphetamine; Anxiety Disorders; Attention Deficit and Disruptive Behavior D

2011
Effects of dopamine and glutamate on synaptic plasticity: a computational modeling approach for drug abuse as comorbidity in mood disorders.
    Pharmacopsychiatry, 2011, Volume: 44 Suppl 1

    Topics: Amphetamine; Comorbidity; Computer Simulation; Dopamine; Dopamine Uptake Inhibitors; GABAergic Neuro

2011
Selective deletion of forebrain glycogen synthase kinase 3β reveals a central role in serotonin-sensitive anxiety and social behaviour.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2012, Sep-05, Volume: 367, Issue:1601

    Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anxiety; Enzyme Activation; Female; Gene Deletion; Gene S

2012