amphetamine has been researched along with Inadequate Sleep in 34 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Amphetamine and L-dopa pretreatment attenuated the increases in apomorphine-induced stereotypy and aggression in REMSD rats, but ECS selectively reduced apomorphine-induced aggression." | 7.67 | Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments. ( Braz, S; Ferreira, TM; Silveira Filho, NG; Troncone, LR; Tufik, S, 1988) |
| " The antidepressant imipramine, which shows pro-manic properties in patients with bipolar disorder (BPD), also enhanced phospho-MARCKS in prefrontal cortex in vivo." | 3.75 | Glutamate receptors as targets of protein kinase C in the pathophysiology and treatment of animal models of mania. ( Cirelli, C; Du, J; Falke, C; Machado-Vieira, R; Manji, HK; Szabo, ST; Tononi, G; Wang, Y; Wei, Y; Yuan, P, 2009) |
| " Amphetamine and L-dopa pretreatment attenuated the increases in apomorphine-induced stereotypy and aggression in REMSD rats, but ECS selectively reduced apomorphine-induced aggression." | 3.67 | Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments. ( Braz, S; Ferreira, TM; Silveira Filho, NG; Troncone, LR; Tufik, S, 1988) |
| "After 48 hr." | 2.67 | Parsing attentional components during a simple reaction time task using sleep deprivation and amphetamine intervention. ( Cochran, JC; Newhouse, PA; Penetar, DM; Thorne, DR, 1992) |
| "d-Amphetamine was more powerful than l-amphetamine in reversing sleep deprivation effects on vigilance and on waking EEG." | 2.64 | Sleep deprivation deficits and their reversal by d- and l-amphetamine. ( Branconnier, R; Hartmann, E; Orzack, MH, 1977) |
| "To explore the relationship between sleep deprivation and amphetamine-induced psychosis." | 1.72 | Sleep Deprivation & Amphetamine Induced Psychosis. ( Alshehri, MH; Bahanan, AO; Elag, KA; Shalaby, AS, 2022) |
| "Dextro-amphetamine and sleep deprivation induced hyperactivity and increased histone deacetylase and DNA methyltransferase activities in the animal's brain." | 1.62 | Role of epigenetic regulatory enzymes in animal models of mania induced by amphetamine and paradoxical sleep deprivation. ( Andersen, ML; Dal-Pont, GC; Gava, FF; Nadas, GB; Quevedo, J; Resende, WR; Tye, SJ; Valvassori, SS; Varela, RB, 2021) |
| "Prolonged sleep deprivation in rats produces a characteristic syndrome of increase in food intake accompanied by, paradoxically, decrease in weight, suggesting a potential alteration in motivation for food reward." | 1.36 | REM sleep deprivation produces a motivational deficit for food reward that is reversed by intra-accumbens amphetamine in rats. ( Baldo, BA; Benca, RM; Hanlon, EC; Kelley, AE, 2010) |
| "Prior rodent studies have used sleep deprivation to examine this relationship." | 1.35 | Sleep deprivation and Pavlovian fear conditioning. ( Anagnostaras, SG; Cai, DJ; Harrison, EM; Sage, JR; Shuman, T, 2009) |
| "The effects of paradoxical sleep deprivation (that worsens psychotic symptoms) and the performance in a latent inhibition protocol (an animal model of schizophrenia) were also verified." | 1.35 | Neuroleptic drugs revert the contextual fear conditioning deficit presented by spontaneously hypertensive rats: a potential animal model of emotional context processing in schizophrenia? ( Abílio, VC; Andersen, ML; Calzavara, MB; Frussa-Filho, R; Kameda, SR; Levin, R; Medrano, WA; Silva, RH; Tufik, S, 2009) |
| "Environmental enrichment or paradoxical sleep deprivation (PSD) has been shown to modify some responses elicited by drugs of abuse." | 1.34 | Effects of environmental enrichment and paradoxical sleep deprivation on open-field behavior of amphetamine-treated mice. ( Abílio, VC; Andersen, ML; Calzavara, MB; Frussa-Filho, R; Fukushiro, DF; Lopez, GB; Trombin, TF; Tufik, S, 2007) |
| "The effects of paradoxical sleep deprivation (PSD-48 h) on the conditioned and unconditioned components of behavioural sensitization to amphetamine (two injections of 2." | 1.32 | Paradoxical sleep deprivation potentiates amphetamine-induced behavioural sensitization by increasing its conditioned component. ( Andersen, ML; Chinen, CC; de Araujo, NP; Frussa-Filho, R; Gonçalves, MT; Tufik, S, 2004) |
| "Although sleep deprivation often occurs during stressful or threatening situations, the effects of sleep loss on defensive and coping behaviors are not well known." | 1.32 | REM sleep deprivation induces changes in coping responses that are not reversed by amphetamine. ( Benca, RM; Fahy, JL; Kalin, NH; Martinez-Gonzalez, D; Obermeyer, W; Riboh, M, 2004) |
| "Modafinil is a newly discovered waking substance now being used in the treatment of hypersomnia and narcolepsy." | 1.31 | Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat. ( Frydman, A; Gervasoni, D; Hou, Y; Jouvet, M; Lin, JS; Rambert, F; Vanni-Mercier, G, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (50.00) | 18.7374 |
| 1990's | 2 (5.88) | 18.2507 |
| 2000's | 11 (32.35) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 2 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Shalaby, AS | 1 |
| Bahanan, AO | 1 |
| Alshehri, MH | 1 |
| Elag, KA | 1 |
| Varela, RB | 1 |
| Resende, WR | 1 |
| Dal-Pont, GC | 1 |
| Gava, FF | 1 |
| Nadas, GB | 1 |
| Tye, SJ | 1 |
| Andersen, ML | 4 |
| Quevedo, J | 1 |
| Valvassori, SS | 1 |
| Kameda, SR | 2 |
| Fukushiro, DF | 2 |
| Trombin, TF | 2 |
| Sanday, L | 1 |
| Wuo-Silva, R | 1 |
| Saito, LP | 1 |
| Tufik, S | 5 |
| D'Almeida, V | 1 |
| Frussa-Filho, R | 4 |
| Ramsey, CS | 1 |
| Werchan, PM | 1 |
| Isdahl, WM | 1 |
| Fischer, J | 1 |
| Gibbons, JA | 1 |
| Szabo, ST | 1 |
| Machado-Vieira, R | 1 |
| Yuan, P | 1 |
| Wang, Y | 1 |
| Wei, Y | 1 |
| Falke, C | 1 |
| Cirelli, C | 1 |
| Tononi, G | 1 |
| Manji, HK | 1 |
| Du, J | 1 |
| Cai, DJ | 1 |
| Shuman, T | 1 |
| Harrison, EM | 1 |
| Sage, JR | 1 |
| Anagnostaras, SG | 1 |
| Hanlon, EC | 1 |
| Benca, RM | 2 |
| Baldo, BA | 1 |
| Kelley, AE | 1 |
| LATIES, VG | 1 |
| Ponomarenko, AA | 1 |
| Lin, JS | 3 |
| Selbach, O | 1 |
| Haas, HL | 1 |
| Gonçalves, MT | 1 |
| de Araujo, NP | 1 |
| Chinen, CC | 1 |
| Martinez-Gonzalez, D | 1 |
| Obermeyer, W | 1 |
| Fahy, JL | 1 |
| Riboh, M | 1 |
| Kalin, NH | 1 |
| Calzavara, MB | 2 |
| Lopez, GB | 1 |
| Abílio, VC | 2 |
| Soya, A | 1 |
| Song, YH | 1 |
| Kodama, T | 1 |
| Honda, Y | 1 |
| Fujiki, N | 1 |
| Nishino, S | 1 |
| Medrano, WA | 1 |
| Levin, R | 1 |
| Silva, RH | 1 |
| Jouvet, M | 2 |
| Gervasoni, D | 1 |
| Hou, Y | 1 |
| Vanni-Mercier, G | 1 |
| Rambert, F | 1 |
| Frydman, A | 1 |
| Hou, YP | 1 |
| Niculescu, AB | 1 |
| Kelsoe, JR | 1 |
| Sachar, EJ | 1 |
| Carlini, EA | 1 |
| Hartmann, E | 2 |
| Orzack, MH | 1 |
| Branconnier, R | 1 |
| Cochran, JC | 1 |
| Thorne, DR | 1 |
| Penetar, DM | 1 |
| Newhouse, PA | 1 |
| Troncone, LR | 1 |
| Ferreira, TM | 1 |
| Braz, S | 1 |
| Silveira Filho, NG | 1 |
| Ferguson, J | 1 |
| Dement, W | 1 |
| Voronka, GSh | 1 |
| Demin, NN | 1 |
| Rubinskaia, NL | 1 |
| Stern, WC | 2 |
| Morgane, PJ | 1 |
| Eichelman, B | 1 |
| Meyer, RE | 1 |
| DiMascio, A | 1 |
| Stifler, L | 1 |
| Pearlman, CA | 1 |
| Greenberg, R | 1 |
| Sanders, AF | 1 |
| Bunt, AA | 1 |
| Hartmann, EL | 1 |
| Krsiak, M | 1 |
| Jankú, I | 1 |
7 reviews available for amphetamine and Inadequate Sleep
| Article | Year |
|---|---|
Convergent functional genomics: application to bipolar disorder.
Topics: Amphetamine; Animals; Bipolar Disorder; Cloning, Molecular; Gene Expression Profiling; Genetic Linka | 2001 |
Evidence for neuroendocrine abnormalities in the major mental illnesses.
Topics: Adrenocorticotropic Hormone; Aged; Amphetamine; Bipolar Disorder; Chlorpromazine; Circadian Rhythm; | 1975 |
The D-state and norepinephrine-dependent systems.
Topics: Adult; Amphetamine; Animals; Attention; Brain; Brain Chemistry; Cats; Child; Depression; Feedback; H | 1970 |
Theoretical view of REM sleep function: maintenance of catecholamine systems in the central nervous system.
Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Brain Chemistry; Catecholamines; Cats; Electroen | 1974 |
The catecholamines and aggressive behavior.
Topics: Aggression; Amphetamine; Anger; Animals; Behavior, Animal; Brain Stem; Catecholamines; Dihydroxyphen | 1973 |
Medical-psychological implications of recent sleep research.
Topics: Adaptation, Psychological; Amphetamine; Barbiturates; Central Nervous System Stimulants; Chloral Hyd | 1970 |
Some remarks on the effects of drugs, lack of sleep and loud noise on human performance.
Topics: Amphetamine; Cognition; Decision Making; Ethanol; Hypnotics and Sedatives; Memory, Short-Term; Noise | 1971 |
2 trials available for amphetamine and Inadequate Sleep
| Article | Year |
|---|---|
Sleep deprivation deficits and their reversal by d- and l-amphetamine.
Topics: Adult; Amphetamine; Attention; Dextroamphetamine; Electroencephalography; Emotions; Humans; Male; Sl | 1977 |
Parsing attentional components during a simple reaction time task using sleep deprivation and amphetamine intervention.
Topics: Adult; Amphetamine; Arousal; Attention; Humans; Male; Placebos; Reaction Time; Sleep Deprivation; Ta | 1992 |
25 other studies available for amphetamine and Inadequate Sleep
| Article | Year |
|---|---|
Sleep Deprivation & Amphetamine Induced Psychosis.
Topics: Amphetamine; Amphetamine-Related Disorders; Humans; Psychoses, Substance-Induced; Psychotic Disorder | 2022 |
Role of epigenetic regulatory enzymes in animal models of mania induced by amphetamine and paradoxical sleep deprivation.
Topics: Amphetamine; Animals; Antimanic Agents; Disease Models, Animal; Epigenesis, Genetic; Male; Mania; Mi | 2021 |
The effects of paradoxical sleep deprivation on amphetamine-induced behavioral sensitization in adult and adolescent mice.
Topics: Age Factors; Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Central Nervous | 2014 |
Acceleration tolerance at night with acute fatigue and stimulants.
Topics: Acceleration; Adaptation, Physiological; Adult; Aerospace Medicine; Amphetamine; Analysis of Varianc | 2008 |
Glutamate receptors as targets of protein kinase C in the pathophysiology and treatment of animal models of mania.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Bipolar Disorder; Cell Membrane; Central Ner | 2009 |
Sleep deprivation and Pavlovian fear conditioning.
Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Conditioning, Classical; Fear; Femal | 2009 |
REM sleep deprivation produces a motivational deficit for food reward that is reversed by intra-accumbens amphetamine in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Do | 2010 |
Modification of affect, social behaviour and performance by sleep deprivation and drugs.
Topics: Amphetamine; Amphetamines; Barbiturates; Behavior; Emotions; Humans; Sleep; Sleep Deprivation; Socia | 1961 |
Temporal pattern of hippocampal high-frequency oscillations during sleep after stimulant-evoked waking.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Dose-Response Relatio | 2003 |
Paradoxical sleep deprivation potentiates amphetamine-induced behavioural sensitization by increasing its conditioned component.
Topics: Amphetamine; Animals; Conditioning, Psychological; Male; Mice; Mice, Inbred C57BL; Motor Activity; S | 2004 |
REM sleep deprivation induces changes in coping responses that are not reversed by amphetamine.
Topics: Adaptation, Psychological; Amphetamine; Animals; Dopamine Agents; Grooming; Locomotion; Male; Maze L | 2004 |
Effects of environmental enrichment and paradoxical sleep deprivation on open-field behavior of amphetamine-treated mice.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Environment; Euphoria | 2007 |
CSF histamine levels in rats reflect the central histamine neurotransmission.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Circadian Rhyt | 2008 |
Neuroleptic drugs revert the contextual fear conditioning deficit presented by spontaneously hypertensive rats: a potential animal model of emotional context processing in schizophrenia?
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Conditioning, Psychological; Disease M | 2009 |
[Recent data on experimental insomnia in the cat].
Topics: Amphetamine; Animals; Catecholamines; Cats; Humans; Medulla Oblongata; Nialamide; Reticular Formatio | 1966 |
Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Cats; Central Nervous System Stimulants; Disorders of Ex | 2000 |
Effects of modafinil and amphetamine on sleep-wake cycle after sleep deprivation in cats.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Cats; Central Nervous System Stimulants; Electroencephal | 1999 |
Further studies of the aggressive behavior induced by delta9-tetrahydrocannabinol in REM sleep-deprived rats.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Dronabinol; Grooming; Humans; Lysergic Acid Diethylam | 1977 |
Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Bromocriptine; Carbidopa; Dopamine; Imipramine; Levod | 1988 |
The behavioral effects of amphetamine on REM deprived rats.
Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Female; Humans; Male; Rats; Sexual Behavior, Ani | 1969 |
[RNA content in neurons and their cell satellites in the supraoptic nucleus of the rat brain in natural sleep, its REM phase deprivation, and amphetamine insomnia].
Topics: Amphetamine; Animals; Hypothalamus; Neuroglia; Neurons; Rats; RNA; Sleep; Sleep Deprivation; Sleep, | 1972 |
[RNA in neurons and their glial cell-satellites in the rat red nucleus during natural sleep, deprivation of its paradoxical phase and phenamine insomnia].
Topics: Amphetamine; Animals; Humans; Male; Neuroglia; Rats; Red Nucleus; RNA; Sleep; Sleep Deprivation; Sle | 1973 |
Personality differences in the response to stimulant drugs administered during a sleep-deprived state.
Topics: Adult; Affect; Amphetamine; Blood Pressure; Ethylamines; Fatigue; Humans; Male; Mental Fatigue; Moto | 1970 |
Reduced amphetamine lethality following chronic stress.
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Amphetamine; Animals; Atrophy; Hypertrophy; Immersion; | 1972 |
The dependence of the effect of some psychotropic drugs on the activation of the central nervous system.
Topics: Amphetamine; Animals; Barbiturates; Central Nervous System; Chlorpromazine; Injections, Intraperiton | 1967 |